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Product Name: Epimedium Extract
Synonyms: Horny Goat Weed Extract, Herba Epimedii Extract
Chemical Family: Plant Extract
Recommended Uses: Herbal supplements, nutraceuticals, traditional medicine
Supplier Details: Manufacturer information, emergency contact number, address, email for further safety support
CAS Number: 489-32-7 (primary constituent icariin)
Formula: Mixture (main active: Icariin)
Emergency Overview: Pale yellow to brown powder, herbal odor
Hazard Class: Not classified as hazardous under OSHA 29 CFR 1910.1200
Signal Word: None
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Potential Health Effects: Irritation to eyes, skin, and respiratory tract. May cause discomfort if inhaled or ingested in large amounts. Limited toxicological data available
GHS Label Elements: None required
Precautionary Statements: Avoid breathing dust. Avoid contact with skin and eyes. Wash hands thoroughly after handling
Main Component: Epimedium Extract (90–95%)
Active Constituent: Icariin (5–60%), percentage varies by manufacturer
Other Ingredients: Plant polysaccharides, flavonol glycosides, trace alkaloids, moisture (<5%)
Impurities: Trace solvents from extraction, not expected at hazardous levels
Ingredient Source: Dried aerial parts of Epimedium brevicornum or related species
Allergens: None listed, but users with sensitivity to herbal products should take caution
Inhalation: Move person to fresh air. Keep at rest and monitor breathing. Seek medical attention for persistent irritation
Skin Contact: Remove contaminated clothing. Wash with plenty of soap and water. Contact healthcare provider if redness or discomfort remains
Eye Contact: Immediately flush with water for at least 15 minutes, lifting eyelids occasionally. Seek medical attention if symptoms continue
Ingestion: Rinse mouth with water. Drink several glasses of water. Do not induce vomiting unless instructed by healthcare professional. Contact poison control or physician for large ingestions
Advice for Physician: Treat symptomatically. No specific antidote known
Suitable Extinguishing Media: Use water spray, dry chemical, CO2, or foam
Unsuitable Extinguishing Media: High-pressure water jets may spread powder
Special Hazards: Fine powder may form combustible dust mixtures with air. Burning produces CO, CO2, and irritating smoke
Protective Equipment for Firefighters: Wear full protective clothing and self-contained breathing apparatus
Advice: Cool fire-exposed containers with water spray. Avoid inhaling smoke and fumes. Prevent run-off from entering drains
Personal Precautions: Keep unprotected personnel away. Wear appropriate protective equipment (gloves, safety goggles, dust respirator)
Environmental Precautions: Prevent entry into sewers, surface, or groundwater
Methods for Clean-up: Avoid creating dust. Sweep or vacuum up material into suitable containers for disposal. Wash area with water after material pickup
Spill Reporting: Report large spills to proper authorities according to local requirements
Handling: Minimize dust generation. Use only with adequate ventilation. Wash hands after handling. Do not eat, drink, or smoke while working with the material
Storage: Store in tightly closed containers. Keep in a cool, dry, well-ventilated place, away from direct sunlight, heat sources, or moisture
Incompatibilities: Strong oxidizers, acids
Storage Temperature: 2–8°C preferred for stability over time
Safe Storage Labeling: Label containers with product name and hazard warnings
Engineering Controls: Use local exhaust ventilation or fume hood to minimize airborne dust
Personal Protective Equipment: Safety goggles, gloves resistant to chemicals, lab coat, dust mask or respirator (NIOSH-approved)
Hygiene Measures: Wash thoroughly after handling. Remove contaminated clothing and launder before reuse
Exposure Limits: Not established for Epimedium Extract. Use general nuisance dust limits (OSHA PEL: 15 mg/m³ for total dust; 5 mg/m³ respirable)
Environmental Controls: Keep material away from drains, soil, and open water to avoid environmental release
Appearance: Fine powder, pale yellow to brown
Odor: Light herbal or plant-like aroma
Odor Threshold: Not established
pH (1% solution): 4.0–7.0
Melting Point/Freezing Point: Decomposes on burning; no specific melting point
Boiling Point: Not applicable (solid, decomposes)
Flash Point: Not determined; dust explosion risk possible
Evaporation Rate: Not applicable
Flammability: Combustible as dust in air
Explosion Limits: Not determined
Vapor Pressure: Negligible at ambient temperatures
Vapor Density: Not applicable
Relative Density: 0.35–0.55 g/cm³ (bulk density)
Solubility: Partially soluble in water, soluble in ethanol
Partition Coefficient: Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 200°C (breakdown of components)
Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactions under normal use
Conditions to Avoid: Excessive heat, open flame, incompatible chemicals, moisture
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, irritating organic fumes
Polymerization: Not expected to occur
Acute Toxicity: No reliable acute LD50 data for extract. Individual plant constituents show low oral toxicity in animal studies
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: May cause mild irritation to mucous membranes, allergies in sensitive individuals
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity from available data
Sensitization: Possible in some individuals with plant allergies
Medical Observation: Prolonged handling or inhalation may aggravate existing respiratory conditions
Ecotoxicity: No specific data for Epimedium extract. Plant-based compounds generally not expected to pose environmental hazards in small quantities
Persistence & Degradability: Biodegradable under normal environmental conditions
Bioaccumulation: Not likely, given plant origin and rapid breakdown
Mobility in Soil: Moderate mobility possible for water-soluble fractions
Other Adverse Effects: Avoid uncontrolled disposal to prevent local effects on aquatic or soil organisms
Waste Treatment: Dispose in accordance with local, regional, and national laws. Material can be sent to landfill if regulations permit
Contaminated Packaging: Rinse thoroughly and recycle or dispose according to local regulations
Special Instructions: Do not incinerate closed containers. Avoid release to environment. Label waste for safe handling
UN Number: Not classified as dangerous goods for transport
Proper Shipping Name: Epimedium Extract, not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Keep packaging intact. Protect from moisture and excessive heat in transit
Environmental Hazards: None known
Inventory Status: Listed or exempt on major chemical inventories (TSCA, EINECS, DSL)
Labelling: Not regulated under GHS/OSHA as hazardous
Health Canada: Regulated as a natural health product
REACH Status: Exempt as plant extract or notified if applicable
Additional Information: Not subject to SARA Title III or CERCLA reporting. Not on the California Proposition 65 list. Import/export restrictions may apply depending on country
