© 2026 Alchemist Worldwide Ltd,
All Right Reserved
Product Name: Chromium Nicotinate
Synonyms: Chromium(III) nicotinate, Chromium trinicotinate
Chemical Formula: C18H12CrN3O6
CAS Number: 64452-96-6
Recommended Use: Nutritional supplement ingredient, laboratory use
Manufacturer Identification: Producer name and address available on request from supplier, contact for full emergency response.
Emergency Phone Number: Local Poison Control Center or 911 in case of medical emergencies.
GHS Classification: Acute toxicity, Oral (Category 4); Eye irritation (Category 2A); Skin irritation (Category 2)
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes eye and skin irritation; possible respiratory irritation upon inhalation of dust.
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; wear appropriate protective gloves and eye protection.
Hazard Symbol: Exclamation mark
Chemical Name: Chromium(III) Nicotinate
Common Names: Chromium nicotinate, Chromium trinicotinate
Concentration: 97–100% by weight
Impurities: Trace levels of unbound nicotinic acid, water, or mixed chromium salts (typical for industrial production)
Other Information: No additional hazardous components present above 1%
Inhalation: Move person to fresh air, seek medical attention if irritation or discomfort persists.
Skin Contact: Remove contaminated clothing, wash with soap and water. If redness or irritation continues, get medical advice.
Eye Contact: Flush eyes with plenty of water for at least 15 minutes, hold eyelids apart. Call a doctor if discomfort lingers.
Ingestion: Rinse mouth with water if person is conscious, do not induce vomiting. Get medical help immediately for large amounts.
Symptoms: Irritation to eyes, skin, mucous membranes; possible stomach discomfort if swallowed.
Suitable Extinguishing Media: Use dry chemical, foam, water spray, or carbon dioxide.
Special Hazards: Product may decompose under fire conditions to release toxic fumes including chromium oxides, nitrogen oxides.
Protective Equipment: Firefighters require self-contained breathing apparatus, full protective clothing.
Fire and Explosion Hazards: Powder form may increase dust explosion risk in confined spaces.
Personal Precautions: Wear suitable gloves, safety goggles, dust mask or respirator, avoid contact with skin or inhaling dust.
Environmental Precautions: Keep spills out of sewers or waterways; prevent from entering soil or surface water.
Cleanup Methods: Sweep or vacuum material using tools that minimize dust generation, place waste in labeled container for disposal.
Disposal: Clean area with water and detergent after bulk is picked up, avoid raising dust during cleanup.
Handling: Use in ventilated areas, avoid contact with skin, eyes, and clothing. Avoid creating or inhaling dust. Cleaning hands after use is important.
Storage Conditions: Store in cool, dry, well-ventilated spot, keep container tightly closed. Protect from direct sunlight, humidity, and incompatible materials like strong acids and oxidizers.
Special Considerations: Avoid storage next to food, drinks, or animal feed; label containers clearly.
Exposure Limits: No established OSHA or ACGIH exposure limit for this compound, but chromium(III) compounds have limits of 0.5 mg/m3 TWA (OSHA).
Engineering Controls: Ensure adequate local exhaust or general ventilation at workplace.
Personal Protection: Wear approved respiratory protection if risk of dust inhalation, safety goggles, nitrile or latex gloves, and protective lab coat or clothing.
Hygiene Measures: Wash hands, face, and contaminated skin thoroughly after handling. Remove contaminated clothing and wash before reuse.
Appearance: Fine violet or dark purple powdered solid
Odor: Odorless
Melting Point: Not well defined, decomposes above 200°C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Slightly soluble in water, more soluble in acidic solutions
Density: About 1.7 g/cm3
pH (solution): Slightly acidic to neutral (5–7)
Other Properties: Decomposes in strong acids and oxidizing environments; stable under recommended handling.
Stability: Chemically stable under standard storage and handling conditions, away from incompatible substances.
Reactivity: Not reactive under normal handling; reacts with strong acids, oxidizing agents.
Decomposition Products: Chromium oxides, nitrogen oxides, carbon oxides may be released on burning or decomposition.
Polymerization: Does not undergo hazardous polymerization.
Acute Toxicity: Mildly harmful if swallowed; oral LD50 in rodents above 2000 mg/kg.
Chronic Effects: Continuous exposure to high doses can affect liver, kidneys, with symptoms like nausea and diarrhea noted in some human supplementation studies.
Skin/Eye Irritation: Dust can cause irritation.
Sensitization: Not known to cause allergic reactions, though chromium salts sometimes sensitize sensitive individuals.
Carcinogenicity: Chromium(III) (unlike chromium(VI)) is not listed as a carcinogen by IARC, NTP, or OSHA.
Aquatic Toxicity: Chromium(III) salts may be moderately toxic to aquatic organisms when released in quantity.
Persistence and Degradability: Chromium in this state binds tightly to soils, tends to accumulate in sediment.
Bioaccumulation: Likelihood is low for bioaccumulation.
Mobility in Soil: Low mobility; compound tends to be immobile in soil, limiting groundwater risk, but spills on soil still require cleanup.
Other Adverse Effects: Large or repeated releases can be harmful to aquatic life.
Waste Treatment: Place solid waste in tightly sealed containers, handle as hazardous chemical waste according to local, state or federal regulations.
Contaminated Packaging: Rinse thoroughly, recycle or dispose of as hazardous waste as governed by authority rules.
Special Instructions: Avoid flushing in large quantities to sewer or waterways. Cleanup operators wear protective equipment, minimize dust.
UN Number: Not regulated for transport by USDOT, IMDG or IATA for small quantities.
Proper Shipping Name: Not hazardous for air, sea, or road shipments in recognized packaging.
Transport Hazard Class: Not classified as dangerous goods.
Packing Group: Not assigned.
Special Precautions: Package securely, prevent damage or leakage, follow local rules for chemical transportation.
OSHA Status: Not specifically regulated as a hazardous substance, broadly covered under general chemical safety standards.
TSCA: Listed in the TSCA inventory of chemicals.
SARA Title III: Not listed as an extremely hazardous substance.
California Prop 65: Not subject to Proposition 65 requirements as chromium(III) is not listed.
Other Regulatory Info: Complies with EU REACH regulations for imported and manufactured substances, review local guidelines for specifics.
