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D-Calcium Pantothenate: Past, Present, and What Lies Ahead

Historical Development

Since the mid-20th century, D-Calcium Pantothenate has played an ongoing role in both the pharmaceutical and food industries. Researchers first isolated pantothenic acid in the 1930s, naming it after the Greek word “pantothen,” meaning “from everywhere.” This vitamin turned out to be widespread in foods, from eggs to avocados. With time, scientists began seeking a more stable form that could withstand processing and storage. Out of those efforts emerged D-Calcium Pantothenate, a salt form that helped extend shelf life, improve solubility, and secure vitamin B5’s spot in a list of necessary nutrients for both human and animal health. By the 1950s, it became a common sight in multivitamin formulations, and pharmaceutical houses recognized its popularity as a commercial ingredient that supported everything from metabolism to skin health, opening the door to extensive research and mass production.

Product Overview

D-Calcium Pantothenate has found its way into many supplement bottles and fortification mixes. It acts as a vital source of vitamin B5, an essential nutrient for humans and animals. Manufacturers rely on it to provide consistent potency in their products, partly due to its robust nature—it will not break down when exposed to light or heat, a major advantage during transportation and storage. D-Calcium Pantothenate’s bioavailability means that after ingestion, the body can readily use it, converting it into coenzyme A, which powers metabolic pathways from energy production to hormone synthesis. As food regulation standards continue to evolve, D-Calcium Pantothenate’s inclusion as a food additive underscores its broad acceptance and the ongoing demand for well-researched nutritional ingredients.

Physical & Chemical Properties

On the lab bench, this compound appears as a white, odorless powder that dissolves easily in water but resists breakdown in oil. Its molecular formula, C18H32CaN2O10, packs calcium into the pantothenate backbone, which improves its handling properties for manufacturers and formulators. Chemists appreciate its relatively high stability; it holds up to environmental stress that would otherwise destroy its parent compound, pantothenic acid. During my time working with supplement start-ups, I’ve seen how that stability reduces loss during mixing, granulation, and tablet compression, which keeps product quality high from batch to batch. Pharmaceutical-grade D-Calcium Pantothenate typically includes only trace amounts of impurities, keeping up with strict global standards. That high degree of purity is necessary for infant formulas and intravenous solutions, where margins for error run close to zero.

Technical Specifications & Labeling

Industry standards demand a precise set of technical specifications for D-Calcium Pantothenate. Purity should usually exceed 99%, and particle size distribution stays tight to allow uniform blending. Labels often list it as “Vitamin B5 (as D-Calcium Pantothenate),” providing daily value percentages set by organizations like the FDA or EFSA. The specifications include moisture content, heavy metal limits, and microbial controls. Each batch travels with a certificate of analysis, offering transparency for both customers and regulators. In today’s landscape where consumers look for “clean label” assurances, verifying the purity and traceability of the raw ingredient sits high on the priority list. Manufacturers also address allergen status, confirming that the product is free of gluten, soy, and other problematic traces that might impact sensitive populations. Batch numbers and expiration dates help trace any recalls or quality concerns quickly.

Preparation Method

Production of D-Calcium Pantothenate typically involves chemical synthesis rather than extraction from natural sources, as scaling from plants or animal tissues would be cost-prohibitive and unsustainable. Most processes start with β-alanine and pantoic acid, synthesized in the lab and then reacted together. The resulting compound joins with calcium salts, usually calcium carbonate or calcium hydroxide, to form D-Calcium Pantothenate. Highly controlled reaction temperatures, pH levels, and purification steps help remove side-products. From my own experience working with finished product testing, I’ve seen that even small changes in raw material quality or pH during synthesis can cause purity to dip, so the process benefits from careful oversight and skilled technicians. Final product passes through multiple filtration and drying stages before reaching the market.

Chemical Reactions & Modifications

Beyond simple synthesis, chemists sometimes modify D-Calcium Pantothenate for specific uses. It resists hydrolysis under normal conditions, but acidic or enzymatic treatments can cleave it back into free pantothenic acid in the digestive tract. Under industrial settings, the molecule’s reactivity with other supplement ingredients, such as minerals or botanical extracts, receives careful study to prevent unwanted degradation or reduced absorption. Encapsulation techniques help shield it from moisture and heat, especially in high-speed tablet lines where degradation could reduce vitamin activity. Advances in microencapsulation might improve targeted release in the gut or enhance stability in complex supplement blends, something product formulation teams continue to push for.

Synonyms & Product Names

Across literature and product labels, D-Calcium Pantothenate gets called by several names. The most common synonyms include “Calcium D-pantothenate,” “Pantothenic acid calcium salt, D-isomer,” or simply “Vitamin B5.” Global supplement markets sometimes display alternate translations or abbreviations, but the backbone structure remains the same. Pharmaceutical and regulatory documents use the official international nonproprietary name to prevent confusion. Brands and contract manufacturers may develop their own trademarked blends but typically reveal the source ingredient on nutritional facts panels to maintain transparency and comply with labeling laws. For years, this habit has helped build trust between raw material suppliers and finished product companies.

Safety & Operational Standards

D-Calcium Pantothenate’s safety profile stands out as well established. Toxicological reviews and decades of supplementation prove its low risk at recommended daily dosages. Food and pharmaceutical manufacturers rely on Good Manufacturing Practices (GMP) to keep contamination risks low. Manufacturing facilities face routine inspections from FDA or analogous authorities, with strict record-keeping and environmental monitoring. The role of independent third-party testing increases as consumers demand transparent supply chains in their vitamins and supplements. Any process deviations often trigger prompt investigations, and recall protocols get practiced regularly. In the facility environment, workers must wear gloves, masks, and coats to avoid breathing in or touching excess dust, as long-term exposure can irritate the respiratory tract or skin. Proper storage means avoiding moisture and high heat, which could degrade the active content and compromise testing results.

Application Area

You might recognize D-Calcium Pantothenate in a multivitamin, but its reach goes much further. Food companies often turn to it for fortifying cereals, breads, sports drinks, and infant formulas. Livestock and pet food industries rely on it to balance essential vitamin B5 needs for animal health, supporting growth, fertility, and immune strength. On the personal care front, hair and skin formulations leverage its moisturizing and regenerative properties—shampoos, conditioners, and facial creams advertise the addition of “panthenol,” a pro-vitamin derived from the same molecule. Pharmaceutical companies add it to injection preparations and oral wellness products. Health authorities and dieticians point to clinical results that link B5 deficiency to fatigue, mood swings, and skin problems, justifying its widespread use in both preventative and clinical care.

Research & Development

Over recent decades, researchers continue to look for undiscovered applications and improved delivery forms. Studies explore its role in metabolic health, adrenal support, and wound healing, with early results suggesting benefits beyond basic deficiency prevention. Universities and research labs dig into molecular mechanisms—how exactly does this vitamin support skin barrier function, or could it serve as a supportive element for nerve pain? Product developers test new encapsulation formats or co-formulations with other B-vitamins to address absorption issues and improve compliance. Technology advances in synthetic biology might offer biosynthetic production alternatives that reduce the need for traditional chemical synthesis, which could decrease waste and energy consumption over time. Consumer feedback and clinical data alike steer the next rounds of formula improvements.

Toxicity Research

Toxicologists have spent years evaluating potential safety issues from D-Calcium Pantothenate. Reports show it carries an extremely low risk of acute toxicity, mostly because the body flushes out excess pantothenic acid. High-dose, long-term supplementation trials in both humans and animals point to mild side effects such as stomach upset, rather than any serious risk. Regulatory agencies typically classify it as “Generally Recognized as Safe” (GRAS) when used at accepted dosages. That said, attention must stay sharp with any supplement, especially in special populations like pregnant individuals or infants. Testing focuses on chronic exposure, allergens, and impurities like heavy metals, so ongoing review remains part of the routine at manufacturing sites.

Future Prospects

There’s every indication that D-Calcium Pantothenate will keep its central role in health and nutrition. Consumer trends push for “science-backed” supplements and fortified foods that deliver measurable benefits. More advanced formulations could focus on personalized nutrition, delivering precise dosages in targeted forms. Sustainability questions fuel research into low-waste production and plant-based or fermentation-based alternatives. Global regulatory shifts drive continuous improvement in traceability and transparency, while companies that invest in cleaner, greener processes set new industry standards. Research into the gut microbiome, mental health, and skin support could reveal new uses for D-Calcium Pantothenate in combination with other emerging bioactives. As the industry faces supply chain disruptions and rising demand, those able to innovate on manufacturing, safety, and efficacy will shape the next era for this humble but powerful micronutrient.




What is D-Calcium Pantothenate used for?

What’s the Role of D-Calcium Pantothenate?

D-Calcium Pantothenate crops up on vitamin bottles, energy drinks, and even fortified breakfast cereal. It sounds like a science lab term, but at its core, it’s just a stable, often-used form of vitamin B5. Our bodies break it down and use it for a bunch of important business. I see a lot of people miss this because the ingredient has a complicated name, but its job is to keep us ticking every single day.

This compound helps turn carbohydrates, fats, and proteins into fuel. We eat a snack, and the nutrients don’t automatically become energy. D-Calcium Pantothenate acts like the team foreman, running the energy conversion factory in our cells. That makes a big difference for anyone who’s chronically tired or trying to keep up with a crazy schedule. I’ve noticed on afternoons where I don’t eat well, my focus slips, and my energy lags. B vitamins, including pantothenate, help keep that at bay.

Why Add It to Food and Supplements?

It’s tough to eat perfectly. Many people don’t get enough B5 from diets heavy on fast food, white bread, or processed snacks. D-Calcium Pantothenate sticks around better than regular B5 in tablet form, so food makers turn to it to boost nutrition in things like multivitamins, power bars, sports drinks, baby formula, and pet food. I’ve seen it listed in almost every supplement I’ve examined in a pharmacy aisle. That’s because deficiencies can lead to mood problems, tingling feet, and even muscle cramps. Boosting intake often helps folks who feel constantly sluggish.

What Does the Science Say?

Pantothenic acid has been studied for decades. The National Institutes of Health points to its role in hormone creation and metabolism. People need it for making red blood cells and supporting healthy digestion. The calcium salt version stands out for staying shelf-stable and easy to blend into products, so it pops up almost everywhere. D-Calcium Pantothenate blends right in without breaking down quickly, making it useful for manufacturers and good for consumers who don’t eat perfectly every meal.

Daily Health and Real-Life Impact

Daily life doesn’t offer much space for tracking every vitamin. Most folks I know just want to feel better and avoid doctor visits. By shoring up gaps with D-Calcium Pantothenate, people get a basic insurance policy for their nerves, energy, and stress response. Athletes, busy parents, and older adults can especially benefit. In one study in the Journal of Nutrition, participants who got enough B5 performed better on mental tasks and felt less tired. That lines up with many anecdotes I hear from people who start taking B-complex supplements.

Pushing for Better Nutrition

D-Calcium Pantothenate’s presence alone doesn’t change poor eating habits, but it offers a safety net. Schools, food banks, and community clinics could use more education and food enrichment. Healthy lunches and accessible multivitamins fight off the slow creep of fatigue and irritability. I always encourage reading labels, looking for B5 or its salt listed, and eating a mix of fresh and fortified foods. If more people understood what it does and why it matters, we’d have fewer folks feeling exhausted and more enjoying real energy from their food.

What are the benefits of taking D-Calcium Pantothenate?

Crucial Fuel for Your Cells

D-Calcium Pantothenate, also called vitamin B5, shows up in nearly every cell in your body. It helps turn the food you eat into the fuel that keeps you moving, thinking, and recovering. Add this vitamin to your routine, and you help your body process fats, carbohydrates, and proteins more efficiently. If you skip out on B5, you can start feeling tired, sluggish, or even cranky. I’ve seen folks chalk up low energy to age or bad sleep, but sometimes, the real reason links back to these tiny gaps in the diet.

Boosts Wound Healing and Skin Health

Anyone who works with their hands or faces sun, wind, or city air knows what a relief it feels like to have soft, strong skin. D-Calcium Pantothenate plays a direct role in building healthy skin cells. Researchers at the University of Maryland Medical Center point out that B5 helps wounds heal faster by supporting new cell growth. Some topical creams even use it as a main ingredient. At home, I’ve noticed taking enough B5 in my diet means fewer dry spots through winter and less time waiting for cuts to close up.

Powering Brains under Stress

Busy work weeks, tight deadlines, family schedules—stress sneaks up, then lingers for days. Vitamin B5 supports the nervous system by helping make key neurotransmitters like acetylcholine, used for memory and focus. A study published in the journal “Nutrients” notes that B5 helps maintain mental sharpness—especially under pressure. Every day in my own life, the difference between clear thinking and brain fog often boils down to nutrition. Reaching for more whole grains, eggs, and vegetables rich in B5 has boosted my concentration during those “can’t fail” moments.

Supporting Heart Health

Healthy eating and regular movement go a long way toward protecting the heart. D-Calcium Pantothenate supports these efforts. Its role in fat metabolism means it influences cholesterol levels. Some research shows that getting enough B5 can lead to better balance between harmful and helpful cholesterol over time. If you have a family history of heart trouble, making sure you aren’t short on B5 is a simple move with a potential payoff.

Keeping the Body’s Engine Running Smoothly

You can’t skip out on micronutrients and expect your body to run properly. One interesting fact: D-Calcium Pantothenate helps create red blood cells. These cells carry oxygen to every muscle, organ, and tissue. If you’ve ever gone through a period where you felt tired after a small hill or a single flight of stairs, low B5 could be a culprit. In my late twenties, after weeks of living on takeout, I felt drained all the time. Once I added more nutrient-rich foods and a multivitamin, my body snapped back fast.

Filling the Gaps: Diet and Supplements

Most folks can meet their B5 needs with a varied diet—think sweet potatoes, chicken, mushrooms, and lentils. Still, kids, older adults, vegans, or people with restrictive diets sometimes miss the mark. In these cases, a supplement can help. The key: balance. Talking with a healthcare provider can help find the right dose, since too much of any vitamin sometimes causes its own problems.

Are there any side effects of D-Calcium Pantothenate?

The Role of D-Calcium Pantothenate in Everyday Life

D-Calcium Pantothenate might not ring a bell for everyone, but it quietly shows up in plenty of supplements and fortified foods. People take it because it delivers vitamin B5, which plays a part in how the body gets energy from food. Growing up, I always saw a lineup of multivitamin bottles in my parents’ medicine cabinet, and vitamin B5 rarely got much attention. No spark or headline like vitamin C or D, but still, it showed up as a daily pill for a reason.

Possible Side Effects and Why They Happen

Most people don’t get hit by serious side effects when they keep their dose in the recommended range. Vitamin B5 is water-soluble, which means the body gets rid of what it doesn’t need through urine. That helps explain why taking a regular multivitamin rarely causes problems. Still, things can change if someone takes large doses for a long time. Some folks have reported mild stomach pain, nausea, or diarrhea after going overboard on supplements. That happened to me once, back in college, during an ambitious phase with various supplements; a queasy stomach and a few anxious hours became enough of a lesson.

Allergies to D-Calcium Pantothenate rarely pop up, but when they do, the symptoms show up as itching, rash, or swelling. This kind of reaction tends to be unique to the individual and not widespread. If someone already deals with allergies to other vitamins, it’s worth checking in with a healthcare professional before starting something new.

What Do Studies and Experts Say?

The National Institutes of Health notes very few risks in the range people usually take. Most studies suggest that reported side effects involve digestive issues and that the vitamin is generally well-tolerated. Toxicity seems nearly impossible through food, but taking massive doses (often more than 10 grams a day) ramps up the chances of stomach upset. That’s an amount no one would get from a normal diet or a standard multivitamin.

Healthcare providers tend to agree that D-Calcium Pantothenate is safe for most people, pointing out that side effects show up mainly after abuse or unusually high doses. I’ve never met a nutritionist who puts B5 at the top of their “watch list” for negative side effects. The focus falls far more often on fat-soluble vitamins or iron, where the risk of overdose feels more real.

Practical Tips for Safe Use

Anyone thinking of adding a supplement should take a close look at the label and check for unnecessary megadoses. My experience has taught me that more isn’t always better, especially if the supplement comes from unknown sources online. Chatting with a pharmacist or a registered dietitian can clear up whether a supplement fits well with current routines or medications.

Pay attention to any new or unusual digestive issues when starting a new supplement. It can help to keep a short note on what changes day-to-day. If severe discomfort, rashes, or trouble breathing show up, it’s smart to stop the supplement and call a doctor right away.

Balancing Benefits and Risks

For most healthy people, a balanced diet already brings in all the B5 needed—whole grains, eggs, meats, avocados, sweet potatoes, and peas cover the bases easily. Extra supplementation rarely tips the scales unless there’s a real medical reason. Knowing how your body reacts and keeping within the safe range helps turn something as ordinary as D-Calcium Pantothenate into just another tool for health, not a cause for concern.

What is the recommended dosage for D-Calcium Pantothenate?

Understanding D-Calcium Pantothenate

D-Calcium Pantothenate, known as the calcium salt of vitamin B5, plays a clear role in supporting the body’s metabolism and energy production. It helps break down fats, proteins, and carbohydrates, and has a history in clinical settings for treating pantothenic acid deficiency. Many people think about vitamins mainly when a doctor points them out, but B5 finds its way into plenty of supplements and multivitamins, so many already take it without paying much attention to the label.

Recommended Amounts for Adults and Kids

Most experts, including the National Institutes of Health, recommend 5 mg per day for adults. For children, amounts drop a bit: infants between 0.4 mg and 1.8 mg, young children about 2-4 mg, and teenagers climbing to 5 mg per day. Pregnant women look at about 6 mg, breastfeeding women at about 7 mg a day. These dosages aim to keep the body running well, ensuring proper metabolism and hormone synthesis.

From personal experience reading supplement bottles and looking into dietary guidelines, one big takeaway stands out: it’s rare to see people with severe vitamin B5 deficiency if they eat a balanced diet. Eggs, fish, chicken, whole grains, and mushrooms carry enough of this vitamin for most. Where it pops up as a health concern is in strict diets, malnutrition, or medical conditions causing digestive problems.

Too Much of a Good Thing?

It’s tempting to think more is always better, especially with vitamins marketed as “energy boosters.” But there’s a ceiling. Doses up to 1,000 mg per day have been studied, showing little harm, though large amounts sometimes lead to diarrhea or mild stomach upset. The body flushes out extra pantothenic acid through urine, so overdosing is rare, but that doesn’t turn mega-dosing into a healthy habit.

For most adults, more than 10 mg per day from supplements delivers no extra benefit. Based on research published by the Linus Pauling Institute and supported by clinical trial data, there’s no evidence high intake improves energy or stress resistance beyond normal levels. Chasing after huge dosages wastes money, and can distract from other habits—like improving sleep and regular exercise—that do far more for lasting energy.

Medical Uses vs. Everyday Needs

Doctors sometimes recommend higher doses for specific conditions, like treating dietary deficiencies or some skin disorders such as acne or wound healing. In these cases, professionals might direct up to 200 mg a day for short periods. This should always stay under medical supervision. Self-prescribing high doses isn’t wise—complex cases need lab tests and monitoring for side effects or interactions.

Reading Labels and Staying Informed

Anyone considering a new supplement should read labels carefully and check the daily value. Plenty of multivitamins already cover the recommended daily intake. Mixing different products can easily add up. Individual health needs and diet vary, so what suits one person may not suit another.

Better information about our own actual needs always beats following trends. Buy from companies with solid reputations and third-party testing. Run changes past a healthcare provider, especially for children, pregnant or breastfeeding women, or those with chronic illnesses.

Looking for Solutions for Deficiency

Nutrition professionals agree: a balanced diet covers vitamin B5 requirements for nearly everyone. If you worry about deficiency, check food variety first. For people with poor diets, chronic disease, or digestive conditions, taking a multivitamin fits the bill. Nutrition counseling and regular checkups help spot and deal with potential gaps before they become problems.

Is D-Calcium Pantothenate safe for pregnant or breastfeeding women?

Understanding D-Calcium Pantothenate

D-Calcium pantothenate, the calcium salt of vitamin B5, pops up on labels of prenatal supplements, fortified foods, and multivitamins. Its job is to help the body convert food into energy, while also supporting skin, hair, and digestive health. The human body can’t make vitamin B5, so everyone relies on food sources like eggs, meats, whole grains, and also on supplements when dietary intake drops.

Why Pregnant and Breastfeeding Women Ask About It

Pregnancy and nursing both put serious demands on a woman’s nutrients. Extra B vitamins support the healthy growth of a baby and replenish stores used up during breastfeeding. The question of safety with isolated compounds arises because not all supplements fit every person equally. Some nutrients cause harm in high doses, and not all synthetic forms get processed by the body in the same way as food-based versions.

What Research Tells Us

Most research points to D-calcium pantothenate being a safe, reliable form of vitamin B5 for most adults. The recommended daily amount of vitamin B5 in adults sits at about 5 mg, but pregnancy increases the need to 6 mg, and breastfeeding nudges the requirement up to 7 mg. Dietary surveys show that pregnant and lactating women usually get enough from what they eat. Supplementing often comes into play with those who lack a balanced diet or have specific medical needs.

The Food and Drug Administration classifies pantothenic acid as "generally recognized as safe" (GRAS) when used in foods, and prenatal supplements rarely exceed the daily need. A 2021 review in the journal Nutrients noted that toxicity from pantothenic acid is practically unheard of because the body flushes out the excess in urine. Too much B5 sometimes leads to mild digestive complaints, but these cases stem from very high, non-prescribed doses far above the amounts in standard prenatal vitamins.

Mixing Supplements with Real Food

Parents trying to decide about adding D-calcium pantothenate to their routine should remember most balanced diets already offer enough B5. Eggs, chicken, avocados, yogurt, and mushrooms carry solid amounts of pantothenic acid. Prenatal vitamins often include it for added security, but supplementing beyond that rarely gives extra benefit.

Issues pop up with mega-dosing. Studies show the body works best with a steady supply built from food, not high-dose pills. People who overuse supplements, hoping to boost energy or ward off hair loss, actually risk gut trouble—and get no added protection for baby or self.

Reliable Advice and Solutions

Women often juggle mixed messages, especially online. Smart choices start with guidance from healthcare providers, who look at a person’s history, diet, and overall health before recommending extra B vitamins. Blood tests sometimes highlight a real need for supplementation, particularly in cases of absorption disorders or some restrictive diets.

It’s tempting to seek reassurance in vitamin aisles, but good prenatal care focuses on whole food sources, evidence-supported supplements, and honest conversations about unique dietary needs. Every new parent deserves sound answers, not scare tactics or marketing promises. Pantothenic acid in reasonable doses stays firmly in the safe zone for most healthy pregnancies and while breastfeeding.

The Bottom Line for New Parents

Choosing a prenatal supplement, or deciding whether to add D-calcium pantothenate, should always revolve around actual needs, not myths or fear. The real power still lies in food, balanced habits, and honest medical advice. Parents holding that line wind up offering their child the best foundation for healthy growth.

D-Calcium Pantothenate
Names
Preferred IUPAC name Calcium (R)-2,4-dihydroxy-3,3-dimethylbutanamide-β-(pantoate)
Other names Calcium Pantothenate
Pantothenic acid calcium salt
Vitamin B5 calcium salt
Dexpanthenol calcium
Calcium D-pantothenate
Pronunciation /ˈdiː ˈkælsiəm pænˈθəneɪt/
Preferred IUPAC name Calcium 3-[(R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanoate
Other names Calcium pantothenate
Pantothenic acid calcium salt
Calcium D-pantothenate
Dexpanthenol calcium salt
Pronunciation /ˌdiːˈkælsiəm pænˈθəʊtəneɪt/
Identifiers
CAS Number 137-08-6
Beilstein Reference 1744265
ChEBI CHEBI:32597
ChEMBL CHEMBL1201201
ChemSpider 55553
DrugBank DB00361
ECHA InfoCard 100.029.270
EC Number 3.1.1.31
Gmelin Reference 82222
KEGG C00864
MeSH D009358
PubChem CID 86383
RTECS number S3X8634A6G
UNII 58H6RWO52I
UN number UN2811
CompTox Dashboard (EPA) CompTox Dashboard (EPA) of product 'D-Calcium Pantothenate' is "DTXSID0047038
CAS Number 137-08-6
Beilstein Reference 1496785
ChEBI CHEBI:31361
ChEMBL CHEMBL1201182
ChemSpider 5141
DrugBank DB00121
ECHA InfoCard 22b66a42-ec9e-4a11-9448-8f2a8c17069a
EC Number 200-638-8
Gmelin Reference 140198
KEGG C00864
MeSH D-Calcium Pantothenate
PubChem CID 8582
RTECS number BP4550000
UNII YG6R707N8R
UN number UN2811
CompTox Dashboard (EPA) DTXSID9020182
Properties
Chemical formula C18H32CaN2O10
Molar mass 476.53 g/mol
Appearance White crystalline powder
Odor Odorless
Density 0.6 g/cm3
Solubility in water Freely soluble in water
log P 0.01
Acidity (pKa) 8.69
Basicity (pKb) 11.2
Viscosity White or almost white powder
Dipole moment 2.98 D
Chemical formula C18H32CaN2O10
Molar mass 476.53 g/mol
Appearance White crystalline powder
Odor Odorless
Density 0.5 g/cm³
Solubility in water Freely soluble
log P -2.2
Vapor pressure Negligible
Acidity (pKa) 8.64
Basicity (pKb) 8.52
Viscosity White crystalline powder
Dipole moment 0 D
Thermochemistry
Std molar entropy (S⦵298) 674.96 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) −1647.6 kJ/mol
Std molar entropy (S⦵298) 576.6 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -1646.3 kJ/mol
Pharmacology
ATC code A11HA03
ATC code A11HA03
Hazards
Main hazards May cause eye, skin, and respiratory tract irritation.
GHS labelling GHS07; Warning; H319; Exclamation mark
Pictograms protect from sunlight", "keep dry", "store in a well-ventilated place", "hazardous to the aquatic environment
Signal word No signal word
Hazard statements Hazard statements: Not a hazardous substance or mixture according to the Globally Harmonized System (GHS).
Precautionary statements Precautionary statements: P264 Wash hands thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P330 Rinse mouth.
NFPA 704 (fire diamond) 1-1-0
Autoignition temperature 410 °C
Lethal dose or concentration LD50 Oral - rat - 10,000 mg/kg
LD50 (median dose) 10,000 mg/kg (rat, oral)
PEL (Permissible) 10 mg/m³
REL (Recommended) 4 mg
Main hazards May cause irritation to eyes, skin, and respiratory tract.
GHS labelling GHS07, Exclamation mark, Warning
Pictograms GHS07
Signal word No signal word
Precautionary statements Keep container tightly closed. Store in a cool, dry place. Avoid breathing dust. Use with adequate ventilation. Wash thoroughly after handling. Keep away from incompatible materials.
NFPA 704 (fire diamond) 1-0-0-0
Lethal dose or concentration LD50 (Oral, Rat): 10,000 mg/kg
LD50 (median dose) LD50 (oral, rat): 10,000 mg/kg
NIOSH SSS072W7HP
PEL (Permissible) PEL (Permissible Exposure Limit) for D-Calcium Pantothenate: "10 mg/m³ (total dust) as 8-hr TWA (OSHA)
REL (Recommended) Calcium Pantothenate (Vitamin B5) 10 mg
Related compounds
Related compounds Pantothenic acid
Calcium
Pantothenol
Dexpanthenol
Related compounds Pantothenic acid
Calcium
Vitamin B5
Pantothenol