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Product Name: Isobutyramide
Chemical Formula: C4H9NO
CAS Number: 563-83-9
Synonyms: 2-Methylpropanamide; 2-methylpropionamide
Recommended Use: Laboratory chemical, intermediate in organic synthesis
Manufacturer/Supplier: Chemical supplier details furnished on accompanying label
Contact Information: Emergency phone number appears on supplier website and safety information sheet
GHS Classification: Not classified as hazardous under GHS regulations
Health Hazard: Prolonged exposure may cause irritation to skin, eyes, and respiratory tract
Physical Hazard: May develop hazardous decomposition gases under fire conditions
Environmental Hazard: Harmful to aquatic life in large quantities
Signal Word: None recommended
Pictograms: None required
Precautionary Statements: Avoid contact with eyes or skin. Use in a well-ventilated area. Wash thoroughly after handling.
Substance: Isobutyramide
Chemical Identity: C4H9NO
Purity: Greater than 98%
Impurities and Stabilizing Additives: Trace organic contaminants may be present at levels insignificant for classification
Inhalation: Move person to fresh air immediately. Seek medical attention if breathing becomes difficult or symptoms persist.
Skin Contact: Wash exposed skin with soap and water for several minutes. Remove contaminated clothing.
Eye Contact: Flush eyes with plenty of water for 15 minutes, lifting eyelids occasionally. Seek medical advice if irritation develops.
Ingestion: Rinse mouth and seek medical help. Do not induce vomiting unless directed by a medical professional.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical powder, or carbon dioxide
Unsuitable Extinguishing Media: Avoid strong water jets that may spread spilled liquid
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective clothing
Special Information: Keep containers cool by spraying with water if possible. Prevent runoff into storm drains and waterways.
Personal Precautions: Use personal protective equipment recommended for handling. Ventilate area.
Environmental Precautions: Prevent further leakage or spillage if safe. Avoid discharge into drains or surface waters.
Methods for Cleaning Up: Absorb with inert material (e.g., sand, earth). Place in chemical waste container. Wash spill site after material pickup is complete.
Precautions for Safe Handling: Avoid inhalation, ingestion, and contact with eyes or skin. Use in a chemical fume hood if possible.
Conditions for Safe Storage: Store in a tightly closed container in a dry, cool, and well-ventilated area. Keep away from incompatible substances such as oxidizing agents and strong acids.
Incompatibilities: Avoid contact with strong oxidizers and acids that may cause violent reactions or decomposition.
Occupational Exposure Limits: No specific exposure limits established. Use good occupational hygiene practices.
Engineering Controls: Use local exhaust ventilation or chemical fume hood.
Personal Protective Equipment: Chemical-resistant gloves, protective safety goggles, lab coat, respiratory protection if airborne concentrations increase above recommended safe working levels.
Hygiene Measures: Do not eat, drink, or smoke during use. Wash hands thoroughly after handling.
Appearance: White crystalline solid or powder
Odor: Mild, characteristic odor
Odor Threshold: Not established
pH: Approximate neutral in aqueous solution
Melting Point: 122-124°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Evaporation Rate: Not determined
Flammability: Not classified as flammable
Vapor Pressure: Very low at room temperature
Vapor Density: Not determined
Relative Density: Approximately 1.07 g/cm³
Solubility in Water: Soluble
Partition Coefficient (log Kow): No data available
Autoignition Temperature: No data available
Decomposition Temperature: No data available
Viscosity: Not applicable (solid)
Chemical Stability: Stable under standard laboratory storage conditions
Reactivity: Not reactive under normal use or storage
Hazardous Reactions: Contact with strong oxidizing agents and strong acids may trigger hazardous reactions
Hazardous Decomposition: Carbon oxides, nitrogen oxides may form under fire or thermal degradation
Conditions to Avoid: Excessive heat, open flames, direct sunlight, incompatible chemicals
Incompatible Materials: Strong acids, oxidizing agents
Acute Toxicity: LD50 values not readily available for oral, dermal, or inhalation routes
Skin Corrosion/Irritation: May cause mild irritation following prolonged contact
Serious Eye Damage/Irritation: May cause temporary irritation
Respiratory or Skin Sensitization: No data available, but not expected based on structure
Germ Cell Mutagenicity: Not classified as mutagenic
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of reproductive toxicity from available data
Specific Target Organ Toxicity: Not identified
Aspiration Hazard: Not expected to be an aspiration hazard
Ecotoxicity: Data not available, but similar chemicals show low to moderate aquatic toxicity
Persistence and Degradability: Likely biodegradable under environmental conditions
Bioaccumulative Potential: Low based on water solubility and expected breakdown rate
Mobility in Soil: Mobile due to solubility in water and small molecular size
Other Adverse Effects: Release in large quantities may disturb aquatic life and microorganisms in water systems
Waste Treatment Methods: Dispose of according to local, regional, and national regulations
Product Disposal: Collect and store in a sealed container. Send to licensed hazardous waste disposal contractor.
Contaminated Packaging: Empty contents and triple rinse containers. Dispose of in accordance with regulations.
Special Precautions for Disposal: Avoid release to the environment, do not flush into drains, surface water, or soil
UN Number: Not regulated for transport
Proper Shipping Name: Non-hazardous chemical
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Environmental Hazards: Not considered marine pollutant
Special Transport Precautions: Keep sealed, avoid excessive heat and moisture during transport. Consult regulations for bulk or commercial quantities.
TSCA Inventory: Listed
EINECS/ELINCS: Listed
REACH Status: Exempted / Pre-registered
OSHA Hazards: Not considered hazardous under OSHA criteria
SARA Title III: Not listed as a hazardous substance or CERCLA reportable quantity
California Proposition 65: Not listed
Other Local Regulations: Consult local, state, and federal guidelines for handling and reporting requirements where applicable.
