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Material Safety Data Sheet (MSDS) for Ethoxyquinoline

Identification

Product Name: Ethoxyquinoline
Chemical Family: Quinoline derivatives
Synonyms: 2-Ethoxyquinoline, Quinoline, 2-ethoxy-
Recommended Use: Laboratory chemicals, research and development
Supplier Details: [Company Name], [Address], [Contact Number], [Email for emergency]
Emergency Phone Number: [Local Emergency Number or CHEMTREC]

Hazard Identification

Classification: Flammable liquid (Category 3), Acute toxicity oral and dermal (Category 4), Skin and eye irritation (Category 2)
Signal Word: Warning
GHS Pictograms: Flame, Exclamation Mark
Hazard Statements: May cause irritation to the skin, eyes, and respiratory system. Harmful if swallowed. Flammable liquid and vapor. May be harmful in contact with skin. Prolonged exposure can affect the central nervous system.
Precautionary Statements: Avoid breathing mist or vapor, use only in well-ventilated areas, keep away from heat/sparks/open flames/hot surfaces, keep container tightly closed, wear protective gloves and eye protection.

Composition / Information on Ingredients

Chemical Name: Ethoxyquinoline
Common Name: 2-Ethoxyquinoline
CAS Number: [Insert CAS Number]
Concentration: ≥ 98%
Impurities: May contain minor trace solvents or byproducts not exceeding 2%.

First Aid Measures

Inhalation: Move person to fresh air. Seek medical attention if breathing difficulties develop or persist. Provide oxygen if available and symptoms are severe.
Skin Contact: Remove contaminated clothing immediately. Wash skin thoroughly with soap and water. Get medical aid if irritation persists.
Eye Contact: Rinse eyes cautiously with water for at least 15 minutes. Remove contact lenses if easy to do. Continue rinsing and call a physician.
Ingestion: Do not induce vomiting. Rinse mouth with water. Never give anything by mouth to an unconscious person. Seek immediate medical help.
Symptoms: Irritation, redness, coughing, headache, dizziness. In severe cases, respiratory distress or drowsiness may occur.

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam. Use water spray to cool fire-exposed containers.
Unsuitable Media: Direct stream of water may spread fire.
Hazardous Combustion Products: Oxides of nitrogen, carbon monoxide, carbon dioxide, toxic fumes.
Protective Equipment: Self-contained breathing apparatus and full protective gear. Approach upwind and avoid inhalation of vapors.
Other Information: Vapors can travel to a source of ignition and flash back. Containers exposed to fire may explode.

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate enclosed spaces, remove ignition sources, wear protective clothing and respirator.
Environmental Precautions: Prevent entry into drains, water courses or soil. Notify local authorities in case of major spillage.
Methods for Clean-Up: Absorb with inert material like sand or earth. Place in suitable containers for disposal. Wash spill site after material pickup.
Disposal: Follow all federal, state, and local disposal regulations for hazardous chemicals.

Handling and Storage

Handling: Avoid contact with skin, eyes, and clothing. Do not breathe mist, vapor, or spray. Use only in a chemical fume hood or well-ventilated place. Keep away from sources of ignition. No eating, drinking, or smoking in work area.
Storage: Keep containers tightly closed in a cool, dry, well-ventilated location away from direct sunlight, incompatible products like oxidizers and strong acids. Store away from heat or sparks. Use corrosion-resistant shelves and ensure secondary containment where possible.

Exposure Controls and Personal Protection

Exposure Limits: No established OSHA/ACGIH limits for Ethoxyquinoline; minimize exposure as much as possible.
Engineering Controls: Use mechanical exhaust or local ventilation to avoid vapor build-up. Install eye-wash stations and safety showers in work areas.
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles, chemical splash shield, flame-resistant lab coat, suitable respiratory protection if ventilation is inadequate.
Hygiene Measures: Wash hands thoroughly after handling. Remove contaminated clothing and wash before reuse.

Physical and Chemical Properties

Appearance: Pale yellow liquid or crystalline solid (check batch/lot description)
Odor: Mild aromatic
Odor Threshold: Not determined
pH: Not applicable (non-water soluble)
Melting Point/Freezing Point: 34 - 39 °C (may vary slightly by manufacturer)
Boiling Point: 280 – 290 °C
Flash Point: ~110 °C (closed cup)
Evaporation Rate: Slow
Flammability: Flammable liquid
Vapor Pressure: Low at room temperature
Vapor Density: Heavier than air
Solubility in Water: Poorly soluble
Partition Coefficient (log Kow): Estimated >2
Auto-ignition Temperature: Not determined
Decomposition Temperature: No data available
Viscosity: Not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, decomposes on prolonged exposure to light or air.
Reactivity: May react with strong oxidizing agents, acids, and alkalis.
Hazardous Reactions: Releases toxic vapors during decomposition or combustion.
Polymerization: Hazards not anticipated under normal handling and storage.
Conditions to Avoid: Heat, sparks, open flames, direct sunlight, humidity, and contact with incompatible materials.
Incompatible Materials: Strong acids, strong bases, oxidizers.

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion.
Acute Toxicity: Based on animal data, LD50 (oral, rat) ranges between 300–2000 mg/kg; skin absorption may cause mild to moderate irritation.
Skin Corrosion/Irritation: Causes moderate irritation; prolonged/repeated contact may dry skin.
Serious Eye Damage/Irritation: Causes irritation, redness, watering.
Respiratory Sensitization: No data found for respiratory allergies.
Carcinogenicity: Not listed in IARC, NTP, OSHA.
Reproductive Toxicity: No published evidence of reproductive risks, caution due to chemical structure.
Specific Target Organ Toxicity: High doses can cause central nervous system effects: headache, dizziness, drowsiness.
Symptom Description: Nausea, dry mouth, sore throat, abdominal pain on ingestion.

Ecological Information

Toxicity to Aquatic Life: Harmful to aquatic organisms, potential for acute and long-term adverse effects in aquatic environments.
Biodegradability: Not readily biodegradable, persists under typical environmental conditions.
Bioaccumulative Potential: High potential due to estimated log Kow > 2; likely to accumulate in aquatic organisms.
Mobility in Soil: Low mobility due to low water solubility and high partition coefficient.
Other Adverse Effects: Avoid uncontrolled release into the environment, report major discharges to environmental authorities.

Disposal Considerations

Waste Treatment Methods: Treat as hazardous chemical waste. Collect and store in closed, labeled containers. Use incineration in approved facility with afterburner and scrubber. Follow all national, state, and local regulations for hazardous waste disposal.
Contaminated Packaging: Dispose of containers as hazardous waste. Ensure thorough triple-rinsing, puncture to prevent reuse, properly label before final disposal.
Special Precautions: Do not discharge into drains, surface water, or soil.

Transport Information

UN Number: [Insert UN Number as per latest regulations]
UN Proper Shipping Name: Flammable liquid, n.o.s. (Ethoxyquinoline)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Environmental Hazards: Marine pollutant
Transport Labels: Flammable liquid symbol
Special Precautions: Keep containers upright and tightly sealed. Maintain packaging integrity. Transport only in permitted containers with safety documentation.

Regulatory Information

US Federal Regulations: Subject to TSCA Inventory. Not listed under SARA Title III Sections 302/304, 313. No OSHA PEL or ACGIH TLV established.
EU Regulations: Classified under CLP/GHS as flammable, harmful if swallowed, irritating to eyes and skin.
International Inventory: Notify local authorities prior to significant usage or transportation. Registered in select countries under chemical safety boards.
Other Regulations: Always check local, state, and regional government requirements before handling or disposal. Workers must receive training on chemical hazards, safe handling, and emergency procedures.