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Product Name: Hordenine
Chemical Name: 4-(2-dimethylaminoethyl)phenol
Chemical Formula: C10H15NO
CAS Number: 539-15-1
Synonyms: N,N-Dimethyltyramine
Intended Use: Research, analytical reference, not for drug, cosmetic, or food use
Manufacturer: Laboratory or chemical supplier should be identified on packaging label
Emergency Contact: Refer to supplier safety department
GHS Classification: Acute Toxicity — Oral Category 4, Eye Irritation Category 2A, Skin Irritation Category 2
Hazard Pictogram: Exclamation Mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation
Precautionary Statements: Wash hands thoroughly after handling, do not eat or drink while using, avoid contact with skin and eyes
Potential Effects: Swelling, redness, allergic skin reaction, headache, nausea, agitation sometimes noted in susceptible persons
Target Organs: Skin, eyes, gastrointestinal tract
Substance: Hordenine (pure)
Content: >98% by weight
Impurities: Minor trace-level related phenethylamine derivatives (if manufactured synthetically)
Nature: Single chemical compound
Molecular Weight: 165.23 g/mol
General Advice: Get medical attention if symptoms develop or persist
Inhalation: Move person to fresh air immediately; seek medical attention if breathing problems appear
Skin Contact: Remove contaminated clothing, rinse skin with water and mild soap for a minimum of 15 minutes
Eye Contact: Rinse eyes gently under running water for several minutes, lift eyelids occasionally
Ingestion: Rinse mouth thoroughly; do not induce vomiting unless medical personnel recommend
Most Important Symptoms: Local irritation, dizziness, discomfort, redness in eyes, possible gastrointestinal irritation
Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Specific Hazards from Combustion: Emits carbon oxides, nitrogen oxides, toxic fumes if burned
Protective Equipment: Firefighters should wear self-contained breathing apparatus and flame-resistant clothing
Specific Methods: Cool adjacent containers with water spray to prevent pressure build-up
Unusual Hazards: Dust, fume, or decomposition product inhalation can be harmful in contained areas
Flash Point: >100°C (closed cup estimate)
Personal Precautions: Evacuate area, wear suitable respiratory equipment, prevent inhalation of dust
Environmental Precautions: Prevent spillage from reaching sewage or natural waterways
Cleanup Methods: Sweep up, avoid dust formation, place in labeled waste container; ventilate area well
Decontamination: Wash spill site with detergent and water after removal of material
Protective Equipment: Gloves, goggles, disposable particulate respirator if air becomes dusty
Precautions for Safe Handling: Avoid inhalation of powder, prevent contact with skin and eyes, use only with appropriate personal protection
Conditions for Safe Storage: Keep container tightly closed, store in a cool and dry location, keep away from incompatible substances such as strong oxidizers
Hygiene Practices: Wash thoroughly after handling, remove protective equipment before eating or resting
Special Storage Requirements: Store under inert gas or desiccator if high humidity might degrade product
Packaging Materials: High-density polyethylene or amber glass resistant to chemicals and humidity
Exposure Limits: No established OSHA or ACGIH exposure limit at this time
Engineering Controls: Work in a fume hood if possible; ensure adequate local ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles, laboratory coat, dust mask or NIOSH-approved respirator for airborne powder
Hygiene Measures: Change contaminated clothing promptly, wash hands at end of shifts and after handling
Environmental Controls: Do not allow to enter soil, sewers, or water systems
Appearance: White to off-white crystalline powder
Odor: Slight, amine-like scent
Odor Threshold: Not available
pH: No data for aqueous solution
Melting Point: 97-105°C
Boiling Point: Data not available
Flash Point: >100°C
Evaporation Rate: Not applicable for solid
Flammability: May be combustible at high temperature
Vapor Pressure: Negligible at ambient temperature
Solubility: Freely soluble in water, ethanol, methanol
Partition Coefficient (n-octanol/water): No data
Vapor Density: Not applicable
Relative Density: Not determined
Viscosity: Not applicable
Other Data: Decomposes before boiling at atmospheric pressure
Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts with strong oxidizers
Possibility of Hazardous Reactions: May form toxic gases if heated to decomposition
Conditions to Avoid: Excessive heat, exposure to moisture, open flame
Incompatible Materials: Strong oxidizing agents, acids
Hazardous Decomposition Products: Emits carbon oxides, nitrogen oxides, volatile organic fragments upon combustion or decomposition
Acute Toxicity: Oral LD50 (rat) estimated between 250–500 mg/kg; not well-characterized in humans
Skin Corrosion/Irritation: Can cause irritation on contact based on structural similarity to related phenols
Eye Damage/Irritation: Causes moderate to severe irritation
Respiratory Sensitization: No specific data available; avoid inhalation of dust
Skin Sensitization: Sensitization not documented but skin contact can trigger inflammation
Chronic Effects: No long-term toxicity data in animals or humans; related compounds can affect blood pressure and mood
Carcinogenicity: No evidence or classification as human carcinogen by IARC, NTP, ACGIH, OSHA
Potential Health Effects: Ingestion can lead to nausea, headache, rapid heartbeat in sensitive persons
Aquatic Toxicity: No specific data, low predicted risk at small scale, larger quantities can affect aquatic organisms due to amine functional group
Persistence and Degradability: Not rapidly biodegradable, moderate environmental persistence
Bioaccumulation: Low potential for bioaccumulation in aquatic organisms due to water solubility and metabolism
Mobility in Soil: Mobile in water; potential for leaching into ground water
Other Adverse Effects: Avoid release into environment, proper containment highly recommended
Waste Disposal Methods: Dispose via properly permitted chemical waste disposal contractor; do not pour down drain
Contaminated Packaging: Clean container with strong detergent under fume hood, recycle responsibly if possible
Additional Precautions: Follow all federal, state, and local environmental control regulations; include all safety labeling on containers for disposal
Recommendations: Use designated hazardous waste incinerator if available
UN Number: Not classified as dangerous under transport regulations for most jurisdictions
Proper Shipping Name: Not regulated
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Environmental Hazards: Not classified as environmentally hazardous for transport
Transport Precautions: Prevent package damage, keep containers sealed and secure, avoid temperature extremes
OSHA Status: Regulated as hazardous material through hazard communication standard
TSCA (Toxic Substances Control Act): Listed or data reported as permitted
SARA Title III Sec 313: Not specifically listed
California Proposition 65: Not listed
Other Global Inventories: Check specific country requirements; typically not a restricted substance under EU REACH, DSL/NDSL in Canada
Label Requirements: Ensure both GHS pictogram and hazard statements included on secondary containers
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
