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Material Safety Data Sheet for Carmosine

Identification

Product Name: Carmosine
Synonyms: Azorubine, Food Red 3, Acid Red 14
Chemical Formula: C20H12N2Na2O7S2
CAS Number: 3567-69-9
Recommended Uses: Coloring agent in food, pharmaceuticals, and cosmetics
Supplier and Contact: Manufacturer name, address, telephone number, emergency contact information
Emergency overview: Bright red synthetic powder or granules, slight odor, mainly used as a dye additive

Hazard Identification

GHS Classification: Not classified as hazardous according to GHS
Main Hazards: May cause irritation to eyes, skin, and respiratory tract
Possible Health Effects: Inhalation, ingestion, or contact may cause mild allergic reaction in sensitive individuals, rarely triggers asthma
Label Elements: None required under international guidelines
Environment: Large concentrations may affect aquatic organisms, rarely found outside of wastewater streams in significant amounts

Composition / Information on Ingredients

Chemical Name: Carmosine
Content: 80-95% pure dye, traces of sodium chloride and sulfate possible
Molecular Weight: 502.43 g/mol
Impurities: May contain unreacted intermediates from manufacture in trace amounts
Ingredient Disclosure: Dye content high; other ingredients typically sodium chloride, sodium sulfate, water (in negligible amounts)

First Aid Measures

Inhalation: Move person to fresh air, reassure, seek help for breathing difficulty, wash out mouth
Skin Contact: Wash immediately with soap and plenty of water, remove contaminated clothing, persistent irritation needs medical advice
Eye Contact: Rinse under running water for several minutes, remove contact lenses, medical attention if symptoms do not improve
Ingestion: Rinse mouth immediately, seek medical advice, do not induce vomiting unless instructed by professional

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Hazardous Combustion Products: Emits oxides of sulfur, nitrogen, and sodium when burned
Special Fire Fighting Procedures: Wear self-contained breathing apparatus and protective clothing, avoid smoke inhalation, use standard firefighting methods for chemical fires
Unusual Fire Hazards: Dust can form explosive mixtures with air but rarely poses risk at normal workplace concentrations

Accidental Release Measures

Personal Precautions: Use protective equipment such as gloves, safety goggles, dust mask
Spill Cleanup: Avoid creating dust, sweep up material carefully, place in suitable container for disposal, wash spill area with water
Environmental Precautions: Do not let dye enter drains or waterways, large releases can impact local water color and aquatic life

Handling and Storage

Safe Handling: Avoid contact with eyes, skin, and clothing, wash hands after handling, do not eat/drink/smoke while handling
Storage: Keep container tightly closed, store in a cool, dry, well-ventilated place, keep away from food or strong oxidizing agents
Incompatible Materials: Strong oxidizers, acids, alkalis
Recommendations: Use only approved containers, label clearly for content and hazard

Exposure Controls and Personal Protection

Occupational Exposure Limit: Not established in most jurisdictions
Engineering Controls: Use local exhaust or general ventilation to control airborne dust
Personal Protection: Wear protective gloves, lab coat or apron, safety glasses or goggles
Respiratory Protection: Dust mask or respirator for high concentrations
Hygiene Measures: Wash hands after use, remove contaminated clothing, avoid breathing powder

Physical and Chemical Properties

Appearance: Bright red to maroon powder or granules
Odor: Slight odor
Melting Point: Decomposes above 300°C
pH Value (1% Solution): 4.0 – 6.5
Solubility: Soluble in water, produces deep red solution
Boiling Point: Not applicable (decomposes)
Relative Density: Approximately 0.9-1.2 g/cm³
Flash Point: Not flammable under standard conditions
Vapor Pressure: Negligible at room temperature
Auto-Ignition Temperature: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal conditions
Reactive Conditions: High temperatures cause decomposition
Incompatible Materials: Strong oxidizing agents, strong acids and alkalis degrade dye
Decomposition Products: Sodium oxides, sulfur oxides, nitrogen oxides, released under fire conditions
Polymerization: Does not occur

Toxicological Information

Acute Toxicity: Oral LD50 (rat) estimated above 2000 mg/kg
Skin Irritation: Low, rare sensitization
Eye Irritation: Possible redness, stinging
Inhalation: Dust may cause irritation
Long-term Exposure: Animal studies show no significant carcinogenic or mutagenic risk at normal human exposure
Allergenicity: Rare reports of hives or mild allergic reactions in sensitive individuals
Other Effects: No known reproductive or developmental toxicity

Ecological Information

Ecotoxicity: Moderately toxic to aquatic organisms in concentrated form, risk to environment low in diluted conditions
Persistence and Degradability: Breaks down slowly in aquatic environments under exposure to sunlight and microorganisms
Bioaccumulation: Does not significantly bioaccumulate in aquatic species
Mobility in Soil: Moves slowly due to large molecular weight and charge, small risk of groundwater contamination
Other Adverse Effects: Highly visible red color can affect appearance of water bodies even at low levels

Disposal Considerations

Waste Disposal Methods: Dispose of by controlled landfill or incineration in compliance with local regulations
Container Disposal: Empty packaging should be rinsed, punctured, disposed of as non-hazardous unless contaminated
Avoid Release: Do not discharge concentrated product to natural waterways
Preferred Disposal: Engage qualified waste contractor for large quantities

Transport Information

UN Number: Not classified as hazardous for transport
Shipping Class: Not regulated as dangerous goods
Packing Group: N/A
Proper Shipping Name: Carmosine dye
Labeling Required: None required for road, sea, or air
Additional Info: Avoid dust generation and keep containers sealed during transit

Regulatory Information

International Regulations: Approved for use as food additive (E122) in EU, not approved in US, status varies by country
Occupational Regulations: Not listed as hazardous substance under OSHA, does not require workplace exposure monitoring unless dust is present
Environmental Regulations: Subject to discharge limits in wastewater under some local environmental laws
Labeling Requirements: Food products must declare Carmosine on ingredient list
Restrictions: Banned in some countries for infant food, limited use in others due to allergen risk