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Chemical Name: L-Isoleucine
Synonyms: 2-Amino-3-methylpentanoic acid
CAS Number: 73-32-5
Molecular Formula: C6H13NO2
Molecular Weight: 131.17 g/mol
Product Use: Nutritional supplement, laboratory reagent, food additive
Supplier: Refer to local distributor or company providing this data
Contact Information: Phone and address of manufacturer or distributor
Emergency Contact: Regional poison control or emergency telephone
GHS Classification: Not classified as hazardous under GHS
Signal Word: None
Hazard Statements: No known significant effects or critical hazards
Precautionary Statements: Avoid unnecessary contact or inhalation of dust
Physical Hazards: May present dust hazard in powder form
Health Hazards: Inhalation of dust may cause respiratory irritation in sensitive individuals
Environmental Hazards: No significant environmental hazards identified
Component: L-Isoleucine
Purity: ≥98.5%
CAS Number: 73-32-5
Impurities: Trace amounts of related amino acids or processing residues (typically below regulatory concern)
Inhalation: Move person to fresh air; seek medical attention if symptoms occur
Skin Contact: Wash exposed area with soap and water; seek medical advice if irritation develops
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes; seek medical help if irritation persists
Ingestion: Rinse mouth with water, drink water to dilute; do not induce vomiting; seek medical advice if feeling unwell
Most Important Symptoms: Possible mild irritation to eyes, skin, and respiratory tract
Protection for First Responders: Use standard PPE including gloves and eye protection for handling spills or exposures
Suitable Extinguishing Media: Water spray, dry chemical, CO2, foam
Unsuitable Extinguishing Media: High-pressure water jet
Specific Hazards: Combustible dust; fine powder can form explosive mixtures with air
Hazardous Combustion Products: Carbon oxides, nitrogen oxides
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Firefighting Instructions: Avoid inhalation of smoke or fumes; prevent run-off entering water systems whenever possible
Personal Precautions: Avoid inhaling dust; wear gloves, eye protection, and mask if handling significant amount
Environmental Precautions: Prevent entry into drains, sewers, or water systems
Methods for Clean Up: Sweep up or vacuum spilled material using methods that avoid dust generation; place in waste container for disposal following local regulations
Reference to Other Sections: See “Exposure Controls and Personal Protection” for more on personal safety
Handling: Use in well-ventilated spaces; avoid dust formation; minimize exposure by using protective gear
Storage: Store in tightly sealed container in dry, cool place away from incompatible substances like strong acids, oxidizers
Specific End Uses: Only for dietary supplement or laboratory use as labelled; prevent use for non-listed applications
Conditions to Avoid: Excess heat, humidity, sources of ignition, static discharge in powder form
Exposure Limits: No occupational exposure limits established for L-Isoleucine
Engineering Controls: Provide adequate ventilation, such as local exhaust, to keep airborne concentrations low
Respiratory Protection: Dust mask or respirator if dust becomes airborne and ventilation is inadequate
Hand Protection: Chemical-resistant gloves
Eye Protection: Safety goggles or glasses
Skin Protection: Protective clothing advisable
Hygiene Measures: Wash hands thoroughly after handling; keep work clothes separate from personal clothing
Appearance: White crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH (1% solution): Approximately 6.0 to 7.0
Melting Point: 284–285°C (sublimes)
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Flammability: Not highly flammable but dust can present fire risk
Explosive Limit: Not determined; dust in air can be flammable
Vapor Pressure: Negligible
Solubility in Water: Approximately 41 g/L (at 20°C)
Partition Coefficient (log Pow): -1.34
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 200°C
Viscosity: Not applicable
Chemical Stability: Stable under normal conditions
Reactivity: Not highly reactive; can react with strong oxidizers
Possibility of Hazardous Reactions: No hazardous reactions expected under normal storage and handling
Conditions to Avoid: High temperatures, contact with strong oxidizing agents, exposure to moisture
Incompatibility: Strong acids, strong bases, and oxidizing substances
Hazardous Decomposition Products: May release carbon dioxide, carbon monoxide, nitrogen oxides upon decomposition
Acute Toxicity: Practically non-toxic; LD50 (oral, rat) > 5000 mg/kg
Chronic Toxicity: No adverse effects observed at nutritional doses
Skin Corrosion/Irritation: No significant effect
Serious Eye Damage/Irritation: Mild and reversible irritation possible
Respiratory Sensitization: Not expected
Germ Cell Mutagenicity: No evidence found
Carcinogenicity: Not classifiable as carcinogen
Reproductive Toxicity: Not indicated
STOT Single Exposure: No effects known
STOT Repeated Exposure: No effects known
Aspiration Hazard: Not applicable
Ecotoxicity: Not expected to pose environmental hazard at typical concentrations
Persistence and Degradability: Readily biodegradable
Bioaccumulation Potential: Low, log Kow indicates low potential
Mobility in Soil: High; likely to leach in soil due to high solubility
Other Adverse Effects: None known
Waste Treatment Methods: Dispose of in accordance with national and local regulations for non-hazardous organic waste
Disposal of Packaging: Triple rinse and recycle or dispose of containers per local guidance
Environmental Precautions: Prevent large quantities from entering surface waters or landfills without proper containment
UN Number: Not classified as a dangerous good for transport
Proper Shipping Name: L-Isoleucine
Transport Hazard Class(es): None
Packing Group: None
Marine Pollutant: No
Special Precautions: Avoid generating dust; store secure from moisture in transport
International Inventories: Listed on inventories such as TSCA (US), EINECS (EU), DSL (Canada), AICS (Australia)
Regulatory Status: Not regulated as hazardous under most chemical safety laws
SARA/OSHA Classification: Not listed as hazardous
California Proposition 65: Not listed
Other Regulations: Subject to regulation as food additive, supplement, or pharmaceutical ingredient according to jurisdiction
Labelling Requirements: Standard chemical label with identifier, hazard communication if not for retail or food use
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
