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Material Safety Data Sheet: Ethyl Arachidonate

Identification

Product Name: Ethyl Arachidonate
Chemical Formula: C24H40O2
Synonyms: Arachidonic acid ethyl ester, Ethyl 5,8,11,14-eicosatetraenoate
CAS Number: 52449-79-7
Manufacturer Information: Name, address, and contact details of supplier or manufacturer, including phone number for emergencies.
Recommended Use: Laboratory research, synthesis of biologically active molecules.
Restrictions: Non-food, non-cosmetic use only.
Emergency Phone: Emergency contact number for chemical spills or exposures.

Hazard Identification

Classification: Eye irritant, skin irritant; may cause mild respiratory issues if inhaled in vapor or fine mist form.
GHS Signal Word: Warning
Hazard Statements: Causes mild skin and eye irritation; may cause respiratory discomfort upon inhalation.
Precautionary Statements: Wear personal protective equipment, avoid breathing vapors, wash hands thoroughly after handling.
Routes of Exposure: Skin, eyes, inhalation.
Symptoms: Redness, itching, coughing, headache.
Label Elements: Standard pictograms for irritant, exclamation mark.
Aggravating Conditions: Those with respiratory conditions or skin sensitivities should avoid unnecessary exposure.

Composition / Information on Ingredients

Chemical Name: Ethyl Arachidonate
Common Name: Arachidonic acid ethyl ester
PURITY: ≥98%
CAS Number: 52449-79-7
EC Number: 257-968-7
Impurities: Trace amounts of solvent residues (commonly ethanol) and minor fatty acid esters.
Other Components: None intended or hazardous.

First Aid Measures

General: Move exposed person to fresh air, remove contaminated clothing.
Skin Contact: Wash exposed area with soap and water for at least fifteen minutes, seek medical advice if irritation develops.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek medical attention if symptoms persist.
Inhalation: Move to fresh air, monitor for respiratory distress, seek medical help if symptoms continue.
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical attention if feeling unwell.
Advice for Medical Personnel: Provide symptomatic treatment and supportive care as indicated by the patient’s condition.

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam.
Unsuitable Extinguishing Media: High-pressure water jets can spread the material.
Specific Hazards: Burns with generation of carbon oxides and irritating fumes; dense smoke may occur.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, chemical-resistant clothing.
Firefighting Procedures: Evacuate personnel from the area, cool containers with water spray to avoid rupture, control runoff to prevent environmental contamination.
Thermal Decomposition Products: Carbon monoxide, carbon dioxide, possibly small amounts of hazardous organic compounds.

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, and lab coat; avoid inhaling vapors, ensure adequate ventilation.
Spill Cleanup Procedures: Absorb spill with inert material (sand, vermiculite), transfer to a proper waste container, avoid contact with skin and eyes.
Environmental Precautions: Prevent entry into drains, surface water, or soil; notify relevant authorities if large spills threaten the environment.
Methods for Containment: Stop the source of the spill, contain liquid, use nonsparking tools for handling.
Decontamination: Wash spill site after material pickup is complete.

Handling and Storage

Handling: Use only in well-ventilated areas, avoid contact with eyes, skin; wear proper protective equipment.
Storage Conditions: Keep tightly closed in a cool, dry, and well-ventilated place, protected from light and moisture.
Incompatibilities: Strong oxidizers, acids, and bases.
Hygiene Practices: Wash hands and face before eating, drinking, and after work.
Safe Transfer: Use grounded and bonded containers for large scale transfers, avoid inhaling fumes.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for this compound; follow good industrial hygiene practices.
Engineering Controls: Use fume hood or local exhaust.
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), safety glasses with side shields, lab coat or apron.
Respiratory Protection: Use NIOSH/MSHA-approved respirator if vapor or mist exposure likely.
Environmental Exposure: Prevent release to environment, use spill control equipment and practices.

Physical and Chemical Properties

Physical State: Oily liquid
Color: Pale yellow to amber
Odor: Faint, fatty odor
Melting Point: -22°C
Boiling Point: Approx. 435°C
Flash Point: 252°C (estimated, closed cup)
Solubility: Insoluble in water, soluble in ethanol, diethyl ether, other organic solvents
Vapor Pressure: Very low at room temperature
Specific Gravity: 0.93–0.95
Viscosity: Medium
pH: Not applicable (non-aqueous)

Stability and Reactivity

Chemical Stability: Stable under recommended storage, sensitive to air and light over long term.
Potential Danger: Can react with oxidizing agents to create risk of fire.
Conditions to Avoid: Exposure to heat, flames, and strong light; contacting incompatible materials.
Hazardous Decomposition: Carbon oxides, possibly small quantities of toxic volatile compounds.
Polymerization: No risk expected under normal conditions.

Toxicological Information

Likely Routes of Exposure: Inhalation, dermal, ocular contact, oral.
Acute Toxicity: No acute toxicity data available; based on structure, large doses may cause mild gastrointestinal distress.
Skin Corrosion/Irritation: Mild skin irritation possible after prolonged contact.
Serious Eye Damage/Irritation: May cause redness, watering, temporary discomfort.
Respiratory Irritation: Vapors or fine mists could cause temporary coughing or sore throat.
Chronic Effects: No data indicating long-term effects; chronic exposure not recommended.
Carcinogenicity: No components listed as carcinogenic.
Reproductive Toxicity: No available data.
Symptoms Noted: Red eyes, skin redness, mild respiratory irritation.

Ecological Information

Ecotoxicity: Not expected to be acutely toxic, but large quantities could harm aquatic organisms due to oil films on water surfaces.
Persistence and Degradability: Biodegradable over time in the environment.
Bioaccumulation Potential: Low likelihood due to fatty acid structure.
Mobility in Soil: Low mobility, likely to remain near point of release in soils.
Other Adverse Effects: May cause temporary film on surface waters, reducing oxygen exchange.
Precaution: Prevent large releases from entering drainage or watercourses.

Disposal Considerations

Waste Disposal Methods: Collect material in properly labeled containers, dispose of at approved chemical waste facility.
Contaminated Packaging: Dispose of as hazardous waste, triple rinse containers before disposal.
Handling Procedures: Wear protective equipment, avoid generating dusty conditions, follow local regulations.
Special Handling: Do not flush to drain, do not incinerate waste in open air.
Legal Disposal: Follow municipal, state, or federal regulations regarding disposal of chemical and packaging.

Transport Information

UN Number: None assigned
Proper Shipping Name: Not regulated for ground, air, or sea transport as a dangerous good.
Transport Hazard Class: None
Packing Group: None
Special Precautions: Protect containers from physical damage, keep away from food and feedstuffs.
Transport Label: Basic labeling required indicating chemical identity and hazard warning.
Bulk Transportation: Avoid direct sunlight, provide secondary containment where appropriate.

Regulatory Information

US TSCA Inventory: Listed
REACH Registration: May require registration for large-scale use in the EU.
Canada DSL/NDSL: Listed/non-listed status should be checked.
Federal Regulations: No specific OSHA or EPA restrictions listed.
State Regulations: Check individual states for applicable chemical safety regulations.
WHMIS Classification: Not controlled.
SARA/Title III: Not regulated.
Labeling Requirements: Appropriate hazard warnings, product identification, manufacturer/supplier name and address.