Product Name: Calcium Cyclamate
Synonyms: Calcium N-cyclohexylsulfamate
Chemical Formula: C12H24CaN2O6S2
CAS Number: 139-05-9
Use: Artificial sweetener, food additive, pharmaceutical excipient
Manufacturer: Contact local supplier or manufacturer for specific data
Emergency Contact: Refer to supplier or local country regulations for emergency hotline
WHO Hazard Classification: Not classified as hazardous according to GHS criteria
Routes of Exposure: Inhalation, ingestion, dermal, and ocular contact
Potential Health Effects: Low acute toxicity; can cause mild irritation to eyes or respiratory tract if particulates are inhaled; people with sulfonamide allergies may react
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Signal Word: None
Hazard Pictograms: None required by GHS
Precautionary Statement: Avoid creating dust; minimize direct handling; maintain good housekeeping
Chemical Name: Calcium Cyclamate
Purity: 98-100%
Impurities: None known in significant concentrations
Other Components: No hazardous impurities specified
Inhalation: Remove to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash affected skin with soap and water
Eye Contact: Rinse eyes gently with plenty of water for at least 15 minutes, seek medical advice if irritation continues
Ingestion: Rinse mouth, drink water, consult a physician if large quantities are swallowed or symptoms develop
Most Important Symptoms: May cause mild irritation to eyes; large ingestion could cause gastrointestinal discomfort such as nausea or diarrhea
Special Note: No specific antidotes known; treat symptoms as needed
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Hazardous Combustion Products: Potential release of carbon oxides, nitrogen oxides, sulfur oxides, calcium oxide at high temperatures
Explosion Hazard: Not known to be explosive; does not support combustion
Firefighting Instructions: Wear self-contained breathing apparatus; avoid inhalation of combustion products; use standard protective equipment
Special Hazards: Fine dust may form explosive mixtures with air; control dust generation in storage or handling areas
Personal Precautions: Use appropriate personal protective equipment, avoid generating dust, ensure adequate ventilation
Environmental Precautions: Prevent spillage from entering drains or watercourses
Cleanup Methods: Sweep up and collect using dustless methods, place in suitable container for disposal, clean area with water if necessary
Spill Reporting: Notify local authorities as required, especially if spill impacts the environment
Handling: Handle in well-ventilated areas, minimize dust formation, avoid breathing powder, wash hands after handling, keep away from incompatible materials such as strong oxidizers
Storage Conditions: Store in a cool, dry, well-ventilated place in tightly closed containers, away from sources of moisture and direct sunlight
Incompatibilities: Strong acids, oxidizing agents
Packaging Materials: Store in original packaging or containers compatible with food-grade ingredients
Occupational Exposure Limits: No established limit for Calcium Cyclamate; follow local workplace guidelines for dust exposure
Engineering Controls: Use local exhaust ventilation if dust generation cannot be minimized
Personal Protection: Use safety glasses with side shields, gloves resistant to chemical penetration for repeated exposure, dust mask or respirator when handling large volumes
Hygiene Measures: Wash hands after handling, do not eat or drink in areas where product is handled
Environmental Controls: Prevent product release into waterways or sewers
Appearance: White, odorless crystalline or granular powder
Odor: None
Odor Threshold: Not applicable
pH: 5.5–7.5 in 10% aqueous solution
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility: Freely soluble in water
Density: 1.83 g/cm³
Vapor Pressure: Not applicable
Partition Coefficient (n-octanol/water): Not available
Evaporation Rate: Not applicable
Flammability: Not flammable under normal conditions
Molecular Weight: 444.54 g/mol
Chemical Stability: Stable under normal conditions of storage and use
Reactivity: No hazardous reactions under normal handling
Hazardous Decomposition Products: With strong acids or excessive heat, sulfur oxides and nitrogen oxides can form
Incompatible Materials: Strong oxidizing agents, strong acids
Polymerization: Will not occur
Acute Toxicity: Oral LD50 (rat): >17,000 mg/kg; generally considered low toxicity
Skin Corrosion/Irritation: Not a skin irritant in animal studies
Serious Eye Damage/Irritation: May cause mild mechanical irritation
Respiratory Sensitization: Not expected under normal use
Chronic Effects: Long-term feeding studies in animals indicate no significant health effects at normal dietary levels
Reproductive Toxicity: Studies do not show reproductive hazards at permitted levels; avoid excessive exposure
Mutagenicity: Tests indicate no genetic toxicity at relevant concentrations
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, ACGIH, or OSHA
Ecotoxicity: Low aquatic toxicity; LC50 (fish, 96h): >100 mg/L
Persistence and Degradability: Readily biodegradable by microorganisms
Bioaccumulation Potential: Not expected to bioaccumulate
Mobility in Soil: Moderately mobile in water; soluble and may leach in soil if large quantities are released
Other Adverse Effects: No evidence of significant environmental impact at recommended usage levels
Disposal Methods: Dispose in accordance with local, regional, and national regulations; do not discharge large amounts into environment
Packaging Disposal: Recycle or dispose of containers as per local waste guidelines; wash out containers before disposal if possible
Special Precautions: Prevent unintentional release into sewers and waterways
UN Number: Not classified as dangerous goods for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for User: Avoid excessive dust generation during loading or unloading
DOT, IATA, IMDG: Not subject to transport regulations for dangerous goods
GHS Classification: Not a hazardous chemical under GHS
FDA Status: Permitted as a food additive in some countries within specified limits
EU Status: E952, authorized subtype food additive
TSCA Inventory: Listed
REACH Status: Registered or exempt in the EU
SARA Title III Sections 302/304/313: Not listed
WHMIS Classification: Not a controlled product
Right-To-Know: Not listed by California Proposition 65
Other Local Regulations: Check country-specific food safety and environmental protection agencies for additional requirements