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Product Name: Cellulase
Synonyms: Cellulose enzyme, EC 3.2.1.4
Chemical Formula: Protein complex
CAS Number: 9012-54-8
Recommended Use: Enzyme for industrial, laboratory, or research application
Supplier Information: Manufacturer or distributor contact, emergency phone number, address provided by your source
Emergency Contact: Regional Poison Control or Chemtrec
GHS Classification: Respiratory sensitizer, Skin sensitizer
Signal Word: Warning
Hazard Statements: May cause allergy or asthma symptoms or breathing difficulties if inhaled; may cause allergic skin reaction
Pictograms: Exclamation mark, health hazard
Precautionary Statements: Avoid inhalation, use protective equipment, wash thoroughly after handling, avoid release to environment
Routes of Exposure: Inhalation, skin contact, eye contact
Potential Health Effects: Shortness of breath, rash, itchy or irritated skin, red or watery eyes, respiratory discomfort
Main Ingredient: Cellulase enzyme from Aspergillus niger or Trichoderma reesei
Enzyme Protein Content: Variable; ranges from 10% to 90% w/w depending on formulation
Fillers and Carriers: Starch, dextrin, maltodextrin, or sodium chloride depending on grade
Other Components: Trace fermentation by-products, moisture, stabilizers
Impurities: Trace fungal biomass, protein fragments
Mixture or Single Substance: Enzyme preparation as a complex mixture
Inhalation: Move person to fresh air, seek medical attention if respiratory symptoms persist
Skin Contact: Wash area thoroughly with soap and water, remove contaminated clothing
Eye Contact: Rinse carefully with plenty of water for 10 minutes, consult medical help if irritation remains
Ingestion: Rinse mouth with water, drink water for dilution, medical guidance if symptoms develop
Advice to Physician: Symptomatic and supportive care with monitoring for allergic reaction
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: None identified for the enzyme itself
Special Protective Equipment: Self-contained breathing apparatus, protective clothing to avoid inhalation of dust or fumes
Fire and Explosion Hazards: Fine dust may form explosive mixture with air; combustion releases carbon oxides, nitrogen oxides
Hazardous Combustion Products: Carbon dioxide, carbon monoxide, low levels of nitrogen oxides, potential acrid smoke
Protective Actions: Isolate area, remove containers from exposure, remain upwind
Personal Precautions: Wear respiratory protection, avoid dust generation
Environmental Precautions: Prevent runoff into drains, surface water, or soil
Containment: Collect spilled substance using dry methods, dampen to prevent dust
Cleanup: Vacuum or sweep up without creating dust, bag for disposal
Decontamination: Use water to clean area after removal, ventilate affected zone
Waste Disposal: Dispose according to regional, national, local environmental regulations
Precautions for Safe Handling: Minimize dust, avoid inhalation and skin contact, use adequate ventilation
Hygiene Measures: Wash hands after handling, remove contaminated clothing before eating or drinking
Conditions for Safe Storage: Store in cool, dry, well-ventilated place, sealed original container
Incompatible Materials: Strong oxidizers, acids or bases may degrade enzyme
Storage Temperature: Below 25°C to maintain activity
Packaging Materials: Compatible with plastic, glass, stainless steel
Engineering Controls: Local exhaust ventilation or enclosure of process to control dust
Respiratory Protection: NIOSH-approved particulate respirator (N95 or P100 mask)
Skin Protection: Chemical-resistant gloves
Eye Protection: Safety goggles or face shield
Personal Hygiene: Avoid touching face, nose, mouth with contaminated hands
Monitoring: Workplace air monitoring for dust exposure
Occupational Exposure Limits: No established limit for cellulase; best practice suggests reducing exposure to lowest feasible level
Appearance: Fine powder or granules, white to light brown
Odor: Faint, characteristic fermentation scent
pH (1% solution): 4.5 – 7.5
Melting Point: Not applicable as product decomposes
Boiling Point: Not applicable
Flash Point: Not flammable as a solid
Solubility: Readily disperses in water forming turbid suspension
Vapor Pressure: Not volatile
Density: Typically 0.4 – 0.7 g/cm³
Stability: Sensitive to moisture and heat
Partition Coefficient: Not applicable
Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactions under normal use
Conditions to Avoid: Heat, moisture, exposure to air, sunlight
Incompatible Materials: Strong oxidizers, acids, bases can denature enzyme
Hazardous Decomposition: Thermal decomposition may release nitrogen oxides, carbon oxides
Polymerization: Will not occur
Acute Toxicity: Not acutely toxic, large amounts may irritate mucous membranes
Skin Sensitization: Some users may develop allergic reaction with prolonged exposure
Respiratory Sensitization: Inhalation can trigger asthma-like symptoms and long-term sensitivity
Chronic Effects: Repeated exposure can cause occupational asthma or dermatitis
Carcinogenicity: Cellulase not classified as carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity: No evidence of mutagenicity from available studies
Other Health Effects: High dust concentrations may aggravate preexisting lung conditions
Ecotoxicity: Cellulase is biodegradable and not expected to persist or bioaccumulate
Aquatic Toxicity: No acute effects on aquatic species at environmental concentrations
Soil Mobility: Rapid breakdown through microbial activity
Persistence and Degradation: Readily degraded by natural processes
Bioaccumulation Potential: Very low
Other Effects: Large spills may cause local oxygen depletion during degradation
Recommended Disposal Methods: Dispose in landfill or by incineration in accordance with local laws
Contaminated Packaging: Rinse containers; offer recycling where possible
Sewage Disposal: Small quantities diluted with water can be flushed down drain if permitted
Special Considerations: Avoid release of large amounts into surface water or soil
UN Number: Not regulated as hazardous for transport
Proper Shipping Name: Cellulase, enzyme preparation
Transport Hazard Class: Not classified
Packing Group: Not applicable
Labeling Requirements: No special requirement
Transport Precautions: Protect from moisture and excessive heat during transit
Environmental Hazards: Not a marine pollutant
Special Transport Notes: Use sealed packaging to minimize dust release
Safety, Health, and Environmental Regulations: Cellulase generally not listed as hazardous under major global regulations (OSHA, EU, WHMIS, GHS)
Inventory Listings: Listed on TSCA, DSL, EINECS/ELINCS
Other Regulations: If formulated with other hazardous chemicals, those components may attract separate regulation
Workplace Labelling: Label workplace containers as per hazard identification section
Consumer Use Restrictions: Not intended for pharmaceutical or consumer use without additional guidance
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
