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Material Safety Data Sheet – Iron Pyrophosphate

Identification

Product Name: Iron Pyrophosphate
Chemical Formula: Fe4(P2O7)3
Synonyms: Ferric Pyrophosphate, Iron(III) Pyrophosphate
CAS Number: 10058-44-3
Recommended Use: Food fortification, laboratory reagent, nutritional supplement
Manufacturer Details: Supplier’s address and contact available on company website or packaging
Emergency Phone: Local emergency contact or poison control center

Hazard Identification

GHS Classification: Not considered hazardous under GHS criteria for most handling conditions
Pictogram: No standard pictogram required for product at ambient temperature
Hazard Statements: May cause minimal irritation to eyes, skin, or respiratory system, particularly as a powder
Signal Word: None needed for regular handling
Precautionary Statement: Avoid generating dust; prevent inhalation of fine particles
Potential Health Effects: Mild mechanical irritation to eyes and skin; repeated overexposure by inhalation could irritate respiratory tract

Composition / Information on Ingredients

Chemical Name: Iron Pyrophosphate
CAS Number: 10058-44-3
Concentration: Typically ranges from 97% to 100% iron pyrophosphate
Impurities: Naturally includes trace elements such as silicon, calcium, or magnesium from raw materials or process, rarely above 0.5% combined

First Aid Measures

Eye Contact: Rinse carefully and thoroughly with plenty of clean water, keeping eyelids wide open. If irritation continues, seek medical advice.
Skin Contact: Remove contaminated clothing; wash skin with soap and water. Seek attention if a reaction begins to develop.
Inhalation: Move to an area with fresh air. Try to keep breathing slow and calm. If symptoms like shortness of breath develop, medical care becomes necessary.
Ingestion: If swallowed, rinse mouth with water and drink additional water to aid dilution. Medical observation advised if large amounts enter the body or irritation/other symptoms appear.
Note to Physicians: No specific antidote known for iron pyrophosphate. Treatment based on symptoms and support for respiratory, skin, or eye irritation as needed.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical foam, or CO2 extinguishers can control fires near storage or dust clouds; iron pyrophosphate itself is not flammable.
Hazardous Combustion Products: Heating may produce iron oxide and phosphorus oxides but no acutely toxic gases under most fire conditions.
Special Protective Equipment: Use protective gear including self-contained breathing apparatus and heat-resistant gloves for firefighters working in confined or smoke-filled environments.
Specific Hazards: If exposed to intense heat, fine dust could aggravate respiratory symptoms but does not sustain combustion.

Accidental Release Measures

Personal Precautions: Limit contact with dust using gloves, goggles, and particulate masks. Keep unnecessary personnel out of spill area.
Methods for Cleanup: Gently sweep or vacuum up spill, taking care not to generate airborne dust. Wet the powder lightly if possible to avoid dust clouds.
Environmental Precautions: Prevent bulk material from entering drains or water bodies. Sweep up small spills promptly for proper disposal.
Disposal Considerations: Place collected product in suitable containers for recycling or authorized landfill site.

Handling and Storage

Safe Handling Guidelines: Wear basic personal protection – gloves, eye protection, dust mask. Minimize dust generation by keeping container closed except when accessing product.
Storage Recommendations: Store in cool, dry, ventilated place. Keep iron pyrophosphate in sealed containers away from moisture and sources of contamination.
Incompatible Materials: Avoid strong acids or alkali materials, which may cause decomposition or reaction.
Hygiene Measures: Wash hands thoroughly after handling. Change out of work clothing before leaving work area.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limit for iron pyrophosphate as such, but general dust limits apply (<10 mg/m³ total dust recommended by OSHA/ACGIH guidelines).
Engineering Controls: Use local exhaust ventilation in enclosed areas where fine powder may be airborne. Maintain clean, hazard-free work surfaces.
Personal Protective Equipment (PPE): Use dust-resistant safety glasses, light protective gloves, lab apron, and particulate respirator where dust or spills are likely.
Environmental Exposure Controls: Avoid release of large quantities in open air, prevent entry into sewer or surface water.

Physical and Chemical Properties

Appearance: Fine, pale gray to yellowish white powder
Odor: Odorless
pH: Neutral to slightly basic in suspension (6.5–8.5, 10% aqueous solution)
Melting Point: Decomposes above 500°C; does not melt under normal atmospheric conditions
Solubility in Water: Practically insoluble at room temperature
Relative Density: Approximately 2.4–3.0 g/cm³
Vapor Pressure: Not applicable; solid at ambient temperature
Flash Point: Not flammable
Other Data: Stable under standard temperatures and pressures, powder form increases risk of transient airborne dust

Stability and Reactivity

Chemical Stability: Stable at normal ambient temperatures and storage conditions
Reactivity: Only reacts with strong acids (producing iron and phosphorus oxides, water) or strong bases
Conditions to Avoid: Prevent exposure to strong oxidizers or acids, and persistent moisture which may cause slow hydrolysis
Hazardous Decomposition Products: At high temperatures forms iron oxides, water vapor, and phosphorus oxides (under extreme heating such as fire)
Polymerization: Does not undergo hazardous polymerization

Toxicological Information

Acute Toxicity: Practically non-toxic by ingestion or skin contact in typical workplace environments; oral LD50 in lab animals exceeds several thousand mg/kg body weight
Irritation: Possible mild mechanical irritation to eyes or mucous membranes due to dust exposure
Sensitization: No evidence for allergic sensitization
Chronic Effects: No significant data showing chronic toxicity; accumulation in the human body is low under normal intake levels
Carcinogenicity: Not listed as a human carcinogen by IARC, NTP or OSHA
Mutagenicity: No mutagenic or genotoxic effects found in standard screening
Other Effects: Absorption of significant iron by ingestion (much higher than food supplement amounts) may risk iron overload syndrome in sensitive individuals

Ecological Information

Ecotoxicity: Not acutely harmful to aquatic life in standard laboratory testing
Persistence and Degradability: Stable in soil and water; not biodegradable but very low mobility due to poor solubility
Bioaccumulation Potential: Unlikely to bioaccumulate due to low solubility and poor absorption by aquatic organisms
Mobility in Soil: Minimal; remains in upper layers without leaching due to insolubility
Other Environmental Risks: Excessive dust in water can temporarily reduce oxygen exchange but does not poison aquatic organisms

Disposal Considerations

Waste Treatment Methods: Collect spill material and unwanted product for disposal as non-hazardous industrial solid waste
Disposal Recommendation: Deposit in landfill or according to local regulations for inorganic minerals; avoid flushing significant quantities to sewer
Environmental Precautions: Reuse or recycle where recovery options exist for iron salts in the industrial supply chain

Transport Information

UN Number: Not classified as a dangerous good under UN transport rules
Transport Hazard Class: Not regulated
Packaging Requirements: Strong containers or sacks; ensure tight seals to control dust
Special Precautions: Minimize movement of loose powder during transport. No temperature sensitivity; not flammable or reactive under standard shipping conditions

Regulatory Information

U.S. TSCA Status: Listed for commercial manufacturing and use
EU Classification: Not classified as hazardous under REACH or CLP Regulations
Food Additive Approval: Approved food fortifier under regulations of FDA (21 CFR 184.1301) and EFSA for allowed applications
Other International Listings: Registered in multiple jurisdictions for food and feed uses; always check national chemical inventory for current status
Labeling Guidelines: Safety data on packaging should include product name, hazard statements referencing dust potential, supplier address and emergency contact