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Product Name: Hesperidin
Chemical Formula: C28H34O15
Synonyms: Bioflavonoid, Hesperetin-7-O-rutinoside
CAS Number: 520-26-3
Intended Use: Antioxidant agent, supplement ingredient, research chemical
Supplier Information: Distribution centers usually list physical address, emergency and non-emergency contact numbers, and emails for technical support.
Recommended Use Restrictions: Not suitable for human or animal therapeutic use except as regulated; not to be inhaled, injected, or ingested unsupervised.
Classification: Not classified as a hazardous material based on GHS criteria.
Potential Hazards: Causes mild respiratory, skin, and eye irritation on direct contact; inhalation of dust may lead to mild respiratory discomfort in sensitive individuals.
Signal Word: None needed for typical laboratory and industrial settings.
Hazard Statements: May cause irritation to skin, eyes, and mucous membranes; avoid dust formation.
Pictograms: No pictogram required.
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; use gloves and lab coat or apron; operate in well-ventilated areas to minimize particulate exposure.
Component: Hesperidin
Purity: Commonly found above 90%, technical grade or higher.
Impurities: Trace bioflavonoids, glycoside derivatives, moisture below 3%.
Molecular Weight: 610.57 g/mol
Physical State: Fine crystalline powder.
Inhalation: Move person outside to fresh air. Support breathing if necessary. Seek medical attention for symptoms.
Skin Contact: Wash with plenty of soap and water. Remove contaminated clothing. Seek attention if irritation persists.
Eye Contact: Immediately rinse eyes with gentle stream of water for at least 15 minutes, eyelids apart. Remove contact lenses.
Ingestion: Rinse mouth with water, do not induce vomiting. Seek medical attention for symptoms.
Extinguishing Media: Dry chemical powder, foam, carbon dioxide, or water spray.
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, and possibly irritating organic vapors.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear to avoid smoke inhalation.
Fire/Explosion Risk: Powdered product may be combustible in large dust clouds; monitor for airborne dust.
Personal Precautions: Wear dust mask, gloves, eye protection. Ensure proper ventilation. Avoid direct contact with skin, eyes, and clothing.
Spill Cleanup Methods: Avoid creating dust; sweep up material and place it in designated waste containers. Wet-wipe area to minimize airborne particles. Dispose of sweepings per local, regional, and federal regulations.
Environmental Precautions: Do not release in drains or natural waterways. Notify authorities if large quantities enter water or soil.
Handling: Avoid contact with eyes, skin, and clothing. Use recommended PPE, work in fume hood or with local exhaust if possible. Do not eat, drink, or smoke while handling.
Storage: Keep container tightly sealed and stored in cool, dry place away from sunlight. Preferably store below 30°C, humidity-controlled environment. Keep away from incompatible materials such as strong acids or oxidizers.
Special Storage Compatibility: Do not store near sources of strong heat, oxidizing agents, and chemicals sensitive to organic dust.
Exposure Limits: No specific occupational exposure limits set for hesperidin.
Engineering Controls: Use with adequate ventilation, local exhaust, or containment systems to minimize dust.
Respiratory Protection: NIOSH-approved particulate respirator suggested if dust is generated.
Eye Protection: Safety goggles or face shield.
Skin Protection: Chemical-resistant gloves, long-sleeved clothing.
Hygiene Measures: Wash hands and face after handling, remove contaminated garments promptly.
Appearance: Pale yellow crystalline powder.
Odor: Nearly odorless.
Odor Threshold: Not available.
pH: 5.5–6.5 (1% solution).
Melting Point/Freezing Point: 258-262°C (decomposition).
Boiling Point: Not established.
Flash Point: Not applicable.
Evaporation Rate: Not relevant (non-volatile solid).
Flammability: Can burn as a fine powder.
Upper/Lower Explosive Limits: Data not established.
Vapor Pressure: Negligible at standard temperature.
Vapor Density: Not applicable.
Solubility: Sparingly soluble in water, soluble in methanol and ethanol.
Partition Coefficient (log Kow): 2.5–2.8 (estimated).
Auto-Ignition Temperature: Not available.
Decomposition Temperature: Decomposes above melting point.
Viscosity: Not relevant for powder.
Chemical Stability: Stable under recommended storage and use.
Thermal Decomposition: Exposure to heat above 200°C can result in breakdown producing irritants.
Conditions to Avoid: Extreme heat, moisture, and direct sunlight.
Incompatible Materials: Strong oxidizers, strong acids, alkali metals.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, volatile organics.
Reactivity Profile: Product doesn’t react violently with water or air.
Acute Toxicity (Oral LD50 – Rat): >5000 mg/kg (low acute toxicity).
Acute Toxicity (Dermal LD50): No data for skin lethality.
Inhalation Toxicity: Dust may cause respiratory irritation, coughing, or sneezing.
Skin Corrosion/Irritation: May cause slight irritation on repeated/prolonged contact.
Eye Damage/Irritation: Can cause mild eye irritation.
Chronic Toxicity: No known chronic health effects in humans.
Mutagenicity/Carcinogenicity: Not found to be mutagenic, no evidence of carcinogenicity reported.
Developmental/Reproductive Toxicity: No adverse reproductive or developmental effects noted in animal studies at expected doses.
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact.
Ecotoxicity: Very low aquatic toxicity; does not bioaccumulate significantly.
Persistence and Degradability: Readily biodegradable; natural breakdown in the environment.
Bioaccumulative Potential: Low, based on structure and water solubility.
Mobility in Soil: Moderate mobility predicted; not likely to contaminate groundwater appreciably.
Other Adverse Effects: No significant environmental hazards recorded. Release in large amounts could disrupt local flora and fauna.
Waste Treatment Methods: Dispose in accordance with local, regional, and national guidelines; treat as non-hazardous organic waste unless contaminated.
Contaminated Packaging: Rinse containers thoroughly before recycling or disposal; do not reuse containers.
Special Precautions: Avoid release into sewer or open water systems. Use authorized chemical disposal facilities.
UN Number: Not regulated for transport.
Proper Shipping Name: Hesperidin, non-hazardous material.
Transport Hazard Class: Not classified.
Packing Group: Not applicable.
Environmental Hazards: Not considered marine pollutant.
Special Precautions for Transport: Prevent heavy impacts and moisture exposure during shipping; standard labeling required.
OSHA Hazard Communication: Product does not meet criteria for hazardous classification under OSHA standards.
TSCA Inventory: Listed.
EU REACH Status: Registered substance; not requiring specific safety reporting at normal industrial volumes.
DSL/NDSL (Canada): Listed/Non-hazardous.
SARA 313, CERCLA, RCRA: Not regulated.
Proposition 65 (California): Not listed.
Other Local Requirements: Follow state/federal requirements as aspects may differ.
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
