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MSDS for DL-Alpha-Tocopherol Acetate

Identification

Product Name: DL-Alpha-Tocopherol Acetate
Synonyms: Vitamin E Acetate, All-rac-alpha-Tocopheryl Acetate
Chemical Family: Vitamin, Antioxidant
CAS Number: 7695-91-2
EC Number: 231-710-0
Recommended Use: Dietary supplements, Pharmaceutical preparations, Cosmetics
Manufacturer: Manufacturer details provided on commercial packaging
Emergency Contact: Information found on product label

Hazard Identification

GHS Classification: Not classified as hazardous under GHS regulations
Signal Word: Not applicable
Hazard Statements: Product poses low hazard; excessive inhalation or ingestion may cause irritation
Pictograms: None required
Precautionary Statements: Avoid contact with eyes and skin. Prevent dust accumulation. Handle using standard hygiene practices
Potential Health Effects: Inhalation may cause mild respiratory discomfort. Skin contact may result in mild irritation. Eye contact can cause irritation. Oral ingestion likely non-hazardous in typical use

Composition / Information on Ingredients

Chemical Name: DL-Alpha-Tocopherol Acetate
Purity: ≥96%
Common Impurities: Minor levels of related tocopherols and tocopherol esters
Additives: Absent, unless stated on product label
Molecular Formula: C31H52O3
Molecular Weight: 472.75 g/mol

First Aid Measures

General Guidelines: Move affected person away from exposure source. Seek medical attention if symptoms persist
Eye Contact: Rinse immediately with running water for at least 15 minutes; remove contact lenses if present and easy to do
Skin Contact: Wash with soap and water. Remove contaminated clothing
Inhalation: Move to fresh air. Provide supportive care in case of respiratory discomfort
Ingestion: Rinse mouth. Drink water to dilute. Seek medical attention if large quantities consumed or if symptoms develop
Most Important Effects: Possible irritation to eyes, skin, or respiratory tract

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemicals, carbon dioxide, foam, or water spray
Unsuitable Extinguishing Media: Direct water jet may scatter and spread fire
Hazardous Combustion Products: May release carbon monoxide, carbon dioxide, and other irritating fumes
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Flammability: Material can burn if exposed to sustained heat or flame
Special Hazards: Material may splatter if heated above melting point. Can ignite if spilled on hot surfaces
Precautions: Cool exposed containers with water. Prevent runoff into drains

Accidental Release Measures

Personal Precautions: Avoid creating dust. Wear appropriate protective clothing, gloves, goggles
Environmental Precautions: Prevent entry into waterways or sewers. Inform authorities in case of large spill
Methods for Cleanup: Contain spilled material. Absorb with inert material such as sand or vermiculite. Collect and place in suitable containers for disposal
Decontamination: Wash spill site with water and detergent. Ventilate area
Disposal of Waste: Dispose in accordance with local, state, and federal regulations

Handling and Storage

Handling: Avoid dust generation. Use only in well-ventilated areas. Never eat, drink, or smoke while handling
Technical Measures: Earth or bond containers when transferring material
Storage Conditions: Keep container tightly closed in a dry, cool, and well-ventilated place.
Incompatible Materials: Strong oxidizers, acids
Storage Temperature: Ideally between 15°C and 25°C; protect from moisture, heat, direct sunlight
Special Requirements: Keep away from food and feedstuffs. Store in original packaging

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limit established by OSHA, NIOSH, or ACGIH
Engineering Controls: Use local exhaust ventilation or process enclosures to minimize dust
Personal Protective Equipment: Safety goggles, chemical resistant gloves, protective clothing
Respiratory Protection: Dust mask or respirator recommended if airborne concentration increases
Hygiene Measures: Wash hands thoroughly after handling. Remove contaminated clothing before leaving work area

Physical and Chemical Properties

Appearance: Clear, slightly yellow, viscous oil
Odor: Faint, characteristic odor
Odor Threshold: Not relevant
pH: Not applicable (insoluble in water)
Melting Point/Freezing Point: -27°C to -20°C
Boiling Point: >200°C
Flash Point: Approximately 200°C (392°F)
Evaporation Rate: Not measurable (non-volatile oil)
Flammability: Not highly flammable, but combustible
Vapor Pressure: <0.01 mmHg (@ 20°C)
Vapor Density: Not determined
Relative Density: About 0.95-0.97 g/cm³ (@ 20°C)
Solubility: Insoluble in water; soluble in fats and oils, ethanol, benzene
Partition Coefficient (n-octanol/water): Log Kow > 8.5
Auto-ignition Temperature: >400°C
Decomposition Temperature: >200°C
Viscosity: Viscous liquid at room temperature

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Low under normal conditions
Conditions to Avoid: Exposure to strong heat, sunlight, oxidizing agents
Incompatible Materials: Strong acids, alkalis, oxidants
Hazardous Decomposition Products: Thermal decomposition may yield irritating or toxic fumes including carbon oxides
Polymerization: Will not occur under normal circumstances

Toxicological Information

Acute Toxicity: LD50 (oral, rat): >7000 mg/kg; considered low toxicity
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Possible Effects: Skin or eye irritation with direct and prolonged exposure
Symptoms: Redness, stinging sensation, coughing if inhaled
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity
Sensitization: Not a skin sensitizer based on available studies
Additional Information: Large oral doses over extended periods may interfere with absorption of other fat-soluble vitamins

Ecological Information

Aquatic Toxicity: Low toxicity for aquatic life expected; not acutely hazardous
Persistence and Degradability: Expected to degrade slowly in the environment
Bioaccumulation: High potential due to hydrophobic nature (log Kow > 8.5)
Mobility in Soil: Low mobility; binds strongly to organic material
Other Adverse Effects: No significant negative environmental impact reported with typical use and disposal patterns

Disposal Considerations

Waste Disposal Methods: Dispose of product in accordance with local, state, and federal regulations
Contaminated Packaging: Empty containers completely before disposal; rinse if possible
Recommended Disposal: Sanitary landfill, incineration in accordance with regulations
Precautions: Prevent release to environment beyond permitted limits

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: None assigned
Packing Group: None
Marine Pollutant: No
Special Precautions: Protect from physical damage and moisture during transport

Regulatory Information

TSCA Status: Listed in United States TSCA inventory
DSL Status: Listed in Canadian Domestic Substances List
REACH Status: Registered in accordance with European REACH requirements
US Federal Regulations: Not listed as a hazardous chemical under SARA Title III
California Proposition 65: Not listed as a chemical known to cause cancer or reproductive harm
Labeling Requirements: Not required for consumer packaging, but provided for bulk supply
Other Regulations: Subject to requirements and guidelines in food, pharmaceutical, and cosmetic sectors; always follow label and regulatory instructions for specific application