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Material Safety Data Sheet – Dehydroacetic Acid

Identification

Product Name: Dehydroacetic Acid
Chemical Name: 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione
Common Synonyms: DHA, p-Anisylacetone
Molecular Formula: C8H8O4
Molecular Weight: 168.15 g/mol
CAS Number: 520-45-6
Recommended Use: Food preservative, cosmetic ingredient, fungicide
Supplier Details: Manufacturer contact name, address, phone number, and emergency contact included on container label
Emergency Phone: Refer to country or region specifics, but a 24-hour helpline remains a necessity

Hazard Identification

GHS Classification: Eye irritation (Category 2), Skin irritation (Category 2)
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Wear protective gloves and eye protection, avoid breathing dust, seek medical advice if symptoms persist
Routes of Exposure: Inhalation, skin and eye contact, ingestion

Composition / Information on Ingredients

Component: Dehydroacetic Acid
Concentration: 99% or higher
Chemical Identity: C8H8O4
CAS Number: 520-45-6

First Aid Measures

Inhalation: Move exposed person to fresh air. Provide oxygen if breathing becomes difficult. Seek medical attention if respiratory symptoms persist.
Skin Contact: Remove contaminated clothing. Wash affected area with plenty of water and mild soap. If skin irritation or rash occurs, get medical advice.
Eye Contact: Rinse cautiously with water for several minutes, lifting eyelids to ensure thorough flushing. Remove contact lenses if present and easy to do. Continue rinsing, seek medical attention.
Ingestion: Rinse mouth with water if the exposed person is conscious. Do not induce vomiting. Seek immediate medical attention.

Fire-Fighting Measures

Suitable Extinguishing Media: Foam, dry chemical, CO2, water spray
Specific Hazards from Combustion: Emits irritating or toxic fumes under fire conditions—possible carbon oxides
Protective Equipment: Firefighters require full protective gear including self-contained breathing apparatus
Fire-Fighting Instructions: Move containers from danger area if possible, use water spray to cool fire-exposed containers, avoid inhaling fumes

Accidental Release Measures

Personal Precautions: Use personal protective equipment, ensure adequate ventilation, avoid creating dust
Environmental Precautions: Prevent spillage from entering drains, surface water, or groundwater
Methods for Cleaning Up: Collect spillage mechanically, use non-sparking tools for dry material, place collected powder in closed containers for proper disposal, clean residue using water while minimizing water runoff

Handling and Storage

Safe Handling Guidelines: Handle with care in well-ventilated areas, minimize dust generation, wear protective equipment
Storage Recommendations: Keep container tightly closed, store in cool, dry, well-ventilated area, avoid exposure to heat and direct sunlight, keep apart from strong oxidizers and incompatible substances, use only approved containers

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established workplace exposure limits
Engineering Controls: Local exhaust ventilation recommended, eyewash stations, safety showers available
Personal Protective Equipment: Safety goggles, chemical-resistant gloves, protective clothing, approved respirators when dust exposure is likely
Hygiene Practices: Wash hands and face thoroughly after handling, remove contaminated clothing and wash before reuse, avoid eating, drinking, or smoking in work area

Physical and Chemical Properties

Appearance: White to slightly yellow crystalline powder
Odor: Faint characteristic odor
Melting Point: 109–111°C
Boiling Point: Decomposes
Vapor Pressure: Not significant at ambient temperature
Solubility: Slightly soluble in water, soluble in ethanol, acetone
pH: Approximately 2.6 (1% in water)
Flash Point: Above 150°C (estimated)
Autoignition Temperature: Data not available
Density: 1.336 g/cm³
Partition Coefficient (n-octanol/water): Log Kow approximately 0.43
Explosive Properties: Not explosive
Oxidizing Properties: Not oxidizing

Stability and Reactivity

Chemical Stability: Stable under normal conditions of use and storage
Reactivity: Avoid contact with strong oxidizing agents, strong bases
Decomposition Products: Thermal decomposition releases carbon monoxide, carbon dioxide, and organic vapors
Hazardous Reactions: No hazardous polymerization expected under standard conditions

Toxicological Information

Acute Toxicity: Oral LD50 in rats: about 2500 mg/kg
Skin Corrosion/Irritation: Causes moderate skin irritation
Eye Damage/Irritation: Causes serious eye irritation
Respiratory Sensitization: May cause mild respiratory irritation when dust is inhaled
Chronic Toxicity: No evidence of carcinogenicity or reproductive toxicity
Mutagenicity: Negative in standard in vitro assays
Potential Health Effects: Prolonged or repeated skin contact may generate dryness or cracking; inhalation of dust could trigger coughing or throat discomfort

Ecological Information

Aquatic Toxicity: Moderately toxic to aquatic life - freshwater fish LC50 (96h) > 100 mg/L
Persistence and Degradability: Biodegradable - breaks down under standard conditions
Bioaccumulative Potential: Low potential, low log Kow value
Mobility in Soil: Mobile enough to migrate in moist environments
Other Information: Runoff to waterways should be avoided to minimize risk to non-target organisms

Disposal Considerations

Product Disposal: Follow local, regional, and national regulations, treat as hazardous waste if contaminated
Contaminated Packaging: Empty containers thoroughly, triple rinse, dispose as regulated industrial waste
Methods: Incineration under controlled conditions preferred if available, landfill permitted with legal controls

Transport Information

UN Number: Not classified as dangerous goods
Transport Hazard Class: Not regulated for ADR/RID/IMDG/IATA
Packing Group: None assigned
Special Precautions: Keep containers securely closed, store away from foodstuffs
Environmental Hazards: Not considered marine pollutant

Regulatory Information

Labelling Requirements: Complies with CLP, OSHA GHS regulations
Inventory Listings: Present on TSCA, REACH, DSL, EINECS, AICS, NZIoC, PICCS, KECL
Compliance Statements: Approved for use in food and cosmetics under IFR and EFSA with specified maximum concentrations
Other Regulatory Data: Not listed as a controlled substance or carcinogen by NTP, IARC, OSHA or other international agencies
Restrictions: Observe use limitations set by regional cosmetic and food safety authorities