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Material Safety Data Sheet (MSDS) for Glycogenase

1. Identification

Product Name: Glycogenase
Synonyms: Glycogen hydrolyzing enzyme
Recommended Use: Laboratory reagent, biochemical research
Supplier: Laboratory chemical supplier contact details required
Emergency Contact: Emergency phone number of responsible party or poison control
CAS Number: 9025-48-3
UN Number: Not assigned

2. Hazard Identification

Hazard Class: Not classified as a hazardous substance under GHS guidelines
Label Elements: No hazard pictograms or signal words assigned
Key Hazards: May cause mild skin or eye irritation in susceptible individuals, possible respiratory effects if inhaled as a dust, not expected to be mutagenic or carcinogenic
Medical Conditions Aggravated: Asthma, allergy, or respiratory sensitivity
Target Organs: None specifically identified; normal handling incurs low risk

3. Composition / Information on Ingredients

Chemical Identity: Glycogenase (Enzyme preparation, derived from microbial or animal sources)
Concentration: Pure enzyme preparation (typically >95%)
Other Ingredients: Stabilizers and buffer salts <5% (Sodium chloride, Tris-HCl, as examples)
Impurities: None with significant risk outlined in supplier documentation

4. First Aid Measures

Inhalation: Move person to fresh air, observe for respiratory discomfort, seek medical attention for persistent symptoms
Skin Contact: Wash with plenty of water and soap, remove contaminated clothing, seek medical care if irritation develops
Eye Contact: Rinse thoroughly with water for several minutes, remove contact lenses if present, continue rinsing, consult a healthcare provider if discomfort persists
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, consult a healthcare professional for assessment

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, foam
Unsuitable Extinguishing Media: None specifically identified, use common measures appropriate for fire in area
Special Hazards: Thermal decomposition may release carbon oxides and nitrogen oxides, otherwise low risk of hazardous combustion products
Protective Equipment: Firefighters wear self-contained breathing apparatus and protective suit

6. Accidental Release Measures

Personal Precautions: Wear gloves, safety goggles, and a lab coat, avoid creating dust, ventilate the area
Environmental Precautions: Prevent runoff into drains or water bodies
Cleanup Methods: Scoop or vacuum spilled powder, dampen residue to prevent dust, collect material in suitable containers for disposal
Decontamination: Wash spill area with mild detergent and water after cleanup
Handling Waste: Dispose of contaminated material as biological waste in accordance with regional practices

7. Handling and Storage

Handling: Avoid inhaling dust or direct skin contact, use in a well-ventilated environment with recommended PPE
Storage Conditions: Store tightly sealed at 2–8°C, avoid freezing unless provided as lyophilized powder, keep away from incompatible materials such as strong acids or oxidizing agents
Container Requirements: Use original packaging or compatible plastic/glass containers
Storage Incompatibility: Strong oxidizing agents, acids

8. Exposure Controls / Personal Protection

Occupational Exposure Limits: No specific TLV/PEL set for glycogenase
Engineering Controls: Use local exhaust ventilation for bulk handling, keep dust concentrations low, biosafety cabinet recommended for higher-risk operations
Personal Protective Equipment: Nitrile gloves, lab coat, safety goggles, dust mask or respirator (N95) if dust risk is present, avoid eating or drinking near work area
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing promptly

9. Physical and Chemical Properties

Appearance: White to off-white powder or lyophilized pellet, may appear granular or crystalline
Odor: Mild, not distinctive
pH (solution): 6.0–8.5 (when dissolved in appropriate buffer)
Melting Point/Freezing Point: Not applicable, enzyme deactivates at higher temperatures
Solubility: Freely soluble in water and common buffer solutions
Boiling Point: Not applicable
Flash Point: Not flammable
Vapor Pressure: Not relevant
Relative Density: Approximately 1.2 g/cm3 (powder)
Stability: Stable under recommended storage and handling conditions

10. Stability and Reactivity

Chemical Stability: Stable under normal temperature and pressure, may degrade if exposed to heat, moisture, or incompatible substances
Reactivity: Not reactive under standard laboratory conditions, avoid contamination with strong acids, bases, or oxidizers
Hazardous Decomposition: Possible release of carbon oxides and nitrogen oxides if severely heated or combusted
Polymerization: Not known to occur

11. Toxicological Information

Acute Toxicity: Not expected to be toxic in small, controlled exposures, data on significant ingestion lacking
Skin/Eye Irritation: Mild irritation can occur from dust exposure
Inhalation: May cause respiratory tract discomfort, coughing, or allergic response in sensitive individuals
Chronic Effects: Sensitization possible after repeated skin or respiratory exposure
Carcinogenicity: No evidence found linking glycogenase to cancer
Mutagenicity: No mutagenic potential observed in standard assays
Reproductive Toxicity: No negative reproductive effects reported from occupational or experimental exposure

12. Ecological Information

Ecotoxicity: Not expected to be harmful to aquatic or terrestrial environments at typical laboratory or production scale concentrations
Persistence/Degradability: Readily biodegradable, enzyme breaks down rapidly under environmental conditions
Bioaccumulation: Not anticipated to bioaccumulate due to protein nature and degradation
Mobility: Water soluble, disperses in water with no expected negative ecological effects
Other Adverse Effects: No ozone depletion, greenhouse effect, or specialized hazard expected

13. Disposal Considerations

Disposal Methods: Place in appropriately labeled biological waste, incinerate or landfill following local, state, and federal regulations
Contaminated Packaging: Rinse containers, dispose as regular chemical waste according to institutional policies
Special Precautions: Avoid release to groundwater, sewers, or open environment, consult with environmental manager on large-scale disposals

14. Transport Information

UN Number: Product does not meet criteria for dangerous goods classification
Transport Hazard Class: Not regulated as hazardous for road, air, or sea
Packing Group: Not required
Environmental Hazards: None identified
Special Precautions: Keep sealed, cool, and protected from direct sunlight during shipment
Label: Standard shipping label for laboratory chemicals

15. Regulatory Information

OSHA: Not listed as hazardous under OSHA Hazard Communication Standard
TSCA Inventory: Not listed, exemptions for research and development preparations
SARA Title III: No substances reportable under Sections 302, 304, 313
REACH Status (EU): Exempt, or not subject to registration for specific research use
WHMIS Classification (Canada): Not classified as controlled product
Other: No special environmental, safety, or health regulations enforceable for standard use and storage