Product Name: L-Arginine Hydrochloride
Chemical Name: 2-Amino-5-guanidinopentanoic acid monohydrochloride
Synonyms: L-Arginine HCl, Arginine hydrochloride
Chemical Formula: C6H14N4O2·HCl
Molecular Weight: 210.66 g/mol
CAS Number: 1119-34-2
Supplier: Identified by manufacturer’s documentation
Recommended Use: Amino acid supplement, pharmaceutical intermediate
Emergency Contact: Refer to local regulations or company emergency number
GHS Classification: Not considered hazardous under GHS criteria
Physical Hazards: Non-flammable, non-explosive
Health Hazards: May cause mild skin and eye irritation upon contact; inhalation of dust can lead to mild respiratory issues
Environmental Hazards: Not classified as environmentally hazardous
Label Elements: No pictogram required; may be handled with basic precautions
Precautionary Statements: Avoid breathing dust; avoid contact with skin, eyes, and clothing; wash hands after handling
Unknown Acute Toxicity: Not available for complete mixture but can be extrapolated from ingredient data
Main Ingredient: L-Arginine Hydrochloride (CAS: 1119-34-2)
Concentration: >98% pure
Impurities: Trace amino acids and inorganic salts, less than 2% in total
Other Components: Water of crystallization, if present, does not substantially affect safety
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally; seek medical attention if irritation develops or persists
Skin Contact: Wash affected area with mild soap and water, remove contaminated clothing; medical attention for persistent irritation
Inhalation: Move to fresh air, support breathing as needed; consult a physician if symptoms, such as coughing or throat irritation, persist
Ingestion: Rinse mouth with water, do not induce vomiting, drink water to dilute; if symptoms occur or persist, seek medical advice
Medical Attention: Treat symptomatically, supportive care based on presentation
Suitable Extinguishing Media: Water spray, foam, dry powder, or carbon dioxide; avoid direct water jets
Unsuitable Media: None known for small laboratory quantities
Hazardous Combustion Products: Nitrogen oxides, carbon dioxide, carbon monoxide, and hydrogen chloride may be released in high heat
Protective Equipment for Firefighters: Wear full protective clothing and self-contained breathing apparatus
Special Firefighting Procedures: Cool containers with water spray to prevent overheating; prevent runoff into waterways
Fire/Explosion Hazards: Dust accumulation could theoretically present a weak explosion risk, though extremely low
Personal Precautions: Avoid dust formation, wear suitable gloves, eye/face protection, and dust mask
Environmental Precautions: Prevent large spills from entering drains, surface water, or soil
Containment: Clean up spill immediately with appropriate PPE, sweep up or vacuum in well-ventilated area
Cleanup Methods: Collect and place spilled product in a suitable, labeled container for disposal, wash area with water
Other Notes: Prevent airborne dust generation as much as possible
Safe Handling: Avoid creating and breathing dust, minimize exposure by using local exhaust ventilation; use personal protective equipment
Safe Storage: Store in original tightly closed container in a cool, dry, well-ventilated area away from incompatible substances like strong oxidizers
Hygiene Practices: Wash thoroughly after handling; do not eat, drink, or smoke in storage or use areas
Special Considerations: Protect from moisture and sources of contamination
Exposure Limits: No established regulatory occupational exposure limits; internal guidelines recommend minimizing exposure to airborne dust
Engineering Controls: Local exhaust ventilation, dust extraction if process generates dust
Respiratory Protection: Dust mask or particulate respirator when engineering controls do not keep exposure below nuisance levels
Eye Protection: Safety glasses with side shields or chemical safety goggles
Hand Protection: Nitrile or latex gloves
Skin Protection: Standard protective lab coat or apron
Workplace Hygiene: Routine hand washing, change contaminated clothing promptly
Appearance: White crystalline powder
Odor: Odorless or faint odor
Odor Threshold: Not applicable
pH (1% Solution): About 5 to 6
Melting Point: Decomposes before melting, above 228°C
Solubility in Water: Freely soluble, over 150 g/L at room temperature
Boiling Point: Not applicable (decomposes before boiling)
Vapor Pressure: Negligible at room temperature
Density: Approx. 1.2 g/cm³
Partition Coefficient (log Kow): Not determined
Evaporation Rate: Not applicable
Auto-Ignition Temperature: Not determined
Explosive Properties: Not explosive under normal conditions
Flash Point: Not applicable
Chemical Stability: Stable under normal temperatures and storage conditions
Possible Hazardous Reactions: No significant reactivity hazards expected
Incompatible Materials: Strong oxidizing agents, strong acids, and bases can react to produce heat or decomposition products
Decomposition Products: Thermal decomposition may lead to nitrogen oxides, carbon oxides, and hydrogen chloride
Conditions to Avoid: Excessive heat, moisture, and incompatible substances
Acute Toxicity: Oral LD50 in rats estimated >5,000 mg/kg, considered low toxicity
Skin Corrosion/Irritation: May cause mild irritation with prolonged exposure
Serious Eye Damage/Irritation: Dust may cause mild, reversible irritation
Respiratory or Skin Sensitization: Not expected to sensitize at low exposure, rare reports of allergic response in susceptible individuals
Repeated Dose Toxicity: No evidence of chronic toxicity based on available data; used therapeutically in controlled doses
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA
Mutagenicity: No data to suggest mutagenic effects
Other Data: In large quantities ingested, may cause gastrointestinal upset such as nausea, diarrhea, or abdominal pain
Ecotoxicity: No evidence of acute environmental hazard, ingredient is a natural amino acid used by living organisms
Persistence and Degradability: Readily biodegradable, expected to degrade rapidly in environment
Bioaccumulative Potential: Does not bioaccumulate in aquatic or terrestrial systems
Mobility in Soil: Expected to be highly mobile in water, but dissipates through breakdown
Other Adverse Effects: None known at standard levels of release
Waste Treatment Methods: Dispose of according to local, regional, and national regulations; typically as non-hazardous organic chemical waste
Disposal of Product: Small quantities can be diluted with water and disposed down the drain if local regulations permit; for larger quantities, consult environmental authorities
Disposal of Packaging: Triple rinse empty containers, recycle or dispose of as appropriate
Contaminated Packaging: Avoid reuse, treat as municipal waste if not heavily contaminated
UN Number: Not regulated as hazardous for transport
UN Proper Shipping Name: L-Arginine Hydrochloride
Transport Hazard Class: Does not have a hazard classification
Packing Group: Not applicable
Marine Pollutant: Not designated as such
Transport in Bulk: No specific bulk transport requirements
Special Precautions: During transport, keep tightly closed and protected from moisture and contamination
Regulatory Status: Not a hazardous substance or mixture according to OSHA Hazard Communication Standard or equivalent guidelines around the world
Inventory Listings: Listed in TSCA Inventory, REACH (EU), DSL (Canada), AICS (Australia), ENCS (Japan), and other major regulatory inventories
Labelling Requirements: No specific hazard symbol or risk phrase required; general chemical safety labeling applies
SARA 313 (US): Not subject to reporting
California Prop 65: Not listed
Workplace Controls: Basic industrial hygiene practices remain important
Other Regulations: Consult local, national, and international guidelines for environmental, health, and safety practices