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Material Safety Data Sheet – Dextrose Anhydrous

1. Identification

Product Name: Dextrose Anhydrous
Chemical Name: D-glucose
Synonyms: Corn sugar, Grape sugar, Blood sugar
CAS Number: 50-99-7
Recommended Use: Food industry, pharmaceuticals, fermentation, laboratory reagent
Supplier Information: Manufacturer or distributor name, full address, emergency telephone number, contact person
Emergency Overview: Fine white crystalline solid, sweet taste, no significant odor

2. Hazard Identification

GHS Classification: Not classified as hazardous according to GHS
Label Elements: No hazard pictogram, no signal word, no hazard statement required
Potential Health Effects: Inhalation of dust may cause mild respiratory irritation. Contact may cause slight eye discomfort. Dust may dry or irritate skin with prolonged exposure. Not considered toxic or corrosive.
Environmental Effects: Large releases may impact aquatic systems by contributing nutrient load
Physical Hazards: Dust may form explosive mixtures with air in rare high-dust scenarios
Precautionary Statements: Avoid breathing dust. Use personal protective equipment as required. Prevent large quantities from entering drains.

3. Composition / Information on Ingredients

Chemical Identity: Dextrose Anhydrous
Common Name: D-glucose
CAS Number: 50-99-7
EC Number: 200-075-1
Concentration: >99% purity
Impurities: Trace amounts of water, maltose, or other saccharides from raw source
Additives: None in food or laboratory grades

4. First Aid Measures

Inhalation: Move exposed person to fresh air. Rinse nose and mouth if irritation occurs. Seek medical attention if symptoms persist.
Skin Contact: Wash with plenty of soap and water. Remove contaminated clothing and wash before reuse. Moisturize skin if dryness develops.
Eye Contact: Rinse eyes thoroughly with clean running water for several minutes. Lift eyelids to ensure thorough rinsing. Seek medical attention if discomfort remains.
Ingestion: Not considered hazardous if swallowed in typical amounts. If large amount consumed and discomfort results, seek medical advice.
Most Important Symptoms: Mild irritation to respiratory system, skin, or eyes in sensitive individuals
Notes to Physician: Treat symptomatically. Targeted intervention not typically required.

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide. Use method appropriate for surrounding fire.
Unsuitable Media: None known for product; avoid direct water jet if dusty.
Specific Hazards: Fine dust in air at high concentrations may create explosive conditions.
Hazardous Combustion Products: Carbon oxides (CO, CO2)
Special Protective Equipment: Standard firefighter gear, self-contained breathing apparatus in large fires
Fire-Fighting Procedures: Fight fire from upwind position. Prevent runoff from fire control entering sewers or waterways. Move product away from fire if it can be done safely.

6. Accidental Release Measures

Personal Precautions: Wear appropriate dust mask and safety goggles. Minimize airborne dust formation. Avoid unnecessary contact.
Environmental Precautions: Prevent entry of spillage into drains and surface water, especially in large quantities.
Clean-Up Methods: Sweep up and place in a suitable, labeled container. Shovel material into closed container for reuse or disposal. Vacuum up remaining dust with equipment fitted with HEPA filter. Wash spill area with water if needed.
Reference to Other Sections: For personal protective equipment see Section 8; for disposal see Section 13.

7. Handling and Storage

Precautions for Safe Handling: Handle product in well-ventilated areas. Avoid generating and breathing dust. Use equipment and procedures that minimize dust formation. Maintain good housekeeping. Keep containers tightly sealed.
Conditions for Safe Storage: Store in dry, cool, well-ventilated location. Keep container closed when not in use. Avoid temperature extremes and sources of ignition. Separate from strong acids, oxidizers.
Packaging Materials: Use food grade or chemical resistant containers depending on intended end use.
Other Advice: Inspect regularly for spillage or leaks. Product is hygroscopic and absorbs moisture from air, so minimize exposure.

8. Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific exposure limits set for dextrose anhydrous; use general nuisance dust limits (e.g., OSHA PEL: 15 mg/m³ total dust, 5 mg/m³ respirable fraction)
Engineering Controls: Provide adequate ventilation or dust extraction, especially during bulk handling.
Respiratory Protection: Use dust mask or NIOSH-approved respirator if dusting is likely to exceed limits.
Eye Protection: Safety goggles or glasses when handling large quantities or in dusty environment.
Skin Protection: Wear protective gloves if handling for extended periods or if skin is sensitive.
Hygiene Measures: Wash hands after use. Do not eat or drink near working area. Change and wash contaminated clothing before reuse.
Other PPE: Use coveralls if systematic large-scale handling is part of the job.

9. Physical and Chemical Properties

Appearance: White crystalline powder or granules
Odor: Odorless or faintly sweet
Odor Threshold: Not established
pH: Approx. 6.0–7.5 (10% solution in water)
Melting Point: Approximately 146°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Evaporation Rate: Not volatile
Flammability (Solid/Gas): Not classified as flammable, but dust form can be explosive
Upper/Lower Flammable Limits: Not established
Vapor Pressure: Negligible
Vapor Density: Not applicable
Relative Density: Around 1.5 g/cm³
Solubility: Soluble in water (approx. 80 g/100 mL at 25°C); practically insoluble in alcohol and ether
Partition Coefficient (n-octanol/water): Not measured
Autoignition Temperature: Approximately 420°C
Decomposition Temperature: Above 160°C
Viscosity: Not applicable for solid

10. Stability and Reactivity

Chemical Stability: Stable under recommended conditions of storage and use
Reactivity: Will not undergo hazardous polymerization
Conditions to Avoid: Avoid high humidity, excessive temperatures, sources of ignition
Incompatible Materials: Strong oxidizing agents, concentrated acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide if heated or burned
Possibility of Hazardous Reactions: Dust can form explosive mixtures with air under certain conditions.

11. Toxicological Information

Acute Toxicity: No acute oral, dermal, or inhalation toxicity at expected exposure levels; LD50 (oral, rat) >10,000 mg/kg
Skin Corrosion/Irritation: May cause mild irritation with prolonged contact on sensitive individuals
Serious Eye Damage/Irritation: May cause mild transient irritation
Respiratory/Skin Sensitization: Not a known sensitizer
Germ Cell Mutagenicity: Not classified as mutagenic
Carcinogenicity: IARC, NTP, OSHA do not classify dextrose as a carcinogen
Reproductive Toxicity: Not expected to impair fertility or cause developmental harm
Specific Target Organ Toxicity: No specific target organ identified
Signs and Symptoms: Large doses ingested may raise blood sugar, of concern in individuals with diabetes
Medical Conditions Aggravated: Diabetes mellitus and other disorders involving impaired glucose metabolism

12. Ecological Information

Ecotoxicity: Not toxic to aquatic or terrestrial life at expected concentrations; easily biodegradable
Persistence and Degradability: Rapidly decomposed by bacteria and other microbes in natural environments
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: High mobility in water; readily dissolves and disperses
Other Adverse Effects: Large releases to water may cause temporary oxygen depletion due to microbial activity

13. Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations. Product may generally be disposed of as non-hazardous solid waste. Uncontaminated product can often be used or recycled.
Packaging Disposal: Empty bags or containers should be recycled or disposed of safely following local regulatory guidance.
Special Instructions: Avoid releasing large quantities into drains or surface water. Clean up spills promptly to minimize risk of dust and prevent attraction of pests.

14. Transport Information

UN Number: Not classified as dangerous goods
UN Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not applicable
Packing Group: Not regulated
Environmental Hazards: Not a marine pollutant
Special Precautions: Store in sealed containers during transport to prevent moisture absorption and spillage.
Land, Sea, Air Transport: No special transport requirements under ADR/RID, IMDG, IATA regulations

15. Regulatory Information

Safety, Health and Environmental Regulations: Dextrose anhydrous is not controlled under major chemical regulations such as TSCA, REACH, WHMIS, or Australian Hazardous Substances Code
FDA Status: Recognized as GRAS (Generally Recognized as Safe) when used in food products in the United States
Labelling: No hazard labelling required under GHS or EU CLP guidelines
Inventory Listing: Listed in chemical inventories (US TSCA, EU EINECS, Canada DSL, Australia AICS, Japan ENCS, etc.)
Other Legal Requirements: Observe local, national and international regulations for transportation, handling, and waste disposal.