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Material Safety Data Sheet: Cordycepin

Identification

Product Name: Cordycepin
Chemical Name: 3'-deoxyadenosine
Synonyms: Cordycepin, 3'-Deoxyadenosine
CAS Number: 73-03-0
Recommended Use: Laboratory chemical, pharmaceutical research
Supplier: Manufacturer or distributor details provided on official documentation
Emergency Number: Chemtrec or local poison control based on location

Hazard Identification

Classification: Not classified as hazardous under GHS regulations
Label Elements: No significant hazard pictogram required
Signal Word: Not applicable
Hazard Statements: May cause irritation to eyes, skin, and respiratory tract; effects stronger in individuals sensitive to nucleosides
Precautionary Statements: Avoid contact with skin and eyes; do not inhale dust; wear suitable protection; keep away from sources of ignition
Other Hazards: Not known to be explosive or reactive under typical laboratory conditions and handling

Composition / Information on Ingredients

Chemical Identity: Cordycepin
Common Name: 3'-Deoxyadenosine
CAS Number: 73-03-0
Concentration: ≥98% (Typical for lab-grade powder)
Impurities/Additives: Inert binders or stabilizers may be present in trace amounts based on supplier
Molecular Formula: C10H13N5O3
Molecular Weight: 251.24 g/mol

First Aid Measures

Eye Contact: Rinse eyes cautiously with water for several minutes; remove contact lenses if present and easy to do; seek medical attention if irritation develops
Skin Contact: Wash affected area with soap and water; remove contaminated clothing; obtain medical assistance if irritation occurs
Inhalation: Move to fresh air immediately; seek supportive medical care if respiratory symptoms occur
Ingestion: Rinse mouth thoroughly with water; seek prompt medical advice for any persistent symptoms or larger ingestions
Most Important Symptoms: Potential for local irritation; no known acute systemic toxicity in humans reported at lab exposure levels
Medical Attention: Physician should treat symptomatically and monitor for possible delayed reactions

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, carbon dioxide, or dry chemical extinguisher for fires involving organic powders
Unsuitable Media: Avoid direct water stream as it may scatter powder; do not use halogenated extinguishing agents unless necessary
Specific Hazards: Combustion may generate toxic vapors including nitrogen oxides and carbon monoxide
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective gear to handle potential inhalation of decomposition products
Firefighting Instructions: Move containers from fire area if safe; keep run-off water out of water supplies and sewers

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, lab coat or apron; avoid breathing dust or vapors
Environmental Precautions: Prevent entry into drains, waterways, or soil; contain spill using inert absorbent material
Methods for Cleanup: Sweep up carefully without creating dust; transfer to sealed bag or container for disposal; ventilate area after cleanup
Other Information: Wash spill site after material removal

Handling and Storage

Safe Handling Practices: Handle in well-ventilated area; avoid dust formation; use tools and techniques that minimize airborne powder
Hygiene Requirements: Wash hands after any handling; keep food and beverages away from work area; do not eat, drink, or smoke during use
Storage Conditions: Keep in tightly closed container; store in cool, dry, and well-ventilated location; protect from light and heat; keep away from incompatible chemical classes
Incompatible Materials: Oxidizing agents; strong acids or bases
Storage Life: Stable for up to two years if properly stored as described above

Exposure Controls and Personal Protection

Control Parameters: No established occupational exposure limits from OSHA, NIOSH, or ACGIH
Engineering Controls: Use local exhaust or fume hood to prevent airborne dust; keep workspace organized to avoid contamination
Personal Protective Equipment: Protective lab gloves (nitrile preferred), certified eye protection (safety glasses or goggles), lab coat, dust mask or respirator for high-concentration or prolonged exposures
Environmental Exposure Controls: Dispose of waste according to environmental regulations; report significant releases to local authorities if required

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Slight or odorless
pH: Not available in solid state
Melting Point: Approximately 227°C (decomposes on melting)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable under normal conditions
Solubility: Soluble in water (3-5 mg/ml typical); slightly soluble in ethanol and other solvents
Vapor Pressure: Not significant at room temperature
Relative Density: 1.66 g/cm³
Partition Coefficient (Log Kow): Data not available
Viscosity: Not relevant for solid powders
Decomposition Temperature: Above 230°C

Stability and Reactivity

Chemical Stability: Stable at standard temperature and pressure in sealed container
Reactive Properties: Not self-reactive or polymerizing; remains stable under recommended handling
Conditions to Avoid: Moisture, extreme heat, prolonged light exposure, strong oxidizing agents
Incompatible Materials: Strong bases, strong acids, oxidizing agents
Hazardous Decomposition: Fire or decomposition releases carbon monoxide, carbon dioxide, nitrogen oxides
Hazardous Polymerization: Does not occur under normal laboratory conditions

Toxicological Information

Possible Routes of Entry: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Limited data suggests low toxicity; oral LD50 (rat): not defined precisely, not acutely toxic at expected exposure levels
Chronic Effects: Long-term effects not fully established in humans; some studies show inhibition of cell growth in vitro
Possible Irritation: May cause mild to moderate irritation in contact with skin, eyes, or respiratory tract
Carcinogenicity: Not listed as a carcinogen by NTP, IARC, OSHA
Mutagenicity/Genotoxicity: Some evidence of DNA synthesis inhibition in laboratory cells
Target Organs: None known at low exposure typical of laboratory settings
Other Information: Use caution until further toxicological data becomes available

Ecological Information

Aquatic Toxicity: No specific data; care should be taken to prevent large-scale spills into waterways as potential effects on aquatic organisms are unknown
Persistence and Degradability: No comprehensive data; expected to degrade slowly in environment by microbial activity
Bioaccumulation Potential: Not anticipated based on molecular structure and expected metabolism
Mobility in Soil: Limited mobility predicted due to solubility profile; data lacking
Other Adverse Effects: Laboratory handling unlikely to produce environmental risk where proper waste management is practiced

Disposal Considerations

Waste Disposal Methods: Place in sealed container; hand over to authorized hazardous waste disposal facility; avoid direct release into sewer or natural streams
Contaminated Packaging: Dispose of as hazardous chemical waste
Special Precautions: Small quantities can go with laboratory chemical waste if allowed by local authority; documentation follows generator's responsibility
Relevant Regulations: Follow national, state, and local rules for chemical waste

Transport Information

UN Number: Not listed as dangerous goods for transport under UN/IMDG/ICAO rules
Transport Hazard Class: Non-hazardous as per known shipment history
Packing Group: Not applicable
Environmental Hazards: Avoid uncontrolled release
Special Transport Precautions: Carry in well-sealed, labeled packaging; protect from damage and moisture during transit

Regulatory Information

Labelling Requirements: No special hazard label needed at standard laboratory concentrations
Inventory Status: Listed or exempted in TSCA, REACH, EINECS, DSL (check supplier/compliance updates for changes)
OSHA Hazards: Not classified as hazardous chemical
SARA/Title III: No components present at or above threshold reporting levels
Other Federal/State Regulations: Not subject to specific control but standard laboratory chemical requirements apply
International Regulations: Handle as laboratory chemical; national and regional chemical safety laws apply
Workplace Notification: Safety training for users, SDS accessible to all handlers, routine review of safe handling practices