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Material Safety Data Sheet (MSDS) for Gluconolactone

Identification

Product Name: Gluconolactone
Synonyms: D-Glucono-1,5-lactone, GDL, Gluconic acid lactone
Chemical Formula: C6H10O6
CAS Number: 90-80-2
Manufacturer: Please refer to packaging label for detailed manufacturer information.
Recommended Use: Used as an acidity regulator in foods, chelating agent in cosmetics, and pharmaceutical excipient.
Emergency Contact: Local poison control center or emergency services.

Hazard Identification

Classification: Product does not present major hazards under normal conditions.
GHS Label Elements: Not classified as hazardous according to GHS guidelines.
Health Risks: Dust may irritate respiratory tract, eyes, or skin for some users.
Environmental Hazards: Low hazard for environment under standard handling.
Precautionary Statements: Avoid creating dust clouds, use adequate ventilation, wash hands thoroughly after handling.

Composition / Information on Ingredients

Chemical Name: Gluconolactone
Concentration: Greater than 98% purity
Impurities: Small traces of gluconic acid possible
Other Components: Not present in hazardous amounts or concentrations

First Aid Measures

Inhalation: Move affected person to fresh air. If symptoms develop, seek medical attention.
Skin Contact: Wash area thoroughly with soap and water. Remove contaminated clothing.
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes and seek medical advice if irritation persists.
Ingestion: Rinse mouth with water. Do not induce vomiting. Contact poison control center if large quantity consumed or symptoms appear.
Advice to Physician: Treat according to symptoms.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, CO2.
Unsuitable Extinguishing Media: Direct water jet on powder may cause splattering.
Combustion Hazards: Product may release carbon oxides under fire conditions.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing.
Special Procedures: Avoid breathing dust or smoke during fire response. Cool containers with water spray.

Accidental Release Measures

Personal Precautions: Avoid breathing dust, provide good ventilation, and use personal protective equipment such as gloves and dust masks.
Environmental Precautions: Prevent large amounts of powder from entering soil or water systems.
Methods for Containment and Clean-Up: Sweep up carefully to prevent creating dust cloud, collect in suitable waste containers for disposal, clean residue with moist absorbent material.

Handling and Storage

Safe Handling: Avoid dust formation, use with adequate local exhaust ventilation, do not eat, drink, or smoke during handling.
Hygiene Measures: Wash hands thoroughly after handling, keep work area clean.
Storage Conditions: Store in a cool, dry, and well-ventilated place. Keep container tightly closed to avoid moisture uptake.
Incompatible Materials: Strong oxidizing agents, strong acids.
Packaging: Use food-grade or chemical-resistant packaging, avoid metal containers for prolonged storage.

Exposure Controls and Personal Protection

Engineering Controls: Use adequate local exhaust ventilation, process enclosures if possible.
Personal Protection: Wear safety glasses with side shields, chemical-resistant gloves, and protective clothing if large amount handled.
Respiratory Protection: NIOSH-approved dust mask or respirator may be necessary for sensitive individuals or dusty atmospheres.
Occupational Exposure Limits: No established limits, but minimize prolonged or repeated exposure.

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Molecular Weight: 178.14 g/mol
Odor: Odorless
pH (1% solution): 2.0 – 3.0
Solubility: Freely soluble in water
Melting Point: Decomposes at approximately 150°C
Boiling Point: Not applicable (decomposes before boiling)
Density: 1.65 g/cm³
Flash Point: Not flammable
Partition Coefficient (n-octanol/water): Not available
Vapor Pressure: Not applicable for solid form

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions.
Reactivity: Reacts with strong oxidizing agents and acids.
Conditions to Avoid: Prolonged exposure to moisture and elevated temperature.
Hazardous Decomposition Products: May release carbon monoxide and carbon dioxide from thermal decomposition.
Polymerization: Does not occur.

Toxicological Information

Acute Toxicity: Low acute oral toxicity in mammals; high ingestion in animals can cause gastrointestinal discomfort.
Skin Irritation: Non-irritant to most individuals, but sensitive users can experience mild irritation.
Eye Irritation: Can cause temporary discomfort.
Sensitization: Not expected to cause skin sensitization.
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity.
Inhalation: Large dust quantities may cause respiratory irritation.

Ecological Information

Aquatic Toxicity: Low toxicity for aquatic organisms; readily biodegradable.
Persistence and Degradability: Rapidly breaks down by microorganisms.
Bioaccumulation Potential: Not likely to bioaccumulate in aquatic environments.
Mobility in Soil: Moves easily in soil when dissolved in water.
Soil and Water Effects: Low risk to most natural systems, no known adverse effects at typical usage levels.

Disposal Considerations

Disposal Methods: Dispose of small amounts as non-hazardous solid waste.
Larger Volumes: Use landfill or incineration according to local regulations.
Recycling: Not practical for spent product.
Packaging Disposal: Rinse packaging and recycle if possible; otherwise, follow local requirements for disposal of chemical packaging.

Transport Information

UN Number: Not regulated.
Proper Shipping Name: Gluconolactone.
Transport Hazard Class: Non-hazardous for all transport modes.
Packing Group: Not applicable.
Environmental Hazards: Not classified as environmentally hazardous.
Special Precautions: Avoid moisture during transport to prevent product caking.

Regulatory Information

US TSCA: Listed.
EU REACH: Exempt or registered depending on tonnage.
GHS Compliance: Meets GHS safety and health requirements.
Food Additive Status: Approved by FDA and EFSA for food use.
Labeling Requirements: Standard labeling for non-hazardous chemical, avoid using for purposes other than recommended application.
Other Regulations: Ensure compliance with cosmetic and pharmaceutical regulations where applicable.