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Product Name: Calcium Citrate Tetrahydrate
Chemical Formula: Ca3(C6H5O7)2·4H2O
CAS Number: 5785-44-4
EC Number: 212-391-7
Synonyms: Citric acid calcium salt tetrahydrate
Recommended Use: Nutritional supplement, food additive, laboratory reagent
Manufacturer Contact: Refer to supplier contact details directly on label or purchase documentation, which lists physical address, telephone, and emergency numbers.
Classification: Not classified as hazardous according to GHS standards
Main Hazards: Inhalation of dust may cause mild respiratory tract irritation; direct eye contact may cause mechanical irritation; swallowing large amounts may upset stomach
Signal Word: None assigned
Hazard Statements: May cause eye or respiratory irritation when exposed to dust
Precautionary Statements: Avoid inhalation of dust, wash hands after handling, use in well-ventilated places
Substance: Calcium Citrate Tetrahydrate
Purity: Typically greater than 98%
Impurities/Additives: Small percentages of water, no known hazardous impurities
Ingredient Information: Calcium (approx. 20% wt), citrate ions, water of hydration (4 molecules per formula unit)
Inhalation: Remove to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash with soap and water; remove contaminated clothing
Eye Contact: Immediately rinse with plenty of water for several minutes, seek medical attention if irritation continues
Ingestion: Rinse mouth thoroughly, drink water; do not induce vomiting, medical attention typically not required for small amounts
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Specific Hazards: Product does not burn; fire or excessive heating may produce irritating or toxic fumes such as oxides of carbon
Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective gear when fighting chemical fires
Explosion Data: Product is not explosive and does not sustain combustion
Personal Precautions: Avoid dust formation, use proper personal protective equipment such as gloves, goggles, and dust mask if required
Environmental Precautions: Prevent excessive amounts entering water courses
Clean-Up Methods: Collect spilled material using mechanical means into a suitable receptacle for reuse or disposal, wash spill area thoroughly with water
Handling Guidance: Use with adequate ventilation; minimize dust generation; wash hands after handling; keep container closed when not in use
Storage Conditions: Store in a cool, dry, well-ventilated area, protect from moisture and incompatible substances, keep away from strong acids and strong oxidizers
Packaging Materials: Compatible with polyethylene or fiber containers sealed to avoid moisture uptake
Occupational Exposure Limits: No established limits for this compound; good industrial hygiene involves controlling dust exposure to below nuisance levels (as per OSHA standards)
Engineering Controls: Use local exhaust ventilation to control dust
Personal Protective Equipment: Use goggles or glasses with side shields, dust mask or respirator if high levels of dust are present, gloves to prevent skin contact
Appearance: White, odorless crystalline powder
Odor: Odorless
pH (1% solution): Range 6.5 to 8.5
Melting Point: Decomposes before melting
Boiling Point: Not applicable (decomposes)
Solubility in Water: Slightly soluble at room temperature, increases with temperature
Vapor Pressure: Not applicable
Density: 1.6–1.7 g/cm³
Decomposition Temperature: Above 210°C
Partition Coefficient (n-octanol/water): Not determined
Chemical Stability: Stable under recommended storage conditions
Incompatible Materials: Strong acids and strong oxidizers may react; avoid mixing with moisture sensitive chemicals
Hazardous Polymerization: Will not occur
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide under extreme heat; calcium oxide possible
Acute Toxicity: Low toxicity by oral, dermal, or inhalation routes
Potential Health Effects: Overexposure to dust may irritate respiratory tract or eyes; no chronic hazards at typical exposure levels in food or supplements
Carcinogenicity: Not listed as a carcinogen by NTP, IARC, or OSHA
Mutagenicity: No evidence of mutagenicity present
Reproductive Toxicity: Not associated with reproductive toxicity in available studies
Ecotoxicity: Low, product breaks down into natural minerals and citrate in the environment
Persistence and Degradability: Compound is biodegradable, both calcium and citrate are commonly found in soil and water
Bioaccumulation Potential: Not expected to bioaccumulate
Mobility in Soil: Water soluble component may move through soil into groundwater, minimal hazard due to nature and low toxicity
Other Adverse Effects: Not expected to produce significant environmental impact at normal usage levels
Waste Disposal: Dispose in accordance with local, regional, or national regulations
Product Waste: Small quantities can be disposed of in normal waste; large amounts should be sent to sanitary landfill or appropriate waste processor
Contaminated Packaging: Empty containers can be reused or recycled after thorough cleaning, or disposed as non-hazardous solid waste
UN Number: Not regulated
Proper Shipping Name: Not classified as dangerous for transport
Transport Hazard Class: Not restricted
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Protect from moisture and rough handling during transit
Inventory Listings: Listed on TSCA (US), EINECS/ELINCS (EU), DSL (Canada), AICS (Australia), other chemical inventories
Labelling Requirements: Not required according to GHS or EU CLP criteria
Food Additive Regulations: Approved for use as a food additive in many jurisdictions (e.g., FDA GRAS, EFSA registered food additive)
Occupational Safety: Follow workplace control standards for nuisance particulates
Other Standards: Compliant with REACH, FDA, and food code regulations on purity and handling where applicable
