Product Name: Eicosapentaenoic Acid Ethyl Ester
Chemical Formula: C22H34O2, C2H5OH ester
Synonyms: EPA-Ethyl Ester, Ethyl (5Z,8Z,11Z,14Z,17Z)-Icosa-5,8,11,14,17-pentaenoate
CAS Number: 86227-47-6
Intended Use: Pharmaceutical intermediate, dietary supplement component
Manufacturer: [Company contact information and emergency number, as required by jurisdiction]
Physical Hazards: Slightly combustible liquid, may release CO or CO2 under fire conditions
Health Hazards: May cause mild skin or eye irritation on contact, ingestion could lead to gastrointestinal upset, inhalation of vapor may irritate respiratory tract in poorly ventilated spaces
Environmental Hazards: Harmful to aquatic life if released in large volumes, persistent fatty acids may disrupt local microbial populations
Label Elements: Pictograms for skin/eye irritation, aquatic toxicity
Signal Word: Warning
Hazard Statements: Causes mild irritation, harmful to aquatic life
Precautionary Statements: Avoid skin and eye contact, prevent release to waterways, ensure adequate ventilation
Chemical Identity: Eicosapentaenoic Acid Ethyl Ester
Concentration: >95% by weight
Impurities: Trace fatty acid ethyl esters (typically <5%)
Other Additives: None intentional, check certificate of analysis for batch-specific minor components
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present
Skin Contact: Wash skin with plenty of soap and water, seek medical attention if persistent irritation develops
Inhalation: Move person to fresh air, keep comfortable for breathing, consult medical professional for symptoms
Ingestion: Rinse mouth with water, do not induce vomiting, get medical advice if discomfort persists
Notes for Physicians: Treat symptomatically, monitor for allergic reactions or secondary complications
Extinguishing Media: Use foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Strong water jets may spread the liquid
Fire Hazards: Produces dense smoke and toxic fumes including CO, CO2 if burning
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Specific Methods: Cool containers with water spray from safe distance to prevent pressure buildup
Personal Precautions: Wear protective gloves, goggles and clothing, prevent skin and eye contact
Environmental Precautions: Keep out of drains, sewers, and waterways, contain with absorbent material
Methods for Cleaning Up: Use inert materials like sand to soak up spills, place residue in container, ventilate area, dispose of in accordance with local regulations
Handling: Avoid direct contact with skin and eyes, use local exhaust or general ventilation, do not eat, drink or smoke during use
Storage Requirements: Store in cool, dry, well-ventilated area away from strong oxidizers and open flames, tightly closed original container
Incompatible Materials: Strong acids, bases, and oxidizers
Specific End Uses: Follow specific procedures outlined in workplace safety guidelines
Engineering Controls: Provide adequate general and local ventilation
Personal Protective Equipment: Protective chemical-resistant gloves, safety goggles, lab coats
Respiratory Protection: Use a NIOSH/EN-approved respirator if ventilation is inadequate
Hygiene Measures: Wash hands thoroughly after handling, wash contaminated clothing before reuse
Appearance: Pale yellow to clear oily liquid
Odor: Mild, faintly fishy
pH: Not applicable
Melting Point/Freezing Point: Below –45 °C
Boiling Point: Approximately 180–200 °C (decomposes)
Flash Point: Above 160 °C (closed cup method)
Evaporation Rate: Very slow
Explosion Limits: Not explosive
Vapor Pressure: Negligible at room temperature
Density: 0.90–0.92 g/cm3 at 25 °C
Solubility in Water: Insoluble
Partition Coefficient (log Kow): Estimated >5
Auto-Ignition Temperature: Over 300 °C
Viscosity: Viscous liquid at room temperature
Chemical Stability: Stable under ordinary conditions
Possible Hazardous Reactions: Reacts with strong oxidizing agents
Conditions to Avoid: Excess heat, open flames, prolonged exposure to air causing rancidity
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, acrid smoke on combustion
Routes of Exposure: Eye and skin contact, ingestion, inhalation of mist or vapor
Acute Toxicity: Oral LD50 in rats >5000 mg/kg, low acute toxicity
Skin Corrosion/Irritation: Mild, not corrosive
Eye Damage/Irritation: Mild, not classified as damaging
Respiratory or Skin Sensitization: No known sensitizing effect
Chronic Effects: Long-term exposure studies show no significant adverse effects at dietary levels; higher doses may affect lipid metabolism
Carcinogenicity/Mutagenicity/Reproductive Toxicity: Not known to be carcinogenic or mutagenic, reproductive studies in animals show no adverse effects at supplemental levels
Aquatic Toxicity: May be harmful to fish and aquatic organisms if large volumes enter water
Persistence: Biodegradable under aerobic conditions, may take several weeks to fully degrade
Bioaccumulation Potential: High log Kow value, potential for accumulation in aquatic organisms
Soil Mobility: Low mobility, strongly adsorbs to organic matter
Other Adverse Effects: Risk to aquatic environments from high-concentration industrial spills
Waste Treatment Methods: Incinerate under controlled conditions, use a licensed chemical waste disposal contractor
Disposal of Containers: Rinse, triple-wash and puncture before recycling or landfill if permitted
Contaminated Packaging: Handle as hazardous waste, do not reuse for other purposes
Precautions: Prevent entry to sewers, surface or ground waters during disposal
UN Number: Not classified as a dangerous good under UN shipping regulations
Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Labels: None required
Special Precautions for User: During bulk shipping, avoid container rupture and leaks
TSCA: Listed in United States Toxic Substances Control Act Inventory
REACH: Registered under European Union REACH regulation
OSHA: Not specifically regulated as a hazardous substance, general chemical hygiene applies
DSL/NDSL: Listed in Canada Domestic/Non-Domestic Substances List
Other International Regulations: Compliant with pharmaceutical and food supplement registries in major markets, check national legislation for permissible use concentration and labeling