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Product Name: Fenbendazole
Chemical Name: Methyl 5-(phenylthio)-2-benzimidazolecarbamate
CAS Number: 43210-67-9
Recommended Use: Antiparasitic agent for veterinary purposes
Synonyms: Panacur, Safe-Guard, Fendazole
Manufacturer: Listed by the supplier or producer
Emergency Contact: Provided on the label or by the manufacturer
Address: As per packaging or supplier details
Telephone: Given on the official MSDS document
Classification: Not classified as hazardous according to GHS criteria for the majority of handling conditions
Signal Word: No specific signal word under typical exposure scenarios
Hazard Statements: May cause mild skin or eye irritation; Prolonged contact or inhalation of dust might result in respiratory discomfort
Precautionary Statements: Avoid breathing dust; Wear personal protection such as gloves; Wash thoroughly after handling; Avoid direct eye contact
Potential Health Effects: Inhalation can cause minor respiratory irritation; Eye contact may result in mild discomfort; Ingestion of large amounts could lead to abdominal pain or nausea; Skin exposure rarely causes noticeable irritation but should be avoided
Environmental Impact: Toxic to aquatic organisms if released in large quantities
Chemical Formula: C15H13N3O2S
Purity: Typically 97%-99% active ingredient in technical grade
Major Components: Fenbendazole (active compound)
Minor Components: Trace impurities from synthesis (listed where applicable by supplier)
Additives: None in pure substance, possible diluents or carriers in product formulations
Inhalation: Remove person to fresh air; Seek medical attention if symptoms persist or worsen
Skin Contact: Wash thoroughly with soap and water; Remove contaminated clothing
Eye Contact: Rinse cautiously with water for 15 minutes; Remove contact lenses if present; Get medical attention if irritation develops
Ingestion: Rinse mouth with water; Do not induce vomiting unless directed by a medical professional; Obtain medical advice for large or accidental ingestion
Most Important Symptoms: Mild respiratory tract irritation, temporary eye discomfort, possible skin dryness
Suitable Extinguishing Media: Dry chemical powder, foam, carbon dioxide, water spray
Unsuitable Extinguishing Media: Not identified
Special Hazards: Thermal decomposition can release CO, CO2, nitrogen oxides, and sulfur oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Specific Methods: Use water spray to cool unopened containers; Prevent fire-fighting effluent from entering drains or waterways
Combustion Products: Irritating or toxic fumes may be generated in fire
Personal Precautions: Avoid generating dust; Use personal protective equipment like gloves and goggles; Remove unprotected people from area
Environmental Precautions: Avoid release into drains, surface water, and soil; Report significant spills to environmental authorities as required
Clean-Up Methods: Collect spilled material using non-sparking tools and transfer to suitable container for disposal; Vacuum or sweep up avoiding raising dust; Wash area with suitable detergent and water to prevent residue accumulation
Handling: Handle in well-ventilated area; Minimize dust generation; Wear protective equipment including gloves and safety glasses or goggles; Wash hands before eating, drinking, or smoking after use
Storage: Store tightly closed in original container; Keep in a dry, cool, well-ventilated place away from incompatible materials like strong acids or oxidizing agents; Limit exposure to light, humidity, and temperature extremes; Restrict access to authorized personnel for bulk quantities
Engineering Controls: Local exhaust ventilation to minimize dust; Work in controlled area with proper containment
Personal Protective Equipment: Protective gloves (chemical-resistant), lab coat or work clothes, safety glasses with side shields
Respiratory Protection: Dust mask or appropriate respirator when excessive dust is generated
Hygiene Measures: Wash hands and arms thoroughly after handling; Do not eat, drink, or smoke in work areas
Occupational Exposure Limits: Not established specifically for Fenbendazole; Use general dust limits for nuisance dust as a guideline
Appearance: White to off-white crystalline powder
Odor: Odorless or very faint odor
Odor Threshold: Not applicable
pH: Not applicable in solid state
Melting Point/Range: 233-234°C
Boiling Point: Decomposes before boiling
Flash Point: Not flammable under typical conditions
Evaporation Rate: Not volatile
Flammability: Not easily ignitable
Vapor Pressure: Negligible at ambient temperature
Vapor Density: Not available
Relative Density: About 1.5 g/cm³
Solubility: Poorly soluble in water; Soluble in dimethyl sulfoxide (DMSO), slightly soluble in acetone and ethanol
Partition Coefficient (n-octanol/water): Log P value approximately 2.44
Auto-ignition Temperature: Not determined
Decomposition Temperature: >200°C
Viscosity: Not applicable to solid
Particle Size: Varies by manufacturer and application
Chemical Stability: Stable under normal temperatures and recommended conditions of storage
Reactivity: Does not react vigorously with water, acids, or bases
Conditions to Avoid: High humidity, temperature extremes, open flames, sources of ignition
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur compounds on decomposition or combustion
Polymerization: Not known to occur
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg; Low acute toxicity profile in mammals
Skin Corrosion/Irritation: Mild and reversible skin irritation may occur on prolonged exposure
Serious Eye Damage/Irritation: May cause mild eye irritation
Respiratory Sensitization: Not classified as a respiratory sensitizer
Skin Sensitization: Not a known skin sensitizer in standard tests
Chronic Toxicity: No significant effects reported at anticipated exposure levels; Long-term, high-dose animal testing revealed occasional liver and blood changes
Carcinogenicity: Not listed as a carcinogen by IARC, ACGIH, NTP, or OSHA
Mutagenicity: Laboratory studies have not found significant mutagenic potential
Reproductive Toxicity: No adverse reproductive or developmental effects seen in animal studies at typical veterinary doses
Other Effects: High doses possibly cause mild gastrointestinal disturbance, temporary changes in liver enzymes, weight loss in animals
Aquatic Toxicity: Toxic to certain aquatic organisms with potential to cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Resistant to rapid degradation; May persist in soil and water for extended periods
Bioaccumulation Potential: Potential for moderate bioaccumulation in aquatic species based on partition coefficient
Mobility in Soil: Low water solubility reduces mobility; Most remains bound to soil particles
Ecotoxicological Data: LC50 (rainbow trout): approximately 3.2 mg/L (96h); EC50 (Daphnia magna): approximately 6.2 mg/L (48h)
Other Environmental Effects: Not expected to damage ozone layer or contribute to photochemical smog
Disposal Methods: Follow local, regional, or national regulations for pharmaceutical waste disposal; Incinerate in approved facility or dispose of in authorized landfill
Packaging Disposal: Render packaging unusable and dispose of according to regional waste management rules; Avoid reuse of empty containers
Precautions: Do not discharge into sewers, rivers, or water bodies; Contact waste handler for complete destruction in a manner compliant with environmental laws
UN Number: Not regulated as a dangerous good for transport under most international regulations (ADR, IMDG, IATA)
Proper Shipping Name: Not applicable; Name by substance (Fenbendazole)
Transport Hazard Class: None assigned
Packing Group: Not applicable
Special precautions: Ensure packaging is intact and secure; Prevent damage and loss of labels
Environmental Hazards: Not a marine pollutant under current IMDG code but take care to prevent spills near water sources
Regulatory Status: Fenbendazole is an approved veterinary antiparasitic; Regulations vary by country and region
GHS Labeling: No signal word or pictograms for standard handling; Consult local or product-specific data for requirements
Inventory Status: Listed on chemical inventories in most major regions (e.g., TSCA in the US, DSL in Canada, EINECS in EU)
Specific Restrictions: Veterinary use only unless otherwise permitted; Not licensed for human consumption in most countries
SARA Title III (US): Not listed under Section 313
California Proposition 65: Not listed
Other Regulation: Consult national and local regulations for exposure limits, environmental discharge, and occupational safety requirements
