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Material Safety Data Sheet (MSDS): Ethylenediaminetetraacetic Acid Disodium Salt

Identification

Chemical Name: Ethylenediaminetetraacetic Acid Disodium Salt Dihydrate
Common Names: Disodium EDTA, Disodium ethylenediaminetetraacetate
Synonyms: Disodium EDTA, Edetic acid disodium salt
CAS Number: 6381-92-6
Recommended Use: Chelating agent in laboratories, water treatment, pharmaceuticals
Supplier/Manufacturer: Identified on package or supplier documentation, contact information typically provided
Emergency Contact: Refer to supplier emergency telephone and address details supplied with product

Hazard Identification

GHS Classification: Eye irritation, Category 2A; Acute toxicity, oral, Category 4; Skin irritation, Category 2
Label Elements: Signal word “Warning”, GHS pictograms for exclamation mark
Hazard Statements: Causes serious eye irritation. Harmful if swallowed. Causes skin irritation.
Precautionary Statements: Avoid contact with eyes, skin, and clothing. Wear protective gloves and eye protection. Avoid ingesting material. Do not breathe dust.
Other Hazards: May cause mild respiratory irritation with prolonged exposure to airborne dust. Dust may form explosive mixtures in air under certain conditions.

Composition / Information on Ingredients

Chemical Name: Ethylenediaminetetraacetic Acid Disodium Salt Dihydrate
Concentration: Over 98% by weight
CAS Number: 6381-92-6
Impurities and Stabilizing Additives: Less than 2% water, minimal trace impurities

First Aid Measures

General Advice: Move away from exposure area to fresh air or safe environment. Immediately remove contaminated clothing.
Inhalation: Move person to fresh air. Seek medical attention for symptoms like shortness of breath or coughing.
Skin Contact: Wash thoroughly with soap and plenty of water. Remove contaminated clothes and shoes. Get medical attention if irritation continues.
Eye Contact: Rinse cautiously with water for at least 15 minutes. Remove contact lenses. Do not rub eyes. Seek medical advice.
Ingestion: Rinse mouth with water without inducing vomiting unless instructed by medical personnel. Seek medical assessment for nausea or discomfort.
Most Important Symptoms and Effects, Both Acute and Delayed: Eye, skin, and respiratory tract irritation; nausea after ingestion; potential for delayed allergic reaction in sensitive individuals.
Notes to Physician: Treat symptomatically and supportively.

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide. Avoid high-pressure jet streams that may spread dust.
Special Hazards Arising from Chemical: Emits toxic fumes of nitrogen oxides (NOx), carbon monoxide, and carbon dioxide when heated above decomposition.
Advice for Firefighters: Wear self-contained breathing apparatus and full protective gear. Stay upwind and keep unwanted personnel from the area.
Fire and Explosion Hazards: Powdered or granular material may form combustible dust clouds in air under particular conditions, posing explosion risk. Take precautions to minimize dust generation.

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, and dust mask. Prevent further release and avoid breathing dust.
Environmental Precautions: Keep out of drains, water courses, and soil. Prevent entry into sewers and natural waterways.
Cleanup Methods: Sweep up gently to minimize dust, collect in closed containers for disposal. Wash spill site with soap and water after material pickup.
Other Recommendations: Ensure adequate ventilation during cleanup. Dispose of all cleanup materials in accordance with local and national regulations.

Handling and Storage

Handling: Work in well-ventilated area. Avoid creating dust. Use proper personal protective equipment including gloves and protective eyewear. Prevent contact with skin and eyes.
Storage: Store in tightly closed containers away from moisture, heat, and incompatible materials such as strong acids, oxidizers, and foodstuffs. Keep in a dry, cool, well-ventilated area, and segregate from edible materials.
Specific Storage Requirements: Label container clearly. Check regularly for leaks or damage. Place material away from sources of ignition and direct sunlight.

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limits for this compound from OSHA or ACGIH, but control dust as for nuisance particulates.
Engineering Controls: Use local exhaust ventilation or process enclosure to minimize airborne exposure. Implement dust control measures.
Personal Protective Equipment: Chemical-resistant gloves, goggles, lab coat, and dust mask or respirator (NIOSH-approved) for dusty operations.
Hygiene Measures: Wash hands thoroughly after handling the chemical, before eating, drinking, or using restrooms. Keep work clothes separate from regular garments. Shower after extended exposure.
Environmental Controls: Prevent release to the environment. Ensure procedures for decontamination and waste handling are enforced.

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Odorless
pH (5% solution): Around 4 to 6
Melting Point: Decomposes above 240°C
Boiling Point: Not applicable (decomposes)
Flash Point: Not applicable (non-flammable solid)
Solubility in Water: Freely soluble
Vapor Pressure: Negligible
Relative Density: Around 1.6 g/cm³
Partition Coefficient (n-octanol/water): Not available
Evaporation Rate: Not applicable for solid
Explosive Properties: Dust can present explosion hazard if dispersed in air and ignited
Oxidizing Properties: Non-oxidizing

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions. Degrades slowly with prolonged exposure to moisture.
Reactivity: Reacts with strong acids, releasing toxic gases.
Possibility of Hazardous Reactions: Dust may form explosive atmospheres in confined spaces.
Conditions to Avoid: Elevated temperatures, contact with acids or strong oxidizing agents, exposure to moisture.
Incompatible Materials: Strong acids, strong oxidizers, reducing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, disodium salts.

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin contact, eye contact.
Acute Toxicity: Oral LD50 (rat): Around 2000 mg/kg; inhalation and dermal toxicity data limited, generally low toxicity.
Skin Irritation: Causes moderate irritation, may cause redness or inflammation with sustained contact.
Eye Irritation: Strongly irritating; exposure can lead to watering, redness, blurred vision.
Chronic Effects: Prolonged or repeated exposure may cause dermatitis or allergic reactions.
Sensitization: Not considered a sensitizer for most people, but individuals with allergies may show heightened symptoms.
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA.
Mutagenicity and Teratogenicity: No strong evidence from existing data.
Other Health Effects: Ingestion of large amounts can lead to disturbances in electrolyte balance, especially if pre-existing kidney issues exist.

Ecological Information

Aquatic Toxicity: Moderate toxicity to aquatic organisms. LC50 (Daphnia magna, 48hr): 610 mg/L. Long-term harm possible due to chelation of metal ions, which affects aquatic plants and shell growth.
Persistence and Degradability: Moderately persistent in soil and water. Degrades slowly by microbial action.
Bioaccumulation Potential: Low potential, not likely to concentrate in organisms.
Mobility in Soil: High mobility; soluble in water, leaches through soil rapidly.
Other Adverse Effects: May increase transport of toxic metals in water bodies by chelation, leading to unintended environmental exposure.

Disposal Considerations

Waste Treatment Methods: Collect and place in approved chemical waste containers. Dispose of by incineration or landfill at licensed facility, following federal, state, and local requirements.
Contaminated Packaging: Rinse containers before recycling or proper disposal. Do not reuse empties for food storage.
Disposal Precautions: Do not allow material to reach sewage system. Wear protective equipment during waste handling.

Transport Information

UN Number: Not classified as hazardous for transport globally; check local regulations.
Proper Shipping Name: Not regulated as a dangerous good.
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not classified as marine pollutant, but indirect impacts possible.
Special Precautions: Avoid generating dust during transport. Keep away from acids and foodstuffs.
Transport in Bulk: Observe industry-specific handling practices to minimize environmental and worker exposure.

Regulatory Information

OSHA Status: Generally not specifically regulated; comply with general safety standards.
TSCA (Toxic Substances Control Act): Listed
EINECS/ELINCS: Listed
SARA Title III (Sections 311/312): Immediate health hazard
SARA Title III (Section 313) and CERCLA: Not subject to reporting
WHMIS Classification: Eye and skin irritant
California Proposition 65: Not on list
Other Regulations: Check local and state laws regarding environmental discharge, use, and disposal.
Product Label Requirements: Keep out of reach of children. Read label before use. Wear specified protective equipment.