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Material Safety Data Sheet (MSDS) for L-Lysine Dihydrochloride

Identification

Product Name: L-Lysine Dihydrochloride
Synonyms: L-2,6-Diaminohexanoic acid dihydrochloride, Lysine hydrochloride
Chemical Formula: C6H14N2O2·2HCl
CAS Number: 657-27-2
Recommended Use: Nutritional additive, laboratory chemical, food additive, feed supplement
Supplier Contact: Manufacturer’s details provided on container label
Emergency Contact Number: Provided by manufacturer or local poison control facility

Hazard Identification

GHS Classification: Not classified as hazardous according to GHS
Physical Hazards: None identified for routine handling
Health Hazards: May cause mild irritation if inhaled or on contact with skin or eyes; ingestion in large quantities may result in gastrointestinal discomfort
Environmental Hazards: Not considered a hazard to aquatic life or the environment in standard quantities
Pictograms: None required
Signal Word: None
Hazard statements: No significant hazards reported

Composition / Information on Ingredients

Chemical Name: L-Lysine Dihydrochloride
CAS Registry Number: 657-27-2
Percentage (%): >98% w/w
Impurities: Trace water, sodium chloride, minor organic acids from synthesis
Molecular Weight: 182.65 g/mol

First Aid Measures

Inhalation: Move exposed person to fresh air, monitor breathing, seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, wash affected area thoroughly with soap and water, seek medical advice if irritation continues
Eye Contact: Rinse cautiously with plenty of water for at least 15 minutes holding eyelids open, consult a physician if discomfort develops
Ingestion: Do not induce vomiting, rinse mouth with water, drink plenty of fluid, seek medical help if large quantities consumed or if feeling unwell
Most important symptoms: Minor irritation of mucous membranes, gastrointestinal upset if ingested

Fire-Fighting Measures

Extinguishing Media: Use water spray, dry chemical, CO2, or foam
Specific Hazards: No specific fire hazards, product is not flammable or explosive under normal conditions
Hazardous Combustion Products: Emits nitrogen oxides and hydrogen chloride under fire conditions
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Advice for Firefighters: Move containers from fire area, prevent runoff from entering drains

Accidental Release Measures

Personal Precautions: Avoid creating dust, ventilate area, use personal protective equipment such as gloves and dust mask
Environmental Precautions: Prevent large quantities from entering drains or waterways, inform authorities if necessary
Methods for Cleanup: Sweep up material and collect in properly labeled containers for disposal, wash spill site after material pickup
Containment: Contain spill with non-combustible absorbent materials, avoid generating airborne dust

Handling and Storage

Precautions for Safe Handling: Minimize dust generation, handle in well-ventilated area, avoid breathing airborne particles, wash hands after handling
Safe Storage Conditions: Store in tightly closed containers, keep in a cool, dry, well-ventilated location, protect from strong oxidizers and moisture
Incompatible Materials: Strong oxidizing agents, acids, bases
Storage Temperature: Ambient conditions recommended, avoid excessive heat and humidity

Exposure Controls and Personal Protection

Control Parameters: No established occupational exposure limits
Engineering Controls: Use adequate ventilation, fume hood or local exhaust if dust generated
Personal Protective Equipment: Protective gloves (nitrile or latex recommended), safety goggles, laboratory coat or apron, approved dust mask
Hygiene Measures: Do not eat, drink, or smoke during use, wash hands thoroughly after handling

Physical and Chemical Properties

Physical State: Crystalline powder
Color: White or almost white
Odor: Odorless
pH (solution): 4.5–6.0 (10% aqueous solution)
Melting Point: Decomposes above 260°C
Solubility in Water: 1000 g/L at 20°C
Vapor Pressure: Negligible
Boiling Point: Not applicable
Flash Point: Not flammable
Density: Approximately 1.24 g/cm³ at 20°C
Partition Coefficient: Not available
Evaporation Rate: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Reactivity: No reactive hazards identified
Conditions to Avoid: Excessive heat, moisture, strong acids, and oxidizers
Decomposition Products: Nitrogen oxides, hydrogen chloride released under extreme heating or fire
Polymerization: Will not occur under standard conditions

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: Oral LD50 (rat): >5000 mg/kg (low toxicity)
Irritation: Mild irritation possible if contact with skin or eyes, may cause throat discomfort if inhaled
Chronic Effects: Not classified as carcinogenic, mutagenic, or toxic to reproduction at levels of occupational exposure
Symptoms of Overexposure: Digestive upset, nausea, mild respiratory tract irritation
Sensitization: No sensitizing effects reported
Other Risks: Persons with kidney disorders may experience adverse effects if large quantities consumed

Ecological Information

Aquatic Toxicity: No evidence of toxicity for typical aquatic life at environmental concentrations
Persistence and Degradability: Readily biodegradable in soil and water
Bioaccumulation: Does not bioaccumulate in organisms
Mobility: Highly soluble and mobile in water, unlikely to persist
Other Environmental Risks: Excessive discharges may affect local nutrient balance

Disposal Considerations

Methods of Disposal: Dispose as non-hazardous chemical waste according to local, state, and federal regulations
Container Disposal: Triple-rinse containers, dispose of as per guidelines for chemical residue containers
Special Precautions: Avoid release to the environment, do not discharge into sewers or waterways in large amounts
Recommendations: Use licensed chemical disposal contractors for large-scale waste

Transport Information

UN Number: Not regulated as a dangerous good for transport
Proper Shipping Name: L-Lysine Dihydrochloride
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Marine Pollutant: Not classified as hazardous to the marine environment
Special Precautions: Avoid damage to packaging, keep dry during transport

Regulatory Information

US Regulatory Status: Not subject to reporting under SARA Title III, not listed in CERCLA, not listed as a hazardous chemical under OSHA
TSCA Listing: Listed in US Toxic Substances Control Act inventory
EU Regulations: Not listed as a hazardous substance under REACH, no specific hazard classifications
Labelling Requirements: No hazard label required
Other National Inventories: Included in most major chemical inventories worldwide (Canada DSL, Australia AICS, Japan ENCS, China IECSC)