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Product Name: Chlortetracycline Hydrochloride
Chemical Formula: C22H23ClN2O8·HCl
Synonyms: Aureomycin hydrochloride
CAS Number: 64-72-2
Recommended Use: Veterinary antibiotic, research chemical
Supplier: Pharmaceutical or chemical provider information available on request
Contact Email/Phone: Supplier emergency number, local emergency services
Emergency Overview: Yellow, odorless, crystalline powder for laboratory and veterinary settings
GHS Classification: Acute toxicity (oral, category 4); Eye irritation (category 2A); Specific target organ toxicity - repeated exposure (category 2)
Pictograms: Exclamation mark, Health hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes serious eye irritation; may cause damage to organs through prolonged or repeated exposure
Route of Entry: Inhalation, skin contact, ingestion, eye contact
Potential Health Effects: Allergic reactions, gastrointestinal disturbances, dermal/respiratory sensitization
Chemical Name: Chlortetracycline Hydrochloride
Concentration: >98%
Impurities: May include related tetracycline compounds & residual solvents in trace amounts
Other Ingredients: None reported as hazardous
Eye Contact: Rinse eyes with water for several minutes lifting upper and lower eyelids; remove contact lenses if present and easy to do; seek medical attention
Skin Contact: Remove contaminated clothing; wash skin with soap and water
Inhalation: Move to fresh air; assist breathing if necessary; seek medical attention if symptoms arise
Ingestion: Rinse mouth; do not induce vomiting; seek medical attention immediately
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Strong water jets
Hazardous Combustion Products: Carbon oxides, nitrogen oxides, hydrochloric acid, chlorine compounds
Protective Equipment: Full protective gear and self-contained breathing apparatus required
Special Procedures: Avoid smoke inhalation; cool exposed containers with water spray
Personal Precautions: Use personal protective equipment; prevent skin and eye contact
Environmental Precautions: Avoid entry into drains, waterways, and soil
Clean-Up Methods: Sweep or scoop up spilled product; avoid dust generation; place in suitable, labeled container for disposal
Reference to other sections: Use advice on safe handling and disposal procedures
Handling: Use in well-ventilated areas; avoid contact with skin, eyes, and clothing; do not breathe dust
Storage: Keep tightly closed in original container; store in cool, dry, and well-ventilated location; protect from light and moisture
Incompatibilities: Strong oxidizing agents, acids, alkalis
Hygiene Advice: Wash hands after handling; do not eat, drink, or smoke in the work area
Exposure Limits: No occupational exposure limits established for this material
Engineering Controls: Local exhaust ventilation recommended
Personal Protective Equipment: Safety goggles or face shield; chemical-resistant gloves (nitrile or neoprene); lab coat or coveralls; respiratory protection if dust generated
Environmental Controls: Prevent spillage or leakage; use containment for process areas
Appearance: Yellow crystalline powder
Odor: Odorless
pH: Approximately 2.0–3.0 (1% solution)
Melting Point: 210–220°C (decomposition)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Soluble in water; slightly soluble in ethanol
Vapor Pressure: Not available
Density: ~1.7 g/cm³
Partition Coefficient (n-octanol/water): Not available
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under normal use and storage
Conditions to Avoid: Excess heat, light, and moisture
Incompatible Materials: Strong oxidizers, reducing agents, strong acids and bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, chlorine compounds, nitrogen oxides
Acute Toxicity: LD50 (oral, rat): 4,600 mg/kg
Potential Health Effects: May cause irritation to eyes, skin, and respiratory tract; large doses may affect liver, kidneys, and bone marrow
Chronic Effects: May cause allergic responses including dermatitis, asthma, or photosensitivity
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: Adverse effects reported in animal tests, but relevance to humans is unclear
Sensitization: Skin and respiratory sensitization possible with repeated exposure
Aquatic Toxicity: Toxic to aquatic life with long lasting effects; LC50 values available for some fish species show significant risk in case of large spill
Persistence and Degradability: May persist in the environment due to stability against biodegradation
Bioaccumulative Potential: Low potential for bioaccumulation expected
Mobility in Soil: Mobile in water, particularly in lower pH environments
Other Adverse Effects: Disruption to microbial communities possible with contamination of water bodies
Waste Treatment Methods: Dispose of in accordance with national, regional, local regulations; incineration preferred in controlled facility
Product Disposal: Do not discharge into drains or environment; collect and transfer to licensed waste disposal contractor
Packaging Disposal: Empty containers may retain residues; treat packaging as hazardous unless decontaminated by specialist methods
UN Number: Not regulated for transportation
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class(es): Not hazardous for transport
Packing Group: Not assigned
Environmental Hazards: Avoid large release into environment during transport
Special Precautions for User: Avoid contact with skin and eyes; use sealed packaging
TSCA Status: Not listed as a regulated chemical under TSCA
REACH Status: Subject to registration or restrictions in the EU
OSHA Status: Not regulated as a hazardous chemical
WHMIS Classification (Canada): Not classified as a controlled product
Other Regulatory Listings: Subject to pharmaceutical controls in many regions; monitor national legislation for veterinary or feed-use restrictions
