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Product Name: Conjugated Linoleic Acid
Chemical Name: Octadecadienoic acid, conjugated
Synonyms: CLA
CAS Number: 2420-56-6
Recommended Uses: Dietary supplement, food additive, research chemical
Supplier Details: Manufacturer’s info, phone number for emergencies and routine questions
Emergency Contact: 24-hour support line provided by the supplier or Chemtrec
GHS Classification: Not classified as hazardous according to OSHA Hazard Communication Standard
Hazard Statements: Low hazard under normal use, may irritate eyes and skin if contact persists
Signal Word: None required for current classifications
Precautionary Statements: Avoid strong inhalation of spray or dust, use only with proper ventilation, prevent contact with eyes and prolonged skin contact
Potential Health Effects: Eye discomfort, mild skin irritation, risk of mild gastrointestinal upset if ingested in large amounts
Label Elements: No pictogram obligatory, basic workplace hygiene recommended
Chemical Name: Conjugated Linoleic Acid (CLA)
Common Forms: Mixture of cis-9, trans-11, and trans-10, cis-12 isomers
Concentration: 80-95% pure fatty acid isomers depending on source
Impurities: Residual carrier oil, minor triglycerides below safety risk thresholds
Additives: None required for pure chemical; may appear with tocopherols as antioxidants in consumer formulations
Eye Contact: Rinse gently with water for at least 15 minutes, remove contact lenses if present, seek medical advice if irritation persists
Skin Contact: Wash with mild soap and water, remove contaminated clothing, seek medical attention for persistent redness or discomfort
Inhalation: Remove to fresh air, keep calm, consult physician if symptoms develop
Ingestion: Rinse mouth with water, call a doctor in case of adverse reaction or large intake
Important Note: No known acute toxicity requiring emergency intervention under standard occupational settings
Suitable Extinguishing Media: Dry chemical, foam, CO2, sand
Unsuitable Media: Direct water jet can spread burning oil
Special Hazards: Combustion can release fumes, smoke, carbon monoxide and carbon dioxide
Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus recommended
Advice: Cool fire-exposed containers with water spray, prevent runoff to drains or watercourses
Personal Precautions: Avoid direct contact with liquid, use gloves and eye protection, ensure adequate ventilation
Environmental Precautions: Keep out of surface water, sewers and soil, inform authorities if significant spill escapes into environment
Methods for Cleanup: Absorb with sand or inert absorbent material, collect in appropriate container for disposal, wash area with water and detergent
Handling Spills: Remove ignition sources, wear proper protective gear, ventilate area, prevent slipping risk from oil residue
Handling: Wear standard laboratory gloves and eye protection, work in ventilated area, use non-sparking tools
Storage: Store in tightly sealed containers, keep in cool (15-25°C), dry place away from direct sunlight, separate from oxidizers and other incompatible substances
Hygiene Measures: Wash hands after use, avoid eating, drinking, or smoking around the substance, keep out of reach of children
Storage Containers: Use food-grade, well-sealed glass or plastic vessels without metal contamination
Workplace Exposure Limits: None established by OSHA, ACGIH, or NIOSH
Engineering Controls: General mechanical ventilation recommended for bulk handling
Personal Protective Equipment: Nitrile gloves, safety goggles, protective clothing
Respiratory Protection: Not typically required except during high-dust or aerosol generation
Hygiene: Wash hands and exposed skin after handling, avoid cross-contamination in eating or break areas
Appearance: Pale yellow to amber oily liquid
Odor: Mild, fatty, characteristic
Melting Point: About -5 to 10°C depending on purity and isomer ratio
Boiling Point: Decomposes before boiling, vapors not expected under normal handling
Solubility: Insoluble in water, soluble in most organic solvents and vegetable oils
Density: 0.90–0.94 g/cm³ at 20°C
Flash Point: above 150°C (open cup test)
Viscosity: More viscous than water, flows easily at room temperature
Partition Coefficient: log P between 6 and 8 (highly lipophilic)
Chemical Stability: Stable under recommended storage, avoid prolonged heat exposure
Possible Reactions: May oxidize forming peroxides or aldehydes under extreme heat or sunlight
Incompatible Materials: Strong oxidizers (e.g., hydrogen peroxide, chlorates)
Hazardous Decomposition Products: Smoke, carbon dioxide, traces of acrolein and other unsaturated aldehydes
Special Precautions: Protect from heat, strong bases, acids, and light to maintain shelf life
Routes of Exposure: Eyes, skin, ingestion, inhalation (aerosol, powder)
Acute Toxicity: Oral LD50 (rat) > 5,000 mg/kg, considered non-toxic at typical exposures
Chronic Effects: No evidence for carcinogenicity or reproductive toxicity at relevant doses
Irritation: Mildly irritating to eyes and skin on prolonged contact
Sensitization: Not widely reported, rare in clinical experience
Additional Information: High concentrations may cause gastrointestinal upset, excessive intake from supplements not recommended for children or pregnant women without medical supervision
Aquatic Toxicity: Low toxicity to aquatic organisms based on current data
Persistence and Degradability: Biodegradable, breaks down through oxidation and microbial action
Bioaccumulation: Low potential for bioaccumulation given natural fatty acid metabolism in most ecosystems
Mobility: Not very mobile in soil; binds to organic matter
Other Hazards: Large spills may form films on water surfaces causing oxygen transfer problems; environmental impact considered low with proper usage and disposal practices
Waste Handling: Dispose in accordance with local, regional and national regulations for food-grade chemicals
Method: Small quantities may be washed away with copious amounts of water and soap
Recycling: Not typically recycled, consult waste management provider
Contaminated Packaging: Rinse thoroughly or incinerate under controlled conditions
Precautions: Do not pour directly into drains, watercourses or natural environment in undiluted form
UN Number: Not regulated
Proper Shipping Name: Not restricted as dangerous goods
Transport Hazard Class: Not subject to classification, not flammable or reactive under routine transport
Packing Group: Not applicable
Special Precautions: Seal containers tightly, protect against physical damage, store upright in secondary containment
US Regulations: Not subject to TSCA restrictions for food-grade ingredient, FDA allows use in food supplements, GRAS status in many applications
EU Regulations: Meets European Food Safety Authority requirements for supplements and certain foods
Labeling Obligations: No special hazard labeling required; workplace labeling should cover routine health hygiene
Other International Regulations: Subject to national requirements for food additives and dietary supplement ingredients
Chemical Inventory Status: Listed in major inventories including EINECS, DSL, AICS
Worker Safety: Follows standard occupational health standards for food contact and cosmetic ingredient use in accordance with local laws
