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Material Safety Data Sheet: L-Lysine-L-Aspartate

Identification

Product Name: L-Lysine-L-Aspartate
Chemical Formula: C10H20N2O6
CAS Number: 27348-32-9
Manufacturer: Common producers include biotechnology and pharmaceutical companies distributed worldwide
Synonyms: Bis(L-lysinium) L-aspartate, Lys-Asp complex
Intended Use: Amino acid supplement, used in food and pharmaceutical preparations
Contact Details for Inquiry: Reach out to safety representative through supplier or manufacturer
Emergency Telephone Number: Reference emergency line on shipping documents or on product label

Hazard Identification

Hazard Classification: Not classified as hazardous under GHS criteria for most jurisdictions
Physical Hazards: Fine powder may present dust hazards with improper handling, may cause respiratory irritation
Health Hazards: May cause mild eye or skin irritation in sensitive individuals, ingestion in large quantities may lead to gastrointestinal discomfort
Environmental Hazards: No significant aquatic or soil toxicity reported, not classified as hazardous to the environment
Signal Words: None
Pictograms: None required under standard GHS
Precautionary Statements: Avoid breathing dust, wash hands after handling, avoid eye contact, wear protective clothing when handling bulk amounts
Other Risks: Dust accumulation near ignition sources could present explosion risk in rare cases

Composition / Information on Ingredients

Chemical Name: L-Lysine-L-Aspartate
Concentration: 98–100% pure
Impurities: Possible trace-level residues of parent amino acids or manufacturing byproducts, none known with acute toxicological relevance
Additives: No excipients or stabilizers in standard technical or pharmaceutical grade
Relevant Identifiers: Amino acid derivative with unique dual structure utilizing both lysine and aspartic acid residues

First Aid Measures

Inhalation: Move individual to fresh air, support breathing if irritation occurs, seek medical attention if symptoms persist or allergic reaction develops
Skin Contact: Wash area with soap and water, remove contaminated clothing, seek medical guidance if irritation erupts
Eye Contact: Rinse carefully with water or saline for several minutes, remove contact lenses, seek attention if redness or discomfort continues
Ingestion: Rinse mouth with water, drink water to dilute, do not induce vomiting, seek medical advice for significant ingestion or any unusual symptoms
Specific Advice for Healthcare Providers: Supportive care based on symptomatology, no specific antidote required

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, CO2, or foam for extinguishing fires involving organic powder
Unsuitable Extinguishing Media: Avoid high-volume water jet that may spread dust
Special Hazards: Dust may form explosive mixtures with air in extreme conditions, combustion yields carbon oxides and nitrogen oxides
Protective Equipment for Firefighters: Wear full protective gear including mask with positive-pressure self-contained breathing apparatus
Additional Precautions: Prevent runoff from entering drains, isolate area, cool containers exposed to flames with water spray

Accidental Release Measures

Personal Precautions: Wear respiratory protection for dust, use gloves and goggles, avoid contact with eyes and skin
Environmental Precautions: Prevent material from entering watercourses, sewers, or soil, collect for proper disposal
Cleanup Methods: Contain spill with inert absorbent, sweep or vacuum up without generating dust, dispose of in compliance with local regulations
Emergency Procedures: Evacuate unnecessary personnel, ventilate area, report large spills to safety manager or local authorities if appropriate

Handling and Storage

Safe Handling: Work in a well-ventilated space, avoid dust generation, use personal protection for bulk handling, wash after handling
Storage Requirements: Store in tightly sealed container in a cool, dry place, away from direct sunlight and heat sources, segregate from incompatible substances such as strong oxidizers
Incompatibilities: Avoid mixing with strong acids, bases, or oxidizing agents
Storage Temperature: Preferred range between 15–25°C (59–77°F) for optimal shelf life
Additional Practices: Label containers clearly, monitor for clumping or discoloration which may signal deterioration

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for this substance under OSHA, NIOSH, or ACGIH
Engineering Controls: General dilution ventilation, use of local exhaust for dust-producing operations, no open handling in confined spaces
Respiratory Protection: Use NIOSH-approved dust mask for bulk handling
Eye Protection: Safety goggles
Skin Protection: Gloves made of nitrile or latex, use lab coats or coveralls for full body protection
Other Protective Equipment: Eye wash stations and safety showers in work area recommended
Hygiene Measures: No eating, drinking, or smoking during handling, wash hands thoroughly after exposure

Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Mild, characteristic amino acid scent
pH (aqueous solution): 5.5–7.0 at 10% solution
Melting Point: Decomposes above 200°C without defined melting
Solubility: Soluble in water
Boiling Point: Not applicable for solid
Vapor Pressure: Not volatile
Relative Density: Around 1.5 g/cm³
Partition Coefficient (log Kow): Not determined for most preparations
Other Properties: Non-flammable in typical use, non-explosive unless significant dust buildup in air

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Non-reactive under normal conditions of use and storage
Hazardous Reactions: No known dangerous reactions in standard applications
Conditions to Avoid: Excessive humidity, heat, strong oxidizers, and open flames
Incompatible Materials: Powerful oxidizing or reducing agents, strong acids, and bases
Decomposition Products: Decomposition may yield carbon dioxide, carbon monoxide, nitrogen oxides at high temperature

Toxicological Information

Acute Toxicity: No significant toxicity expected at occupational or dietary levels
Chronic Toxicity: No evidence of chronic toxicity in repeated-dose studies with similar amino acid derivatives
Routes of Exposure: Inhalation, ingestion, dermal contact
Potential Health Effects: May cause slight mouth, throat, or stomach discomfort if large amounts swallowed; dust may irritate airways; rare cases of contact dermatitis reported with prolonged exposure
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a carcinogen
Other Data: No mutagenic or reproductive risks found in routine laboratory research
Symptomatology: Mild and transient, generally resolves without intervention

Ecological Information

Eco-Toxicity: No significant toxicity to aquatic life at levels expected from accidental release
Persistence/Degradability: Readily biodegradable through standard soil and water microbial processes
Bioaccumulative Potential: Low, not expected to persist in food chains
Mobility in Soil: High, due to water solubility
Other Adverse Effects: None identified with standard use or unintentional environmental release

Disposal Considerations

Waste Treatment Methods: Dispose according to local, regional, or national regulations
Waste Classification: Considered non-hazardous waste pending relevant jurisdiction
Disposal of Containers: Clean, triple-rinse, and recycle or dispose as non-hazardous containers
Avoid Release: Do not allow large quantities to enter soil, waterways, or drains
Special Instructions: Seek guidance from waste contractor for unusual disposal circumstances or large quantities

Transport Information

UN Number: Not assigned, not regulated as dangerous goods
Transport Hazard Class: Not classified for road (ADR), sea (IMDG), or air (IATA) transit
Packing Group: None required
Proper Shipping Name: L-Lysine-L-Aspartate
Transport Labels: No label required
Special Precautions: Secure outer packaging to prevent breakage or spillage, protect from moisture during transit
Additional Notes: Transport according to good industrial hygiene and organizational best practices

Regulatory Information

Safety and Health Regulations: Not specifically regulated under US OSHA Hazard Communication Standard
Chemical Safety Assessment: Review available as part of REACH dossiers in the EU
TSCA Inventory: Substance listed
DSL/NDSL: Present in relevant substances lists within Canada
REACH Status: Registered for use in Europe, check with supplier for the most current authorization
Other Standards: Not subject to California Proposition 65, not regulated under other chemical security acts
Labelling Needs: Follow workplace regulations for labelling non-hazardous chemicals