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MSDS for Infant Bifidobacterium

Identification

Product Name: Infant Bifidobacterium
Synonyms: Bifidobacterium longum, Bifidobacterium infantis, probiotic strain
Recommended Use: Ingredient for infant supplements and food, research applications
Supplier Details: Name, address, emergency and non-emergency contact numbers for commercial or research distributor
Product Code: List individual batch or catalog ID for traceability
Relevant Identifying Numbers: CAS number, EC number, company internal reference codes

Hazard Identification

Classification: Non-pathogenic, considered safe for infant consumption, not a hazardous substance according to GHS or OSHA standards
Potential Hazards: May cause allergic reaction in extremely rare cases, respiratory irritation possible if powder is inhaled
Warning Symbols: No official hazard pictograms required
Precautionary Statements: Use in well-ventilated setting to avoid dust generation, avoid direct contact with eyes or open wounds
Potential: Not known to be carcinogenic, mutagenic, or teratogenic; not classified as an environmental hazard

Composition / Information on Ingredients

Chemical Name: Lyophilized Bifidobacterium powder
Main Components: Bifidobacterium spp. viable cells, skim milk powder/carriers (if present), trace excipients or stabilizers
Purity: Viable bacterial count standardized (CFU/g), non-viable biomass less than minimal threshold
Impurity Limits: Heavy metals, microbial contaminants such as Salmonella, E. coli below detectable limits per international food safety standards
Allergens: Presence of milk derivatives or other support matrix as stated on the supplier label

First Aid Measures

Eye Contact: Flush with plenty of clean water for at least 15 minutes. Remove contact lenses if present. Seek medical help if irritation persists.
Skin Contact: Wash exposed area with soap and water. Remove contaminated clothing. Use moisturizer if dryness or irritation occurs.
Inhalation: Move to area with fresh air. Rinse mouth and throat with water if powder inhaled. Get medical attention for continued respiratory discomfort.
Ingestion: Product is intended for oral use, but if large amounts consumed accidentally in a non-intended context, seek medical advice.
Long-Term Effects: No chronic health effects expected at standard levels for infants or adults

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, CO2, dry chemical, or foam extinguishers for surrounding fire.
Combustion Hazards: Organic powder can produce carbon dioxide, carbon monoxide, and minor amounts of other pyrolysis products
Protective Equipment: Fire fighters should use self-contained breathing apparatus and protective clothing to avoid inhaling smoke or dust
Unusual Fire Hazards: Dust may form explosive mixtures with air. Avoid strong sources of ignition or open flame during handling
Special Procedures: Collect contaminated firewater. Prevent subsequent run-off of large amounts into waterways

Accidental Release Measures

Personal Safety: Use appropriate PPE, such as gloves, safety goggles, and N95 masks in cases of large spills
Spill Clean-up: Gently sweep or vacuum up powder without generating dust. Avoid using compressed air
Environmental Precautions: Prevent product from entering drains, surface water, or soil in large quantities
Disposal of Waste: Place collected material in approved container for disposal in accordance with local regulations
Post-Cleaning: Wash hands and affected skin thoroughly after clean-up work

Handling and Storage

Handling: Wear gloves for extended handling. Minimize generation of dust, avoid breathing in airborne particles. Wash hands before eating or drinking. Keep work surfaces clean.
Storage Conditions: Store in original, sealed container at temperatures recommended by supplier—usually refrigerated (2-8°C) or as specified for freeze-dried preparations
Incompatible Materials: Store away from strong acids, oxidizers, and direct sunlight.
Shelf Life: Use by date or batch expiration date for full activity.
Long-Term Preservation: For research or bulk supply, some strains may be kept frozen (<-20°C) to maintain long-term viability

Exposure Controls and Personal Protection

Workplace Limits: No designated occupational exposure limit, standard good manufacturing practice applies
Engineering Controls: Use laboratory fume hood or air extraction to control dust for large-scale use
Personal Protective Equipment: Gloves, safety glasses, dust mask (recommended for bulk handling or for those with allergies)
Hygiene Measures: Wash hands after use, do not eat, drink, or smoke while handling product, change contaminated clothing promptly
Environmental Controls: Prevent release of large amounts into drains, surface water, or waste systems

Physical and Chemical Properties

Appearance: Off-white to light brown lyophilized or spray-dried powder
Odor: Faint, dairy-like or neutral odor
pH: Neutral to slightly acidic in suspension, depending on carrier matrix
Solubility: Disperses in water or milk, does not dissolve fully due to bacterial cell mass
Melting / Freezing Point: Not applicable; bacterial cells and carrier remain stable in recommended storage range
Density: Typical bulk density between 0.3–0.6 g/cm3 depending on drying process
Stability: Sensitive to repeated temperature fluctuations, exposure to moisture reduces cell count

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Excessive heat, repeated freeze-thaw cycles, high humidity
Incompatible Substances: Strong acids, strong oxidizing agents, quaternary ammonium disinfectants
Hazardous Decomposition: No hazardous decomposition products formed under normal use, combustion may generate carbon oxides
Polymerization: Does not occur. Product remains stable unless excessively handled outside recommended parameters

Toxicological Information

Acute Toxicity: No known toxic effects at levels intended for use. Long-standing safety record as probiotic in infant formulas
Chronic Toxicity: Not associated with carcinogenicity, teratogenicity, or reproductive toxicity
Potential Irritation: Direct contact with eyes may cause mild irritation. Rare risk of allergic response in those sensitized to dairy proteins or bacterial proteins
Sensitization: No evidence for widespread sensitization potential, but immunocompromised individuals should consult with a healthcare professional
Inhalation Effects: Respiratory irritation possible if powder inhaled in large quantities

Ecological Information

Ecotoxicity: Bifidobacterium is a natural inhabitant of the human gut, not considered a risk to aquatic or terrestrial organisms
Persistence and Degradability: Product is biodegradable; microorganisms break down in soil or wastewater environments
Bioaccumulation: No risk of bioaccumulation in wildlife or humans
Mobility: Product disperses in water, not persistent in the environment, non-toxic to plants or animals at expected concentrations
Other Adverse Effects: No known negative impacts on sewage treatment plants or microbial ecology

Disposal Considerations

Waste Treatment Methods: Dispose of as non-hazardous waste, in line with local regulations for food-grade biological material
Container Disposal: Rinse empty containers, then recycle or dispose according to local recycling programs
Environmental Precautions: Avoid uncontrolled release into environment. Small laboratory quantities can be disposed of in municipal trash when permitted.
Special Treatment: No special neutralization or hazardous procedures required due to non-toxic, non-pathogenic properties

Transport Information

UN Number: Not regulated as dangerous for transport
Hazard Class: Not classified for transport hazard under ADR, RID, IATA, DOT, IMDG codes
Packing Group: No packing group required
Labeling: No hazard labeling compulsory
Other Requirements: Keep product cool and dry during shipment. Commercial shipments often require temperature control for shelf life, so insulated packaging or cold chain recommended if stated by the supplier

Regulatory Information

Food and Drug Laws: Approved as a probiotic ingredient in infant food in EU, US, many Asian territories, GRAS (Generally Recognized as Safe) status for specified strains
Chemical Safety: Not classified as hazardous under OSHA Hazard Communication Standard or EU CLP Regulation
Biological Safety: Meets requirements for absence of pathogens and contaminants per international microbiological criteria
Workplace Safety Regulations: Follow applicable occupational health and hygiene laws for handling powders
Other Regulatory Listings: Product and formulations comply with Codex Alimentarius, FDA, EFSA regulations where required for infant and medical nutrition