Product Name: Creatine Monohydrate
Synonyms: Methylguanidoacetic acid monohydrate
Chemical Formula: C4H9N3O2·H2O
CAS Number: 6020-87-7
Intended Use: Nutritional supplement, laboratory chemical
Manufacturer: Manufacturer information and emergency contact provided on product packaging or accompanying paperwork.
GHS Classification: Not classified as hazardous according to GHS standards
Hazard Pictogram: No symbol
Risk: Overexposure may cause mild irritation to eyes, skin, or respiratory tract if dust is inhaled. Chronic effects not expected.
Precautionary Statement: Avoid inhaling dust, minimize direct contact with eyes and skin, use hygiene measures after handling, keep away from strong oxidizers and acids.
Chemical Identity: Creatine Monohydrate
CAS Number: 6020-87-7
EC Number: 200-306-6
Content: Greater than 99% pure
Impurities: No significant impurities expected from reputable suppliers.
Inhalation: Move to fresh air, support breathing as needed. Seek medical attention if symptoms persist.
Skin Contact: Remove contaminated clothing, rinse exposed area with soap and water. Consult medical care for irritation.
Eye Contact: Rinse cautiously with clean water for several minutes, remove contact lenses. If irritation continues, seek medical care.
Ingestion: Rinse mouth out with water. Slight stomach upset rarely occurs. Seek medical attention for large ingestions or persistent symptoms.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet on product bulk may cause dust
Hazardous Combustion Products: Nitrogen oxides, carbon oxides
Special Protective Gear for Firefighters: Self-contained breathing apparatus, full protective clothing
Firefighting Advice: Prevent run-off, cool containers with water spray.
Personal Precautions: Wear protective gloves, goggles, dust mask. Evacuate unnecessary personnel from area.
Spill Cleanup: Sweep up product carefully to avoid creating dust, place in labeled waste container. For large spills, ventilate area.
Disposal: See Disposal Considerations section. Wash spill area with plenty of water.
Handling: Minimize dust generation, avoid breathing dust, avoid direct contact with eyes and skin. Wash hands after handling, do not eat, drink, or smoke near processing areas.
Storage Conditions: Store in tightly closed original container, in a cool, dry, well-ventilated space. Keep away from food, incompatible chemicals, out of reach of children.
Other: Keep containers properly labeled, check for product integrity regularly.
Exposure Limits: Occupational exposure limits not established for this substance.
Engineering Controls: Adequate ventilation, use local exhaust during dusty operations.
Personal Protection: Safety goggles for eye protection, suitable gloves for hand protection, dust mask or respirator where dust exceeds nuisance concentration.
Hygiene Measures: Remove protective equipment before eating, wash thoroughly after handling, separately wash work clothing.
Appearance: White crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH (5% in water): 7.0
Melting Point: Decomposes before melting (around 292°C)
Boiling Point: Not applicable
Flash Point: Not applicable
Explosion Limits: Not expected to be explosive
Relative Density: Approximately 1.3 g/cm³
Solubility: Soluble in water (13.3 g/L at 20°C)
Partition Coefficient (log Kow): -2.1
Vapor Pressure: Negligible
Chemical Stability: Stable under standard storage and handling conditions.
Materials to Avoid: Strong oxidizing agents, strong acids, strong bases
Conditions to Avoid: Excess moisture, high temperatures
Hazardous Decomposition Products: Under combustion, releases carbon oxides, nitrogen oxides
Hazardous Reactions: No known hazardous polymerization.
Acute Toxicity: Oral LD50 in rats is estimated greater than 5000 mg/kg (low toxicity)
Skin Contact: No sensitization or severe irritation reported
Inhalation: Dust may irritate respiratory tract, coughing may occur from heavy exposure
Eye Contact: Mild irritation possible from contact
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity in studies using animal models relevant to human use.
Medical Conditions Aggravated: Individuals with previous respiratory conditions may notice slight discomfort from airborne dust, but no permanent effects expected.
Ecotoxicity: No acute aquatic toxicity observed at relevant concentrations (Daphnia, Algae, Fish: EC50/LC50 >100 mg/L)
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Expected to have low bioaccumulation (log Kow below zero)
Mobility in Soil: High mobility, dissolves easily in water
Other Adverse Effects: Not expected to disrupt aquatic or terrestrial organisms when used and disposed of appropriately.
Waste Handling: Collect all spilled or unused product. Dispose of in accordance with local, regional, and national regulations for non-hazardous chemical waste.
Method: Transfer to sealed, labeled container. In small amounts, dilute with water, flush to drain if permitted.
Do Not: Release undiluted material into sewers, surface water, or soil systems that drain to protected environments.
UN Number: Not regulated
Proper Shipping Name: Not regulated for transport
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not marine pollutant
Special Precautions: Protect packages from damage and moisture, ensure shipment is secure to prevent movement during transit.
Inventory Status: Listed on TSCA, EINECS, DSL, ENCS, AICS, and other major chemical inventories
Regulatory Status: Not classified as hazardous under GHS, OSHA, WHMIS, or EU REACH regulations
Labeling Requirements: Label as non-hazardous, note precaution to avoid dust inhalation, provide emergency contact information
Other Regulations: Complies with US Food and Drug Administration (FDA) regulations for use as a dietary supplement when purity criteria are met
Workplace Notification: SDS and product information available in work spaces as required by hazard communication programs.