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Product Name: Genistein
Chemical Name: 4',5,7-Trihydroxyisoflavone
CAS Number: 446-72-0
Molecular Formula: C15H10O5
Molecular Weight: 270.24 g/mol
Synonyms: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Supplier Details: Manufacturer and distributor contact information, including phone, address, and emergency contact numbers should be located directly on the shipment documents.
Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity-single exposure Category 3
GHS Label Elements: Exclamation mark symbol
Hazard Statements: Causes serious eye irritation; may cause respiratory irritation; may cause skin irritation; harmful if swallowed in large quantities
Precautionary Statements: Avoid breathing dust or powder; wash hands thoroughly after handling; use only outdoors or in a well-ventilated area; wear protective gloves, eye protection, and face mask.
Chemical Name: Genistein
Concentration: 98-100% pure
CAS Number: 446-72-0
Impurities: Trace levels of related isoflavones or residual solvents possible depending on synthesis route; typically less than 2% total impurities
Eye Contact: Rinse with clean water for at least 15 minutes, lift upper and lower eyelids occasionally, seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with soap and water, seek medical attention if skin irritation develops
Inhalation: Move affected person to fresh air, supply oxygen if breathing is difficult, seek medical attention if symptoms develop
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, seek medical attention for assessment
Suitable Extinguishing Media: Use dry chemical, CO₂, foam, or water spray
Specific Hazards: Emits toxic fumes of carbon monoxide and carbon dioxide under fire conditions
Protective Equipment for Firefighters: Use self-contained breathing apparatus (SCBA) and full protective gear
Special Precautions: Avoid inhalation of combustion gases, keep containers cool with water spray if exposed to fire
Personal Precautions: Wear appropriate personal protective equipment including gloves and eye protection, avoid inhaling dust
Emergency Procedures: Evacuate area, provide adequate ventilation
Environmental Precautions: Prevent further leakage or spillage if safe to do so, avoid letting the material reach drains or watercourses
Methods for Clean-Up: Sweep spilled material into leak-proof containers, avoid generating dust, clean contaminated surface thoroughly
Handling: Employ effective local exhaust ventilation, avoid creating dust, handle only with proper personal protective equipment, wash hands before eating or drinking
Storage: Keep tightly closed in a dry, cool, well-ventilated place, avoid direct sunlight, separate from incompatible materials including strong oxidizers, acids, and bases, store at recommended temperature range, label containers clearly with hazard information
Exposure Limits: No specific occupational exposure limits established, recommend keeping exposure as low as reasonably achievable
Engineering Controls: Use local exhaust ventilation, process enclosures, or other engineering controls to keep airborne levels below recommended exposure limits
Personal Protection: Wear safety glasses or chemical splash goggles, suitable chemical-resistant gloves, lab coat or protective clothing, dust respirator if exposure limits are approached
Physical State: Crystalline powder
Color: Off-white to pale yellow
Odor: Odorless
pH (1% solution): Slightly acidic
Melting Point: 297-298°C (566-568°F)
Boiling Point: Decomposes before boiling
Solubility: Poorly soluble in water, soluble in ethanol, DMSO, acetone, and alkaline solutions
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Pow): 2.44
Flash Point: Not applicable
Density: Approximately 1.4 g/cm³
Chemical Stability: Stable under normal handling and storage conditions
Conditions to Avoid: Exposure to excessive heat, light, moisture
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, phenolic fumes
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Low oral toxicity in animal studies (oral LD50 in rats > 5000 mg/kg), may cause discomfort if ingested in large amounts
Chronic Effects: Not classified as carcinogenic, mutagenic, or reproductive toxin by current standards
Symptoms of Exposure: Eye discomfort, skin irritation, mild respiratory irritation, gastrointestinal disturbance if swallowed in excess
Sensitization: Not a known sensitizer under normal conditions
Other Health Effects: Research on estrogenic activity ongoing, some animal studies indicate endocrinological effects at high doses
Ecotoxicity: Not highly toxic to aquatic organisms based on current data, but releases to the environment should be minimized
Persistence and Degradability: Genistein breaks down gradually under natural conditions, not readily biodegradable
Bioaccumulation Potential: Does not bioaccumulate significantly in aquatic or terrestrial organisms
Mobility in Soil: Low--moderate mobility, likely to adsorb onto soil and sediment
Other Adverse Effects: No known major environmental hazards with responsible handling and disposal
Waste Treatment Methods: Dispose of contents and container according to local, state, and federal regulations for chemical waste
Disposal of Contaminated Packaging: Rinse and neutralize, then manage as chemical waste
Additional Information: Do not release into drains, soil, or watercourses; incinerate or landfill using authorized service in compliance with environmental guidelines
UN Number: Not regulated as a hazardous material for transport
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Transport Precautions: Protect containers from physical damage and moisture, ensure packaging is secure and labeled while in transit
Safety, Health and Environmental Regulations: Not listed as a controlled substance, check local requirements for workplace exposure, hazard communication, and waste management
TSCA Status (US): Listed on the Toxic Substances Control Act Inventory
REACH Status (EU): Registered under REACH
Other World Inventories: Present on Australia AICS, Canada DSL, Japan ENCS, China IECSC
Labeling Requirements: Follows Globally Harmonized System (GHS) labeling with warning symbols and safety data included
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
