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West Ujimqin Banner, Xilingol League, Inner Mongolia, China
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Product Name: Glucoamylase Enzyme Preparation
Common Uses: Starch conversion in food processing, alcohol fermentation, brewing, industrial applications
Synonyms: Amyloglucosidase, Glucan 1,4-α-glucosidase
Manufacturer: Enzyme production facility located in regulated industrial sector, with quality and safety certifications
Emergency Contact Number: National Poison Control Center, local emergency services, or specified company safety desk
Recommended Use Restrictions: Only handled by trained personnel following safety guidelines
Classification: Non-flammable, non-toxic, classified under non-hazardous by OSHA and GHS for general handling, but can be respiratory sensitizer
Major Health Hazards: Allergy risk in some workers after prolonged inhalation of dust or aerosols, mild skin and eye irritation for individuals with sensitivity, no long-term chronic effects in usual conditions
Pictograms: Exclamation mark for skin/eye/respiratory irritation
Signal Words: Caution for sensitive individuals or those with known allergies to proteins
Precautionary Statements: Wear protective equipment, avoid creation of airborne dust, use in well-ventilated areas, avoid direct contact with eyes or damaged skin
Main Ingredient: Glucoamylase enzyme (EC 3.2.1.3) produced from Aspergillus niger or genetically modified organisms
Concentration: 10-50% active enzyme protein (depending on product specification)
Other Components: Food-grade stabilizers, sodium chloride, carbohydrates (e.g., dextrins or maltodextrins), water (if liquid)
Substance Identity Numbers: CAS: 9032-08-0 for Glucoamylase
Impurities: No hazardous impurities above regulatory disclosure levels, trace fermentation byproducts
Inhalation: Move person to fresh air, monitor for symptoms such as coughing, sneezing, or wheezing, seek medical attention if shortness of breath or chest discomfort develops
Skin contact: Rinse with clean running water, use soap and water to remove residues, medical advice needed for persistent irritation or allergies
Eye contact: Rinse eyes gently with water for several minutes, remove contact lenses if present and easy, continue rinsing, seek prompt medical advice in case of redness, swelling, or pain
Ingestion: Rinse mouth, drink water to dilute, seek medical evaluation if large amounts swallowed or if symptoms develop
Flammability: Not considered flammable, will not support combustion under normal conditions
Suitable Extinguishing Media: Use water spray, dry chemical, CO2, or foam for surrounding fires
Special Hazards: Enzyme powders can form fine dusts, potential risk for dust explosions in heavily contaminated air, avoid dry sweeping
Protection for Firefighters: Full protective gear, suitable respirator if risk of dust exposure, self-contained breathing apparatus in case of heavy smoke
Decomposition Products: None expected under normal conditions, standard combustion products like CO2, CO
Personal Precautions: Wear gloves, goggles, and dust mask to reduce skin and respiratory exposure, ventilate area
Spill Cleanup: Avoid creating dust clouds, use damp methods or vacuum with HEPA filter for dry spills, absorb liquid with inert material and collect
Environmental Precautions: Prevent entry into drains, soil or waterways, collect all waste for proper disposal
Reporting Requirements: Report large spills to environmental authorities as required by local regulations
Handling: Use measures to avoid aerosol and dust generation, do not breathe dusts, handle in well-ventilated areas
Prohibited Practices: Do not eat, drink, or smoke during use, keep product away from food and beverages
Storage: Store in original, tightly sealed containers, in cool, dry area protected from direct sunlight, avoid high humidity and temperatures
Separation: Keep away from incompatible materials, especially strong acids or oxidizers, laboratory and industrial guidelines apply
Exposure Limits: No OSHA PEL or ACGIH TLV specific for glucoamylase, suggested workplace dust limit: 0.00006 mg/m3 (enzyme protein, as recommended for allergenic enzymes)
Engineering Controls: Use local exhaust ventilation, maintain effective air changes where powder handled
Personal Protective Equipment (PPE): Wear goggles, suitable gloves, dust mask or respirator (P2 or N95 minimum for powders), lab coat or coverall, avoid direct skin contact
Hygiene Measures: Wash hands after handling, launder work clothing regularly to avoid buildup of enzyme proteins
Appearance: Off-white to light yellow powder or liquid solution, faint sweet odor
pH: 4.0–7.0 in aqueous solution depending on formulation
Solubility: Soluble in water, insoluble in organic solvents
Melting Point: Not applicable (decomposes before melting)
Boiling Point: Not applicable
Vapor Pressure: Non-volatile
Specific Gravity: 1.1–1.3 (liquid), bulk density 500–800 kg/m3 (solid)
Stability: Stable under recommended storage, loss of activity above 50°C
Chemical Stability: Stable under normal storage and handling, retains activity for shelf life if kept dry and out of heat
Reactivity: No hazardous reactions anticipated under normal conditions
Incompatible Materials: Strong acids, bases, oxidizing agents may denature protein components, do not mix with reactive chemicals
Hazardous Decomposition Products: Thermal decomposition leads to water vapor, carbon dioxide, carbon monoxide
Polymerization: Will not occur
Acute Toxicity: Not acutely toxic by oral, dermal, or inhalation routes at expected exposure levels
Irritation: Mild eye and skin irritant in sensitive individuals, respiratory exposure can cause sensitization and asthmatic reactions with repeated exposure in certain workers
Sensitization: Recognized respiratory allergen in workplace settings, symptoms include runny nose, cough, wheezing after repeated inhalation
Long-Term Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity in animal studies or workplace reviews
Relevant Animal Data: Oral LD50 in rats >2,000 mg/kg (low toxicity), inhalation LC50 not established
Aquatic Toxicity: Not hazardous to aquatic life at expected release concentrations, rapidly biodegradable
Persistence and Degradability: Product breaks down naturally in the environment, enzyme protein and carrier materials degraded by soil or wastewater microorganisms
Bioaccumulation Potential: Low, enzyme proteins hydrolyzed and consumed by natural biota
Soil Mobility: Moderate mobility if released into environment, product does not persist or bioaccumulate
Other Harmful Effects: No known adverse ecological effects reported by environmental monitoring data
Disposal Methods: Small quantities can be flushed with excess water into sewage or wastewater treatment consistent with local rules, larger amounts collected by waste contractor
Contaminated Packaging: Dispose of in accordance with local, regional, and national regulations, rinse thoroughly before recycling or disposal
Special Requirements: Avoid generating airborne dust during disposal, do not release enzyme-containing cleaning water into streams or open soil
Regulatory Requirements: None beyond general non-hazardous waste management for most regions
UN Number: Not classified as dangerous goods under UN Model Regulations, IMDG, or IATA
Proper Shipping Name: Not regulated
Packing Group: Not assigned
Special Precautions: Avoid exposure of cargo to moisture or excessive heat to preserve enzyme activity
Labeling Requirements: None for land, sea, or air transport when packed securely in standard packaging
OSHA Status: Not listed as hazardous substance, considered non-hazardous for workplace safety standard purposes
TSCA Inventory: Components listed or exempt
EU Reach: No chemical registration requirement for enzyme proteins in current quantities and uses
GHS Label Elements: Not classified as hazardous by the Globally Harmonized System, caution for sensitization remains
Other Regulations: FDA-approved for use in food processing within specified limits, meets FAO/WHO enzyme specifications for recommended uses
Workplace Continuous Surveillance: Advised for workers with known allergies to enzymes, respiratory health monitoring following local guideline for enzyme-using industries
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
