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Product Name: Casein Phosphopeptide
Chemical Name: Casein Phosphopeptide
Synonyms: CPP, Milk-derived Casein Peptide
Recommended Use: Nutritional supplement, ingredient in functional foods, pharmaceuticals, dental care products
Manufacturer: See product label
Emergency Phone: Refer to local regulations
CAS Number: 9000-71-9
EC Number: Not assigned
Molecular Formula: Complex peptide mixture from milk casein hydrolysate
GHS Classification: Substance is not classified as hazardous according to GHS
Physical State: Fine powder or granule
Color: Off-white to pale yellow
Odor: Faint, characteristic, similar to milk
Potential Health Effects: May cause slight irritation to sensitive individuals by inhalation, ingestion, or contact with eyes. Allergic reactions possible for milk-allergic users.
Label Elements: No symbol required
Precautionary Statements: Avoid dust generation, use hygiene practices, prevent contact with eyes and prolonged inhalation.
Chemical Composition: Peptides and phosphopeptides derived from casein (milk protein)
Main Component: Casein phosphopeptides (>90%)
Minor Components: Traces of lactose, minerals (calcium, phosphorus), residual amino acids
Impurities: None of toxicological significance
Ingredient Source: Milk (bovine origin)
Protein Purity: Typically above 90% by weight
General Advice: Move affected person away from exposure; seek medical attention if symptoms persist
Inhalation: Move to fresh air, rinse mouth, provide water to drink, consult medical help if prolonged discomfort occurs
Skin Contact: Wash thoroughly with mild soap and water, remove contaminated clothing
Eye Contact: Rinse cautiously with water for at least 10–15 minutes, remove contact lenses if present and easy to do, seek medical advice if irritation persists
Ingestion: Rinse mouth, give water to drink, do not induce vomiting, get medical attention if any discomfort
Note for Physicians: Treat symptomatically and provide supportive care as required
Suitable Extinguishing Media: Water spray, foam, carbon dioxide (CO2), dry chemical powder
Unsuitable Extinguishing Media: None known
Specific Hazards: May produce hazardous decomposition products such as carbon oxides, nitrogen oxides when burned
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Explosion Risk: Dust can form explosive mixtures with air in the presence of ignition sources
Fire-Fighting Procedures: Isolate area, control dust, cool containers with water, prevent firewater runoff from contaminating drains
Personal Precautions: Wear suitable protective equipment including mask, gloves, goggles
Environmental Precautions: Prevent large spills from entering watercourses or sewers
Containment Methods: Prevent further leakage or spillage if safe to do so, control dust generation
Cleanup Procedures: Sweep up and collect material using equipment designed to minimize airborne dust; transfer to a suitable container for disposal
Decontamination: Wash spill area thoroughly with water
Safe Handling Advice: Handle in a well-ventilated area, minimize dust formation, avoid inhalation and contact with skin and eyes, keep away from sources of ignition
Hygiene Practices: Wash hands and face before breaks and at end of work, do not eat, drink or smoke while working
Storage Conditions: Store in a cool, dry, well-ventilated place, keep container tightly closed, protect from light and moisture
Incompatible Materials: Strong oxidizers, acids, alkalis
Packaging Materials: Food-grade polyethylene or laminated paper bags with moisture barrier
Exposure Limits: No established occupational exposure limits for Casein Phosphopeptide
Engineering Controls: Use local exhaust ventilation to control airborne dust, process enclosure recommended
Personal Protective Equipment:
Eye Protection: Safety goggles or face shield
Skin Protection: Lab coat or protective clothing, nitrile or latex gloves
Respiratory Protection: Dust mask (P2 or FFP2) recommended under dust-generating conditions
General Safety Measures: Do not allow material to contact eyes, skin, or clothing; practice good occupational hygiene
State: Powder or granule
Color: Off-white to pale yellow
Odor: Faint, typical protein/peptide scent
Molecular Weight: Mixture of peptides; average MW approximately 2,000-4,000 Da
pH (1% solution): 6.0–8.0
Solubility in Water: Freely soluble, forms clear to slightly opalescent solutions
Melting Point: Not applicable
Boiling Point: Not applicable
Flash Point: Not applicable
Bulk Density: 0.3–0.5 g/cm³
Particle Size: Typically 80–500 microns
Stability in Water: Stable
Chemical Stability: Product remains stable under normal storage and handling conditions
Reactivity: Not reactive under recommended conditions of use
Conditions to Avoid: Moisture, open flames, high temperatures, strong oxidizing agents
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides produced upon thermal decomposition
Polymerization: Does not occur
Incompatible Materials: Strong acids, bases, strong oxidizers
Acute Toxicity: Not classified as toxic; oral LD50 expected to be greater than 5,000 mg/kg in rats (data based on similar milk peptides)
Possible Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Irritation: Slight irritation possible in sensitive persons on inhalation, contact, or ingestion
Sensitization: May trigger allergic responses in individuals sensitive to milk or dairy proteins
Chronic Effects: No evidence of chronic toxicity or carcinogenicity; not listed by NTP, IARC, OSHA as carcinogenic
Mutagenicity: Negative in standard genotoxicity assays (as tested for similar protein hydrolysates)
Reproductive Toxicity: Not expected based on available data
Ecotoxicity: Not anticipated to present significant environmental hazards in small or diluted quantities; rapidly degraded by bacteria in soil and water
Aquatic Toxicity: No evidence of toxicity to aquatic organisms at environmentally relevant concentrations
Persistence and Degradability: Biodegradable; breaks down to amino acids and phosphate
Bioaccumulation: Not expected
Mobility in Soil: Moderate, depending on environmental conditions
Additional Information: Not considered hazardous for the environment when handled according to regulations
Product Disposal: Dispose of contents/containers in accordance with national/regional/local regulations; landfill or incinerate if permitted
Unused Product: Can be discarded as non-hazardous solid waste in most jurisdictions
Contaminated Packaging: Rinse thoroughly before reuse or recycling, otherwise treat as product waste
Special Precautions: Prevent release to the environment by proper disposal methods; avoid dust
UN Number: Not regulated
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified as dangerous goods under ADR, IMDG, IATA
Packing Group: Not assigned
Marine Pollutant: No
Special Precautions for User: Protect from moisture and physical damage during transport
Transport in Bulk: Conduct transport practices to prevent dust release and contamination of other cargo
International Inventories: Ingredient registered or notified under food and chemical inventories including US (FDA GRAS), EU (EFSA, Novel Food), Japan (FOSHU)
Labeling Requirements: Food and pharmaceutical applications require labeling of milk origin
OSHA: Not listed as hazardous
EPA: Not regulated as hazardous waste
REACH: Exempt as food additive
Other Regulations: Subject to food safety and purity standards in most consumer markets; always observe local health and safety regulations
