Product Name: Disodium 5'-Ribonucleotide I+G
Chemical Formula: C10H11N4Na2O8P
CAS Number: 4691-65-0 (Disodium 5'-Inosinate), 4691-63-8 (Disodium 5'-Guanylate)
Synonyms: I+G, E635, Disodium 5'-ribonucleotides, Flavour enhancer blend
Recommended Use: Food additive, flavour enhancer
Supplier Information: Manufacturer or broker details should be included with company name, address, emergency contact, and business telephone.
Classification: Not classified as hazardous according to OSHA Hazard Communication Standard (29 CFR 1910.1200).
GHS Label: None required
Hazard Statements: May cause eye irritation; dust may irritate respiratory system.
Signal Word: None
Precautionary Statements: Avoid inhalation of dust. Avoid contact with eyes. Wash thoroughly after handling.
Pictograms: None mandated
Other Hazards: In large quantities, ingestion can lead to mild gastrointestinal upset.
Chemical Name: Disodium 5'-Inosinate
Concentration: 49-51%
Chemical Name: Disodium 5'-Guanylate
Concentration: 49-51%
Impurities: Typical for fermentation or chemical synthesis routes; negligible impact on health or safety.
Additives: None.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical help if irritation lingers.
Skin Contact: Remove contaminated clothing, wash skin with soap and water, if irritation develops get medical advice.
Inhalation: Move to fresh air, keep at rest, get help if symptoms such as coughing or throat irritation develop.
Ingestion: Rinse mouth, do not induce vomiting, seek medical help if large quantities are swallowed or if symptoms follow.
Suitable Extinguishing Media: Use water spray, foam, dry chemical or CO2 for small fires. Choose agent suitable for surrounding materials.
Hazards from Chemical: Combustion produces CO2, possible generation of nitrogen oxides and other standard organic combustion products.
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing.
Specific Methods: Cool surrounding containers with water spray to prevent pressurized rupture.
Personal Precautions: Wear dust mask, safety goggles, gloves.
Environmental Precautions: Avoid discharge to drains, waterways, soil—clean up spills quickly using damp methods.
Methods for Cleaning Up: Sweep or vacuum without creating dust, place in labeled waste container, wash area with water.
Notification: Notify local authorities if significant material enters watercourse or sewers.
Precautions for Safe Handling: Avoid generating dust; keep containers tightly closed; do not eat, drink, or smoke while handling the powder.
Safe Storage Conditions: Store in cool, dry, well-ventilated area; keep container tightly sealed.
Incompatible Materials: Strong oxidizing agents.
Special Requirements: Use only with adequate ventilation.
Exposure Limits: No occupational exposure limits assigned.
Engineering Controls: Use local exhaust ventilation if dust formation is expected. Eyewash stations recommended.
Personal Protective Equipment: Dust mask, nitrile gloves, safety goggles, lab coat.
Hygiene Measures: Wash hands before breaks and after handling; keep work area clean.
Appearance: White to off-white crystal powder
Odor: No distinctive scent
pH (1% Solution): 7-8
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility: Fully soluble in water
Flash Point: Not flammable under standard testing
Partition Coefficient (n-octanol/water): Not determined
Vapor Pressure: Not relevant
Chemical Stability: Stable under normal conditions.
Conditions to Avoid: Excessive heat, high humidity, open flames.
Materials to Avoid: Strong oxidizers.
Hazardous Decomposition: CO2, nitrogen oxides under fire conditions.
Hazardous Polymerization: Will not occur.
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg (low acute toxicity).
Skin Corrosion/Irritation: Not an irritant.
Eye Damage/Irritation: Mild, transient irritation possible.
Respiratory or Skin Sensitization: Not sensitizing.
Chronic Effects: At typical levels, not linked to chronic health issues. Large amounts may aggravate kidney or gout in sensitive people.
Carcinogenicity: Not listed by IARC, NTP, OSHA.
Mutagenicity and Teratogenicity: No evidence in scientific studies.
Aquatic Toxicity: Not considered toxic to aquatic life, rapidly biodegradable.
Environmental Persistence: Breaks down quickly in nature.
Bioaccumulation: Not expected.
Soil Mobility: Highly soluble, unlikely to accumulate in soil.
Other Adverse Effects: Product poses minimal risk to environment in practical use or accidental release.
Waste Treatment: Dispose through authorized waste management provider; follow local, regional, national, and international regulations.
Methods of Disposal: Can be incinerated or landfilled in accordance with applicable guidelines.
Contaminated Packaging: Containers must be emptied and rinsed; recyclable or disposed of according to regulations.
Special Precautions: Do not allow large quantities to enter waterways.
UN Number: Not regulated as a hazardous product for transport.
Proper Shipping Name: Disodium 5'-Ribonucleotide I+G
Transport Hazard Class: Not classified as dangerous
Packing Group: Not required
Environmental Hazards: Not marine pollutant
Special Precautions for User: No special requirements for safe transport under standard conditions.
Regulatory Status: Approved as a food additive in many countries, including US (FDA, 21 CFR 172.896), EU (E635).
TSCA Status: Listed as a food additive substance.
OSHA: Not a hazardous chemical.
WHMIS (Canada): Not controlled.
Other National Inventories: Listed on AICS, DSL, ENCS, IECSC.
Labeling Requirements: Ensure proper food labeling for consumer transparency.
Restrictions: Dosage limits apply based on country’s food regulations; not for use outside authorized uses.