© 2026 Alchemist Worldwide Ltd,
All Right Reserved
Product Name: Cefotaxime
Chemical Name: (6R,7R)-7-([2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-acetoxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS Number: 63527-52-6
Synonyms: Claforan, Cephalosporin C
Recommended Use: Pharmaceutical antibiotic, research and laboratory use
Manufacturer Information: [Manufacturer info as listed on label or certificate]
Classification: Not classified as hazardous according to OSHA Hazard Communication Standard (29 CFR 1910.1200)
Potential Health Effects: May cause allergic skin or respiratory reactions, possible gastrointestinal upset, risk of sensitization for those with pre-existing allergies
Signal Word: Warning
Hazard Statements: May cause allergic reaction
Precautionary Statements: Avoid contact with eyes, skin, and clothing; avoid breathing dust; use in well-ventilated areas
GHS Label Elements: Irritant symbol
Other Hazards: Potential hazard by inhalation of powder, risk during prolonged handling for sensitive individuals
Cefotaxime Sodium: 100%
Impurities: Trace levels consistent with pharmaceutical manufacturing
Molecular Formula: C16H17N5NaO7S2
Molecular Weight: 477.46 g/mol
Purity: Pharmaceutical grade as documented on certificate of analysis
Inhalation: Remove to fresh air, seek medical advice if symptoms occur
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, seek medical attention if irritation develops
Eye Contact: Rinse cautiously with water for at least 15 minutes, hold eyelids open, seek prompt medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, obtain medical attention if you feel unwell
Most Important Symptoms: Allergic reaction such as rash, throat swelling, breathing difficulty, gastrointestinal upset
Suitable Extinguishing Media: Use water spray, dry chemical powder, carbon dioxide, foam
Unsuitable Extinguishing Media: High-pressure water streams
Specific Fire Hazards: May emit toxic fumes of nitrogen oxides, sulfur oxides, and carbon oxides under fire conditions
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Other Precautions: Avoid inhaling combustion products, evacuate unnecessary personnel from area, contain runoff to prevent environmental contamination
Personal Precautions: Use personal protective equipment such as gloves, goggles, and masks, avoid generating dust
Environmental Precautions: Prevent uncontrolled release to the environment, avoid discharge into sewers or drains
Methods for Cleanup: Sweep or vacuum material into suitable labeled containers, avoid raising dust, wash spill area with water and detergent
Reference to Other Sections: Refer to disposal considerations and exposure controls for safe handling
Handling: Use in a chemical fume hood for bulk manipulation, avoid inhalation and contact with skin or eyes, do not eat or drink in work area, observe good industrial hygiene
Storage: Keep containers tightly closed in a cool, dry, and well-ventilated location, protect from moisture and direct sunlight, store away from incompatible materials such as oxidizing agents, maintain refrigerator or freezer storage for long-term stability where recommended by manufacturer
Occupational Exposure Limits: No OSHA or ACGIH exposure limits established specifically for cefotaxime
Engineering Controls: Local exhaust ventilation or chemical fume hood recommended to minimize exposure
Personal Protective Equipment: Nitrile or latex gloves, safety goggles, laboratory coat, particulate respirator for powder manipulation
Hygiene Measures: Wash hands thoroughly after handling, change contaminated clothing, avoid hand-to-mouth or skin contact
Appearance: White to off-white crystalline powder
Odor: Odorless
pH: 4.5 to 6.5 in aqueous solution
Boiling Point: Data not available
Melting Point: 161-166°C
Solubility: Freely soluble in water, slightly soluble in methanol, insoluble in acetone and chloroform
Vapor Pressure: Not applicable (non-volatile solid)
Flash Point: Not applicable
Partition Coefficient: Log Kow -2.27 (estimated)
Viscosity: Not applicable
Decomposition Temperature: Above 185°C (thermal decomposition releases toxic gases)
Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: Exposure to moisture, heat, direct light, incompatible substances
Incompatible Materials: Strong oxidizing agents, strong acids and bases
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon oxides
Hazardous Reactions: No dangerous reactions known under normal use
Acute Toxicity: Oral LD50 (rat): >5000 mg/kg (estimated)
Skin Corrosion/Irritation: No significant skin irritation expected, risk of sensitization after repeated contact
Serious Eye Damage/Irritation: May cause mild irritation
Respiratory or Skin Sensitization: Sensitizer for susceptible individuals
Carcinogenicity: Not reported as carcinogenic by IARC, NTP, OSHA
Reproductive Toxicity: No human data available, animal studies suggest low reproductive hazard
Specific Target Organ Toxicity: None identified with short-term exposure
Eco-toxicity: May be harmful to aquatic organisms in significant concentrations
Persistence and Degradability: Not readily biodegradable in environment, some breakdown in sewage treatment
Bioaccumulative Potential: Low, based on physico-chemical properties
Mobility in Soil: Likely to be mobile, water-soluble
Other Adverse Effects: Antibiotics may disrupt microbial activity in wastewater or natural systems; careful management necessary to minimize release
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations for pharmaceutical waste
Product Disposal: Incinerate or dispose of with approved hazardous waste contractor; do not discharge unused material to drains or surface water
Container Disposal: Triple rinse containers, destroy by incineration or send to licensed landfill
Precautions: Avoid direct contact, prevent spread of dust or residue, document all disposals to support regulatory compliance
UN Number: Not regulated for transport
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Non-hazardous
Packing Group: Not applicable
Special Precautions: Ensure packaging is intact and labeled, prevent movement of containers during transit, maintain records of batch and quantity
Environmental Hazards: Not classified as marine pollutant
US Federal Regulations: Not listed under SARA Title III Sections 302/304/311/312/313, not subject to TSCA inventory for drug applications
EU Regulations: Not classified for supply under EC Directives; subject to regulation as a medicinal product
Other Regulatory Lists: Complies with relevant pharmacopeial standards, labeled for research or prescription use per FDA or EMA standards
Workplace Safety: Employers required to provide training and make MSDS available under OSHA Hazard Communication Standard
Other Information: Product intended for use by qualified personnel only, keep out of reach of unauthorized users
