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Material Safety Data Sheet (MSDS) – Eucalyptol

Identification

Product Name: Eucalyptol
Synonyms: 1,8-Cineole; Cajeputol
Chemical Formula: C10H18O
Molecular Weight: 154.25 g/mol
CAS Number: 470-82-6
Uses: Solvent, Fragrance, Flavoring, Pharmaceutical applications

Hazard Identification

Classification: Flammable liquid (Category 3), Acute oral toxicity (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, Harmful if swallowed, Causes skin irritation, Causes serious eye irritation
Pictograms: Flame, Exclamation mark
Routes of Exposure: Inhalation, ingestion, eye and skin contact
Precautionary Statements: Keep away from heat, sparks, open flames. Wear protective gloves and eye protection. Wash hands thoroughly after handling. Avoid breathing vapors.

Composition / Information on Ingredients

Chemical Name: Eucalyptol
Concentration: ≥ 99%
Impurities: Trace amounts of other terpene compounds
Component Type: Pure substance
Hazardous Components: Eucalyptol (Cineole)

First Aid Measures

Inhalation: Remove person to fresh air, keep comfortable for breathing. Seek medical attention if symptoms develop.
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water. Seek medical attention if irritation persists.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing. Obtain medical attention if irritation continues.
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical advice. If symptoms like nausea, dizziness, or respiratory issues occur, transport victim to a healthcare facility.
Most Important Symptoms and Effects: Eye and skin irritation, headache, nausea, drowsiness

Fire-Fighting Measures

Suitable Extinguishing Media: Alcohol-resistant foam, carbon dioxide, dry chemical powder
Unsuitable Media: Water jet
Specific Hazards: Vapors may travel long distances and flash back. Hazardous decomposition products may include carbon monoxide, carbon dioxide, other irritant gases.
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Special Procedures: Cool containers exposed to fire with water spray. Remove containers where possible if safe to do so.

Accidental Release Measures

Personal Precautions: Avoid inhalation of vapors, ensure adequate ventilation, remove all sources of ignition. Wear gloves, protective clothing, and safety goggles.
Environmental Precautions: Prevent entry into drains, sewers, or watercourses.
Methods for Cleaning Up: Absorb spill with inert material such as sand or earth. Collect and dispose of according to local regulations. Wash the spill area thoroughly with water after material pickup is complete.

Handling and Storage

Safe Handling: Handle in well-ventilated areas, keep away from heat and open flame, avoid inhaling vapors or mist. Use spark-proof tools and explosion-proof equipment.
Storage: Keep in tightly closed original container, stored in a cool, dry, and well-ventilated place away from incompatible substances such as oxidizing agents. Keep out of direct sunlight and segregate from food and drink.

Exposure Controls and Personal Protection

Exposure Limits: No OSHA or ACGIH exposure limit established. Recommend limiting exposure through engineering controls.
Engineering Controls: Use local exhaust or general dilution ventilation to keep vapor concentrations below exposure limits.
Personal Protective Equipment: Splash-resistant goggles, chemical-resistant gloves, protective clothing. Use respiratory protection if vapor concentration exceeds acceptable levels.
Hygiene Measures: Wash hands, face, and exposed skin after handling. Do not eat, drink, or smoke during use.

Physical and Chemical Properties

Appearance: Colorless liquid
Odor: Characteristic, camphor-like odor
Odor Threshold: Not determined
pH: Not applicable
Melting Point: 1–2°C
Boiling Point: 176–177°C
Flash Point: 49°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid
Vapor Pressure: 2.4 mm Hg at 25°C
Vapor Density: 5.3 (Air=1)
Solubility: Slightly soluble in water, soluble in ethanol and most organic solvents
Partition Coefficient: log Kow 2.82
Auto-ignition Temperature: 255°C
Decomposition Temperature: Not determined
Viscosity: Not determined

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions.
Conditions to Avoid: Exposure to heat, open flames, sparks, and incompatible materials.
Incompatible Materials: Strong oxidizers, acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, various hydrocarbons.
Hazardous Polymerization: Will not occur under recommended handling conditions.

Toxicological Information

Acute Toxicity: Oral LD50 (rat): approx. 2480 mg/kg; Dermal LD50 (rabbit): not well established
Skin Corrosion/Irritation: Causes irritation
Serious Eye Damage/Eye Irritation: Causes eye irritation
Respiratory Sensitization: Can irritate mucous membranes if inhaled
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: Not expected to cause genetic defects
Reproductive Toxicity: Data not sufficient for classification
Chronic Effects: Prolonged exposure may cause headache, dizziness, or nausea
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion

Ecological Information

Toxicity: Harmful to aquatic life with long lasting effects. Expected LC50 values (fish): 50–60 mg/L/96h
Persistence and Degradability: Readily biodegradable under aerobic conditions
Bioaccumulation Potential: Bioconcentration factor (BCF) estimated to be low
Mobility in Soil: Moderately mobile in soil, may volatilize from water surfaces
Other Adverse Effects: Prevent large spills from entering waterways to reduce potential environmental impact

Disposal Considerations

Waste Disposal Methods: Dispose of contents/container in accordance with local/regional/national/international regulations. Incinerate under controlled conditions or use approved chemical waste disposal firm.
Contaminated Packaging: Rinse thoroughly and dispose or recycle as required by local guidelines.
Additional Information: Do not dispose to drains, surface water, or ground water.

Transport Information

UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (Eucalyptol)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Environmental Hazards: Not classified as marine pollutant
Transport Labels Required: Flammable liquid
Special Precautions: Store and transport in accordance with applicable laws and avoid package rupture during transit

Regulatory Information

TSCA Inventory: Listed
REACH Registration: Registered substance in EU
OSHA: Hazardous chemical, covered under OSHA HazCom Standard
SARA Title III: Not extremely hazardous, not under Section 313 reporting
California Prop 65: Not listed
WHMIS Classification (Canada): B2 (Flammable liquid), D2B (Toxic material causing other toxic effects)
Other International Regulations: Compliant with applicable hazard communication standards in Australia, Japan, China; further review for region-specific requirements recommended