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Material Safety Data Sheet for Calcium Gluconate

Identification

Product Name: Calcium Gluconate
Chemical Formula: C12H22CaO14
CAS Number: 299-28-5
Relevant Identified Uses: Pharmaceutical ingredient, food additive, laboratory chemical
Manufacturer: [Manufacturer Name and Address]
Supplier Contact: [Supplier Information with Emergency Phone Number]
Synonyms: Gluconic acid calcium salt, Calcium salt of gluconic acid
Recommended Use: Recommended for laboratory and research applications, medical treatment for hydrofluoric acid burns
Restrictions on Use: Not intended for direct human consumption except under professional supervision

Hazard Identification

GHS Classification: Not classified as hazardous under GHS
Signal Word: None
Hazard Statements: May cause mild irritation to eyes or skin in sensitive individuals
Precautionary Statements: Avoid eye and prolonged skin contact, use personal protective equipment if dust could be generated
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Mild irritation to respiratory tract, eyes, or skin can develop; ingestion of large amounts may result in gastrointestinal discomfort
NFPA Ratings: Health: 1, Flammability: 0, Reactivity: 0

Composition / Information on Ingredients

Substance: Calcium Gluconate
Chemical Name: Calcium Gluconate
Concentration: 98–100%
Additional Ingredients: None
Impurities: May contain trace amounts of water due to hygroscopic nature
Molecular Weight: 430.37 g/mol

First Aid Measures

Inhalation: Move individual to fresh air; seek medical attention if symptoms persist
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing; seek medical advice if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing; seek attention if redness or pain continues
Ingestion: Rinse mouth with water; do not induce vomiting; seek medical assistance if large quantities swallowed or discomfort occurs
Most Important Symptoms: Redness, irritation, possible stomach upset after ingestion; rare allergic reactions
Advice for Medical Personnel: Symptomatic and supportive care
Note to Doctor: No specific antidote identified, treat based on patient’s symptoms

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Unsuitable Media: None known
Hazardous Combustion Products: Carbon oxides, calcium oxides
Specific Hazards: Product is stable and not flammable, but containers could rupture in a fire situation
Advice for Firefighters: Wear self-contained breathing apparatus and protective clothing
Protective Equipment Required: Standard firefighting turnout gear is recommended
Special Procedures: Prevent runoff from contaminating water sources

Accidental Release Measures

Personal Precautions: Wear suitable gloves, goggles, dust mask if airborne dust is a concern
Environmental Precautions: Avoid direct release to waterways or drains; inform environmental authorities if a major spill occurs
Methods for Containment: Sweep up and place in appropriate containers for disposal; avoid formation of dust
Cleaning Methods: Clean spill area with water after material pickup
Reference to Other Sections: Wear appropriate PPE as described in Exposure Controls

Handling and Storage

Handling: Keep container tightly closed; handle in well-ventilated area; minimize dust generation; avoid breathing dust
Storage Conditions: Store in a cool, dry, and well-ventilated environment; keep away from moisture; use moisture-proof containers
Incompatibilities: Strong oxidizers, acids
Specific End Uses: Store out of reach of children; for laboratory, industrial or healthcare settings only

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established ACGIH or OSHA limits for calcium gluconate
Engineering Controls: Use local exhaust ventilation if dust produced; keep dust levels as low as possible
Personal Protective Equipment: Gloves (nitrile or latex), chemical safety goggles, lab coat
Respiratory Protection: Use NIOSH-approved dust respirator in cases of dust generation
General Hygiene Measures: Wash hands after handling; avoid eating, drinking, or smoking during use; launder contaminated clothing before reuse
Environmental Controls: Prevent dust from entering drains or watercourses

Physical and Chemical Properties

Appearance: White to off-white powder, odorless
Odor: Odorless
pH: Approx. 6.5–8.5 (10% solution in water)
Melting Point/Freezing Point: Decomposes without melting at approx. 120°C
Boiling Point: Not applicable
Flash Point: Not combustible
Flammability (solid/gas): Not flammable
Vapor Pressure: Not applicable
Density: 1.7 g/cm3
Solubility (water): 3.5 g/100 ml at 25°C
Partition Coefficient (n-octanol/water): Not determined
Evaporation Rate: Not applicable
Auto-Ignition Temperature: Not self-igniting
Decomposition Temperature: 120°C

Stability and Reactivity

Chemical Stability: Stable under normal conditions
Reactivity: Non-reactive in ambient conditions
Conditions to Avoid: Excessive moisture, heat, strong acids or bases
Incompatible Materials: Strong oxidizers, mineral acids
Hazardous Decomposition Products: Releases carbon oxides and calcium oxide at high temperature
Polymerization: Will not occur

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: Low toxicity; oral LD50 (rat): >2000 mg/kg
Chronic Effects: No chronic health data available for humans at low exposure
Skin Irritation: Mild, in rare cases
Eye Irritation: Possible mild irritation
Respiratory Sensitization: Unlikely but possible in sensitive individuals
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: Not demonstrated in animal studies or epidemiological data
Mutagenicity: Not observed in standard tests
Other Effects: Allergic reactions have been rare; overexposure through ingestion could lead to hypercalcemia in extreme cases

Ecological Information

Aquatic Toxicity: Not expected to be toxic to aquatic life; calcium gluconate dissociates into naturally occurring substances
Persistence and Degradability: Readily biodegradable
Bioaccumulative Potential: No potential for bioaccumulation
Mobility in Soil: High mobility due to good water solubility
Other Adverse Effects: No known large-scale risk to aquatic or terrestrial systems, proper disposal prevents unnecessary nutrient loading

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local and national regulations; material is non-hazardous waste
Packaging Disposal: Clean containers may be recycled or disposed of as non-hazardous waste
Special Precautions for Landfill or Incineration: Avoid release to water bodies; do not incinerate in closed containers

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified
Packing Group: Not applicable
Environmental Hazards: Not environmentally hazardous
Special Transport Precautions: Prevent package damage; avoid exposure to moisture during transportation by using sealed containers; secure against movement during transit

Regulatory Information

Global Inventory Status: Listed in TSCA (USA), EINECS/ELINCS (EU), DSL (Canada), AICS (Australia), ENCS (Japan)
SARA Title III: Not regulated
DSL/NDSL (Canada): Listed
California Proposition 65: Not listed
EU Classification: Not classified as hazardous
Labelling Requirements: No special labeling required for industrial/commercial handling
Workplace Regulations: Observe standard laboratory or industrial hygiene protocols
Other Regulatory Information: No special restrictions on import, export, or use apart from standard safety procedures