Product Name: Ginkgo Biloba Extract
Chemical Name: Ginkgo Biloba Leaf Extract
Synonyms: Maidenhair Tree Extract
Manufacturer: Comprehensive supplier information should be included on a company-specific sheet
Recommended Use: Ingredient in dietary supplements, herbal products, pharmaceutical applications
CAS Number: 90045-36-6
Emergency Telephone: Include local or manufacturer-provided emergency contact number
Classification: Eye irritant, skin sensitizer, possible respiratory tract irritant
Risk Phrases: Irritating to eyes, respiratory system, and skin; may cause allergic reaction on sensitive skin
Hazard Symbols: Exclamation mark (GHS07)
Routes of Exposure: Inhalation, skin and eye contact
Potential Health Effects: Short-term exposure may cause irritation or rash; inhaling dust causes coughing or throat discomfort; ingestion in large quantities may produce digestive upset
Chronic Effects: Prolonged exposure may trigger allergies, dehydration, or stomach issues
Environmental Hazards: Potential threat to aquatic life if released in large volumes
Main Ingredient: Ginkgo Biloba Leaf Extract (typically standardized to 24% flavone glycosides, 6% terpene lactones)
Active Compounds: Flavonoids (quercetin, kaempferol), Terpenoids (ginkgolides, bilobalides)
Other Components: Carriers such as maltodextrin (if present), trace moisture, minor plant-derived compounds
Impurities: None expected under typical manufacturing conditions
Concentration Range: Extracts used range from 50:1 to 70:1, dependent on supplier specification and end use
Inhalation: Move to fresh air. If symptoms persist, seek medical attention. Coughing or throat irritation may occur if dust inhaled.
Skin Contact: Wash affected area with soap and water. Remove contaminated clothing. Seek medical evaluation for persistent irritation or rash.
Eye Contact: Rinse thoroughly with plenty of water for several minutes. Remove contact lenses if present and continue rinsing. Obtain medical help for redness or vision changes.
Ingestion: Rinse mouth with water. If large amounts consumed or gastrointestinal symptoms develop, get medical attention.
Most Important Symptoms: Skin or eye irritation, dry cough, allergic reaction
Notes to Physician: Treat symptomatically, monitor for delayed respiratory or allergic reactions
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, or water spray
Unsuitable Media: Strong water jets (may spread powder)
Fire Hazards: May form combustible dust concentrations in air
Combustion Products: Carbon monoxide, carbon dioxide, possible organic fumes
Special Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Firefighting Procedures: Avoid dust build-up; cool fire-exposed containers
Personal Precautions: Evacuate unnecessary personnel; use appropriate protective equipment to avoid inhalation and contact
Environmental Precautions: Prevent large quantities from entering sewers, drains, or water sources
Clean-up Methods: Sweep or shovel material into suitable containers for disposal; avoid generating airborne dust
Spill Containment: Dampen spilled powder slightly to minimize airborne particulates
Handling: Use local exhaust ventilation to control dust exposure; avoid breathing dust or contact with skin and eyes
Storage Requirements: Store in cool, dry, well-ventilated area in a tightly sealed container; keep away from sources of ignition, strong acids, bases, or oxidizing agents
Incompatible Materials: Strong oxidizing agents may trigger reactions; moisture and direct sunlight reduce shelf life and potency
Hygiene Practices: Wash hands after handling; do not eat, drink, or smoke in storage or use areas
Engineering Controls: Use local ventilation or extraction systems to manage dust
Respiratory Protection: NIOSH-approved dust masks recommended during bulk handling
Hand Protection: Use chemical-resistant gloves
Eye Protection: Safety glasses with side shields provide reliable protection
Skin Protection: Wear long sleeves or laboratory coats to reduce skin exposure
Exposure Limits: No OEL or TLV established specifically for this extract; keep dust below general nuisance dust levels (typically 10 mg/m³)
Appearance: Light brown to yellowish-brown powder
Odor: Mild, characteristic herbal aroma
Melting Point: Not applicable (decomposes)
Boiling Point: Not available
Shelf Life: Up to two years under ideal storage
Solubility: Partially soluble in water, more soluble in alcohol
Bulk Density: Typical range 0.40 – 0.60 g/cm³
pH Value: 4.0–7.0 (1% solution in water)
Flash Point: Not established
Vapor Pressure: Not applicable
Flammability: As an organic powder, can form explosive dust clouds if dispersed in air
Chemical Stability: Stable under recommended storage
Reactivity: No hazardous reactivity expected under normal conditions
Hazardous Decomposition: Produces carbon oxides and organic fumes if burned
Incompatible Materials: Strong oxidizing substances, strong acids and bases
Polymerization: Will not occur under routine conditions
Conditions to Avoid: Moisture, excess heat, direct sunlight, open flames
Acute Oral Toxicity: Studies point to low acute oral toxicity (LD50 in rats above 2,000 mg/kg body weight)
Inhalation Toxicity: Inhaling dust causes transient discomfort; no chronic toxicity found at typical exposure
Skin Irritation: Mild, reversible irritation possible, rare allergic reaction reported
Eye Contact: Causes short-term irritation due to dust particles
Sensitization: Potential risk of allergy with long-term contact
Chronic Exposure: No evidence of carcinogenicity, teratogenicity, or reproductive toxicity in standard studies
Medical Conditions Aggravated: Pre-existing respiratory allergies, asthma, or skin hypersensitivity
Ecotoxicity: Such extracts usually break down in soil; risk to aquatic organisms increases with concentrated spills
Persistence: Decomposes naturally as an organic material
Bioaccumulation: No evidence for significant build-up in common aquatic species
Mobility: Product unlikely to reach groundwater under typical use
Environmental Fate: Rapid biodegradation in the environment; not considered a persistent organic pollutant
Aquatic Toxicity: At high concentrations, plant compounds may affect aquatic species, but standard use poses minimal risk
Waste Disposal: Gather and place excess material in containers for landfill; follow local regulations for organic chemical waste
Container Disposal: Rinse empty containers and arrange for municipal waste pickup
Incineration: Permitted where facilities exist; release controlled combustion gases only in approved incinerators
Precautions: Avoid uncontrolled release; prevent dispersal of dust to reduce environmental impact
Regulatory Compliance: Always refer to regional, national, and local waste disposal requirements
UN Number: Not regulated as hazardous under UN transport rules
Transport Hazard Class: Not classified
Packing Group: No assignment, non-hazardous
Special Precautions: Keep container sealed, dry, and away from food cargo
Labeling: No special transport marks necessary for road, rail, air, or sea, following current legislation
Shipping: Use sturdy, sealed containers; avoid creating airborne dust during loading/unloading
Global Chemical Inventories: Present on most international inventories as a natural extract
Label Requirements: Must reflect hazard identification under OSHA, EU CLP, GHS rules
Food, Drug, and Cosmetic Laws: Classified as a dietary supplement ingredient in many regions; restrictions apply in pharmaceuticals
Worker Protection: Employers must provide training and safety data sheets per OSHA (USA) or analogous local laws
Specific Standard References: Conforms to REACH (EU), TSCA (US), and other international chemical safety legislation where marketed
Restrictions: Not approved for use in products targeting children or pregnant women absent additional safety data
Additional Reporting: Report large releases as required by local environmental laws