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Calcium Citrate Anhydrous: A Comprehensive Look

Historical Development

People discovered calcium citrate centuries ago, even though the pure, anhydrous form took a while to isolate. As the chemistry of nutrition grew in the 19th and 20th centuries, researchers noticed how calcium played into bone health and muscle function. They tried different forms, realizing not every compound worked the same in the body. Citric acid, coming from citrus fruits, ended up as a safe and available base, so chemists started binding it with calcium. Industrial scaling picked up in the 1970s and 1980s, matching the explosion in vitamin and supplement use. Large manufacturers then pushed for more stable, easier-to-handle calcium salts, paving the way for the anhydrous version. Nowadays, it holds a spot among the main calcium sources in the nutrition, pharmaceutical, and food world.

Product Overview

Calcium citrate anhydrous stands out for more than just being calcium. It shows up as a white, almost tasteless or slightly bitter powder. Manufacturers sell it for dietary uses, pharmaceuticals, and food fortification. While other calcium compounds can clump or react in mixtures, this form gives better consistency in processing. Nutritionists recommend it to people who need calcium without a big dose of acid in the gut, like those with sensitivity to high-acid supplements. This compound gets into everything from antacid tablets to dairy alternatives and sports drinks. Companies appreciate its ability to deliver calcium with a predictable dose and less stomach upset for sensitive folks.

Physical & Chemical Properties

This powder stays stable in room conditions, doesn’t hang onto moisture like some hydrated calcium salts, and dissolves a little better in water than plain calcium carbonate. That slight edge in solubility makes it valuable not just for its mineral content, but for its ease in blending with liquids and foods. Its molecular formula is Ca3(C6H5O7)2 — a combination tying each calcium atom with a three-citrate linker, without any water molecules stuck in the structure. The melting point sits high, making it suitable for various processing conditions. In the lab, it resists breaking down in mild temperatures and doesn’t easily react with air, which means a longer shelf life for products containing it.

Technical Specifications & Labeling

Anyone picking up a bottle or a bulk bag expects certain standards. Regulations call for clear calcium content, purity, and other quality control numbers. Labels specify percentage calcium—about 21% elemental by weight. Pharmacopeias across the globe set limits on impurities like heavy metals, and testing labs watch for consistency from batch to batch. Manufacturers must keep track of particle size, moisture content, and signs of impurity. Certificates of analysis and standard labeling make sure product claims line up with what’s inside, which matters both to consumers and inspectors. Adulteration scandals, especially with food supplements in some regions, have made traceability and raw material documentation non-negotiable for any serious supplier in this field.

Preparation Method

Chemists kick off the synthesis using citric acid, neutralizing it with a calcium compound, often calcium hydroxide or calcium carbonate, in water. The mixture reacts, forming calcium citrate, which starts out as a hydrated salt. To get the anhydrous version, manufacturers remove water by careful heating or under vacuum. This step takes finesse—too much heat can degrade the compound or create unwanted byproducts. Industrial processes use controlled temperatures, continuous monitoring, and quick drying cycles to hit the sweet spot between purity and efficiency. Each plant might have minor tweaks, but the foundation never changes: mix, react, isolate, and dry.

Chemical Reactions & Modifications

Calcium citrate anhydrous doesn’t act flashy in the lab—as a salt, it stays stable under normal handling. Drop it into strong acid and it breaks apart, releasing calcium ions and citric acid, though this doesn’t usually matter in food or pharmaceutical use, unless someone is trying to mask taste or slow absorption. The molecule can take part in chelation reactions, binding with trace metals, a feature scientists use in specialized cleaning agents and in forming stable supplements. Modifications tend to involve particle size or coating, not chemistry, to tailor the compound for specific uses in chewable tablets or powders. The big chemical shift happens if it’s exposed to moisture, where it may rehydrate, so careful storage matters.

Synonyms & Product Names

Walk through a store or browse online, and calcium citrate anhydrous often pops up under different names. Names like “tricalcium dicitrate,” or in some catalogs, just “Calcium Citrate.” Add “anhydrous” to make it clear there’s no water in the structure, since hydrated forms work slightly differently. In medical settings, the code numbers or international nonproprietary names (INN) help keep things straight, yet buyers still want plain language to know they’re getting the right material—so suppliers balance chemical precision with easy-to-read labels. Brands might call it “Super Calcium,” “Digest-Ease Calcium,” or other wellness-driven terms, reflecting the consumer push toward bioavailable minerals.

Safety & Operational Standards

Health agencies and multinational regulators have plenty to say about supplement ingredients, and calcium citrate anhydrous falls under their close watch. The FDA, EMA, and similar groups insist on testing for contaminants, safe production practices, and full documentation. Handling it in bulk means workers use masks and gloves to keep fine dust out of airways. Facilities keep powders in sealed bags under low humidity, as extra moisture can clump the product. From the supply chain side, transparency around source materials and plant conditions keeps consumer trust intact—and recalls rare. Finished tablets or foods don’t carry the same risks, but manufacturers still log every step, from ingredient entry to package sealing, all in line with Good Manufacturing Practices (GMP).

Application Area

Doctors recommend this compound to people needing safe and dependable calcium—especially if dairy isn’t an option. Dietitians highlight its role in bone growth for kids and maintenance in adults, as well as uses in pregnancy or recovery from injury. Food producers mix it into cereals, juices, and flour, boosting the nutrition label where local diets lack dairy sources. Pharmaceutical syrups and chewables use it for its gentle absorption. Pet food developers turn to it, trusting animal safety data. Even industrial cleaners tap into its chelating power, pulling out unwanted metal ions from machinery and water lines. This versatility springs from its chemical structure and safety record, not just tradition.

Research & Development

Scientists haven’t let up in trying to squeeze more performance from calcium citrate anhydrous. They study how particle size affects how body tissue absorbs calcium, or test microencapsulation to mask taste, especially for picky patients. Researchers track bioavailability in every new tablet format, using blood and bone scans to compare it with both traditional carbonate and organic-fortified forms. Recent studies focus on ways to combine this calcium with vitamins D and K or magnesium, promoting bone synergy and preventing kidney stones. There’s also a spotlight on how it works in special populations: seniors with digestion issues, or post-surgery patients with unique absorption needs.

Toxicity Research

Long-term health hinges not just on benefits, but on risk. Toxicity research into calcium citrate anhydrous covers acute exposure, long-term intake, and rare allergies. Trials show safe daily doses far above what most people would ever eat, but as with any calcium salt, too much can build up in the bloodstream, leading to hypercalcemia. Researchers keep tabs on kidney function and mineral balance in heavy users, combining clinical trial results with animal studies. Supplements earning FDA or EFSA approval must pass tough scrutiny on everything from manufacturing residues to batch contaminants. No links have arisen between pure calcium citrate anhydrous and carcinogenicity or reproductive harm, though all supplements stay under periodic review by agencies as usage patterns shift across decades.

Future Prospects

Looking forward, a few trends point to where things might go. Aging populations boost the demand for bone-supporting nutrients. Plant-based diets need better sources of bioavailable calcium. Manufacturers seek greener, more energy-efficient production, exploring lower-waste synthesis and biodegradable packaging. Some research teams even test new delivery systems for calcium citrate anhydrous, such as time-release capsules or probiotic blends, hoping to boost how well the body holds onto calcium over a lifespan. Consumer expectations push for transparent sourcing, clean labeling, and traceability from raw material through final sale, tightening the weave of safety nets around the entire industry. If these needs keep growing, the future belongs to companies and researchers who can match science, safety, and sustainability in every batch.




What is Calcium Citrate Anhydrous used for?

Meeting Real Nutritional Needs

Walk through any pharmacy or supermarket and you’ll spot shelves lined with supplements. Many people look for calcium supplements, sometimes because their doctor suggested them, sometimes out of their own worry about bone health. One version, calcium citrate anhydrous, stands out for a simple reason: it fits in with people’s busy lives and changing dietary habits.

Lately, more folks are reading up on the difference between forms of calcium. For example, calcium carbonate has been the old standby, but it needs stomach acid to break down. People who have taken antacids, or deal with low stomach acid, may not get much benefit from it. Years ago, after my own stomach surgery, the doctor said, “Switch to calcium citrate.” Turns out, this form absorbs well without relying on a sour stomach. Science backs this up—research from the National Institutes of Health shows that calcium citrate delivers more absorbable calcium, especially for people over 50.

More Than Just Strong Bones

Media coverage keeps hammering home the message that calcium means bone strength. While this is true, there’s more to it. Athletes who sweat a lot, post-menopausal women, vegans, and people with lactose intolerance often get less dietary calcium. Skipping dairy means a gap forms, and not everyone likes leafy greens enough to close it. I’ve heard from friends who switched to calcium citrate anhydrous simply because it was easier on their stomach and slid right into their morning routine.

The fact that this form doesn’t pull water from the air makes it great for simple chewables or swallow tablets. That’s why many supplement brands use it—no clumping, no chalkiness, just straight-up convenience for manufacturers and customers alike.

Tackling Deficiencies and Getting Practical

Calcium shortfalls create real problems. The World Health Organization reports lower bone density in countries where diets have less calcium. The toll surfaces later, as broken bones and hospital visits pile up. Some folks try food fortification, mixing minerals into juice or plant-based milk, but absorption matters. Calcium citrate anhydrous gives better bang for the buck, especially for those dealing with digestive issues. A study out of Tufts University put it plainly: these pills made it easier for people to meet daily calcium targets, and sticking with the habit meant fewer falls and fractures years down the road.

The supplement also pairs nicely with vitamin D, which almost everyone in colder climates needs more of. I remember the push by public health groups for vitamin D and calcium during COVID-19, reminding people that a healthy skeleton means better whole-body strength. Anyone who’s watched an aging parent struggle after a fall sees just how important this becomes.

How to Use It (and Not Overdo It)

Supplements tempt people to think more is better, but overdosing on calcium just creates new problems. Kidney stones, heart troubles—these risks build up with heavy, daily use. Personally, my doctor suggested splitting up the dose, taking some with meals, and mixing supplement use with leafy vegetables and nuts. The goal? Keep numbers in the healthy range, not skyrocket them.

Real answers don’t come from any single pill. Doctors, pharmacists, and nutritionists can guide each person based on their unique story. They’ll check blood levels, review medications, and look at family history. This tailored help makes all the difference between feeling better and accidentally making things worse.

Choosing calcium citrate anhydrous isn’t just about grabbing what’s new. It grows from genuine needs in modern life: changing diets, aging, digestive issues, and a push to keep everyone upright and active.

How is Calcium Citrate Anhydrous different from other forms of calcium?

Why Choosing a Calcium Supplement Isn’t Always Simple

Calcium keeps bones strong, nerves firing properly, and muscles contracting. Still, picking the right form can take some digging. Walking through a pharmacy aisle, most folks notice shelves packed with calcium carbonate, calcium citrate, and sometimes the lesser-seen calcium citrate anhydrous. Each type has its quirks that make a difference far beyond the nutrition label.

Understanding the “Anhydrous” Advantage

I’ve tried both standard calcium citrate tablets and the “anhydrous” version. That one word—anhydrous—means the supplement doesn’t carry any water molecules. Sounds technical, but the impact is pretty real. Without water making up part of the tablet, anhydrous formulas cram in more actual calcium by weight.

Take calcium carbonate. This common supplement carries a lot of calcium per serving, but it’s not gentle on everyone’s stomach. Anyone who’s dealt with indigestion after popping chalky antacids has learned this firsthand. The body only absorbs calcium carbonate well if there’s enough stomach acid around, which isn’t always the case for older adults or those using acid-reducing medications.

Calcium citrate—anhydrous or not—sidesteps that issue. Its structure lets it dissolve in lower-acid environments. People who’ve faced digestive trouble or simply want to take their calcium with or without food tend to reach for citrate-based options. But the anhydrous form brings an added practical boost: smaller pills and, potentially, lower doses to hit the same daily targets.

Bioavailability: How Much Gets Through?

All calcium sources tell you how many milligrams you’re getting, but the body won’t use every bit of it. Absorption rates count just as much as the number printed on the bottle. Research and experience point out that calcium citrate anhydrous scores higher in bioavailability compared with carbonate. A study from the Journal of Clinical Pharmacology showed that healthy women absorbed calcium citrate better than calcium carbonate, whether or not they took it with a meal.

Those seeking to support bone strength—especially with age or after a diagnosis of osteoporosis—are dealing with a higher risk of not getting enough calcium from diet alone. Calcium citrate anhydrous can close this gap because of better uptake and less stomach upset.

Safety, Additives, and Real-World Results

Reading through ingredient lists usually reveals more than calcium alone. Fillers, binders, colorants, and sweeteners can show up in some brands. Anhydrous forms sometimes need fewer additives, because they’re less bulky. If someone has allergies, sensitivities, or just likes things simple, checking for “anhydrous” on the label can help sidestep a long list of extra ingredients.

But absorption doesn’t operate in a vacuum. Vitamin D plays a huge role in actually moving calcium into bones. Without enough vitamin D, even the most bioavailable calcium won’t deliver full benefits. Paying attention to both nutrients—ideally from a health professional’s guidance—yields the best outcome.

Solutions for Better Bone Health

Staying informed helps avoid blindly following supplement trends. Before grabbing any bottle, check if your current health, medications, or diet point toward one type of calcium. Ask a doctor or a licensed dietitian, especially with a history of kidney stones or digestive issues. Choose brands that offer full transparency about sources and testing. Calcium citrate anhydrous gives a practical choice for many, but making the most of it depends on the bigger picture: diet, sun exposure, and tailored advice.

What is the recommended dosage for Calcium Citrate Anhydrous?

Understanding Dosage

Every time I read a label for a calcium supplement, the numbers look simple, but the truth shows up in the details. For Calcium Citrate Anhydrous, the standard advice suggests 500 to 600 mg of elemental calcium per dose, not exceeding 1,000–1,200 mg daily. That’s for healthy adults who don’t face any chronic illness or special circumstances. What most people don’t realize is that a tablet might show 1,000 mg of Calcium Citrate Anhydrous on the bottle, but that’s not all elemental calcium. Usually, about 21% is elemental—the rest helps with absorption. That matters, because our bones depend on the real thing.

Why Doctors Stress Individual Needs

Doctors talk about bones and heart health, but they also see patients whose absorption rates go down because of age or digestive conditions. I remember speaking with a family friend—a pharmacist—who often reminded patients that stomach acid and certain medications change the way calcium gets absorbed. He’d tell folks with low acid or who’ve had weight-loss surgery to take smaller, more frequent doses.

The National Institutes of Health states that adults 19 to 50 years old should get 1,000 mg of elemental calcium each day, and women over 50 or men over 70 need 1,200 mg. Adolescents need even more, because their bones are still growing. Pregnant or lactating women fall into a similar bracket. For these groups, hitting the right mark matters, since both too much and too little bring real problems—skeletal weakness for low intake, kidney stones and impaired absorption for high.

Balancing Supplements With Diet

Anyone thinking about calcium citrate should step back and look at their plate. Dairy is a key source. Greens and fortified juices add up, too. Supplements should top up what’s missing, not push over the recommended amount. It’s tempting to pop extra pills, but excess gets wasted or even builds up problems for kidneys and blood vessels. Dieticians will tell you—check the total from food and only supplement what’s needed. The label won’t do all the thinking.

The Role of Vitamin D and Other Factors

I’ve noticed that friends who struggle with vitamin D deficiency end up chasing their tails on calcium, since both nutrients work hand-in-hand. Even a perfect calcium intake won’t support bone health if vitamin D runs low. Many people don’t get enough sun, and even diet struggles to cover the daily requirement. That’s why physicians point out that calcium supplements often include vitamin D, or recommend checking blood levels before trying to fix things with one nutrient alone.

Certain lifestyle choices, like smoking or drinking a lot of coffee and soda, can undercut calcium absorption. Medications for blood pressure, epilepsy, or corticosteroids do the same. That’s the sort of thing that rarely lands on supplement bottles, yet it shapes how much calcium the body can use.

Better Ways to Supplement

Instead of just picking the biggest numbers on the shelf, I’ve learned to watch for how much elemental calcium each tablet delivers. Spreading the dose through the day improves absorption, especially for those who need more than the usual amount. Taking it with meals can help, though calcium citrate has the advantage of working with or without food—unlike some other forms.

Checking with a healthcare provider beats buying on autopilot. Lab tests, diet reviews, even a conversation about habits can point the way. No single dose fits all. The goal sticks to building and protecting healthy bones, not just hitting a number on a label.

Are there any side effects or risks associated with Calcium Citrate Anhydrous?

What Happens Beyond the Label?

It’s easy to assume a bottle of calcium citrate anhydrous just keeps bones strong and hearts ticking. Many doctors recommend it for folks who don’t get enough calcium from food. Supermarkets and pharmacies line shelves with these bottles, promising a simple fix for weak bones and muscle cramps. Still, people ask: are there real side effects or risks tied to this supplement?

Digestive Issues: A Common Complaint

Over the years, I’ve met plenty of folks who popped calcium pills to try to ease early osteoporosis. Pretty soon, some of them complained about constipation or gas. These aren’t rare reactions. Science backs this up—a report from the International Osteoporosis Foundation shows increased calcium can slow down your gut, making you uncomfortable.

It gets trickier for seniors. Older adults already deal with digestive changes, and even a modest daily dose sometimes brings on bloating or hard stools. Drinking more water and adding fiber sometimes helps, but folks often have to adjust routines or cut back completely.

Kidney Stones: Not Just a Rumor

Family history taught me to respect kidney stones. My dad spent some tough nights in the ER because of them. Doctors explained that extra calcium—especially if you don’t drink enough water—can encourage stones to form, particularly if you've had them before. Research from Harvard backs this up: calcium supplements can nudge your risk higher if you’re prone to stones, especially if you pair them with high amounts of vitamin D.

Long-Term Heart Health

Cardiologists raised red flags years ago about some older studies suggesting links between high-dose calcium supplements (over 1,000 mg per day) and calcification in arteries. Though more recent reviews give a mixed picture, experts like those at the Mayo Clinic still advise moderation. Risk rises if you already live with high blood pressure or have a family history of heart disease.

Calcium Interactions and Medication Trouble

A few neighbors down the hall at my old place—living with thyroid issues—ran into trouble taking calcium citrate anhydrous close to their thyroid medication. The supplement blocks absorption, making prescriptions less effective. Drugs for osteoporosis, antibiotics, and even blood pressure pills work the same way. It doesn’t take much: just swallowing pills within a couple of hours of one another can mess things up.

Who Should Pause Before Taking Calcium Citrate Anhydrous?

Most people get by just fine with moderate calcium citrate anhydrous if they’re healthy and drink plenty of water. Still, those with chronic kidney disease, parathyroid disorders, or past kidney stones have special reasons to be careful. Diet does most of the heavy lifting for bone health, according to the NIH. Dairy, leafy greens, and fish with soft bones cover your daily baseline if you can eat them, and they carry less risk of overload.

How to Reduce the Risks

Too many people treat supplements like a shortcut. Before reaching for calcium citrate anhydrous, ask for a blood test—the results help show what you really need. Don’t self-prescribe. Talk out plans with a doctor or pharmacist, especially if you juggle several medications or have other health problems in the family. Check for small, regular doses instead of megadoses. Drink more water if you're supplementing and keep your meals balanced. Real food beats bottles almost every time.

Can Calcium Citrate Anhydrous be taken with other medications or supplements?

Navigating Everyday Health Choices

Walking down the supplement aisle at any big box store reveals just how much faith people put in vitamins and minerals. Calcium citrate anhydrous finds its way into the daily routine for a lot of reasons—chief among them, bone health, especially in older adults. But adding a new tablet to the mix doesn't happen in isolation. Many folks already take prescription medicines, keep up with other supplements, or have health concerns nudging them to be more careful. Taking calcium seems simple, but it’s worth letting reality step in.

Why the Mixing Matters

Medication timing and combinations turn out to be anything but straightforward. Calcium isn’t merely a bone builder; it acts like a gatekeeper in the gut, sharing the space where absorption happens with a lineup of other nutrients and drugs. For example, thyroid hormone pills, some osteoporosis medications, and certain antibiotics all show up on the list of drugs that may not work as well if taken right alongside calcium. Magnesium, iron, and zinc tend to fight for the same attention too. The evidence comes from pharmacology studies that measure how much of these drugs or minerals get into the bloodstream. With calcium hogging the spotlight in the digestive tract, less of the other guy crosses over, which matters when someone needs a steady, reliable dose.

Common Pairings That Deserve a Closer Look

Doctors see patients struggle with medication routines more often than most realize. In my own family, timing out supplements has turned into a low-key science experiment. Thyroid replacement therapy usually lands first thing in the morning, and missing that narrow window before breakfast or after calcium can make blood levels swing. Many women take calcium and iron, but the science says these two need space from each other—at least a couple of hours—if full absorption is the goal. Mixing calcium with prescription osteoporosis drugs like alendronate, or with antibiotics in the tetracycline or fluoroquinolone families, can dull each drug’s punch.

What Doctors and Pharmacists Recommend

Most people think one pill should work just fine with the rest. In reality, clinics and pharmacies field calls about interactions every week. The gold standard in practice is to space out doses: take thyroid hormone or osteoporosis drugs on an empty stomach, and let calcium citrate find its time a few hours later, usually with a meal. By following this plan, the gut avoids a traffic jam at the absorption gates. Pharmacists offer practical advice, often based on credible guidelines from journals, hospital protocols, and medical groups like the American Society of Health-System Pharmacists or the Endocrine Society.

Solutions That Actually Work Outside the Lab

Setting reminders, using pillboxes with time slots, and keeping a written schedule sound basic, but they help real people who handle multiple pills daily. Some patients keep a notebook—writing down what works and what triggers side effects or stomach upset. For those new to supplements, checking in with a healthcare professional before starting any routine prevents a lot of the headaches that come from drug-nutrient skirmishes. Online reputable sources, like MedlinePlus or the National Institutes of Health Office of Dietary Supplements, break down these interactions with details in plain language. Patient forums, though not always vetted, point out day-to-day struggles, adding context that can sometimes get lost in the clinic.

Looking Out for the Best Outcomes

Calcium citrate anhydrous brings real benefits, but fitting it into an already busy medication lineup means thinking through possible conflicts and practical fixes. The risks rarely come from the calcium itself—it’s really about the timing. Checking labels, talking openly with healthcare providers, and paying attention to guidance works better than assuming the body will sort everything out on its own. The details make the difference in bone health and long-term health plans.

Calcium Citrate Anhydrous
Names
Preferred IUPAC name Calcium 2-hydroxypropane-1,2,3-tricarboxylate
Other names Calcium Citrate
Anhydrous Calcium Citrate
Tricalcium Citrate
Citrate of Lime
Pronunciation /ˈkæl.si.əm ˈsɪ.treɪt ænˈhaɪ.drəs/
Preferred IUPAC name Calcium 2-hydroxypropane-1,2,3-tricarboxylate
Other names Calcium citrate
Citrate of lime
Lime citrate
Anhydrous calcium citrate
Pronunciation /ˈkæl.si.əm ˈsɪ.treɪt ænˈhaɪ.drəs/
Identifiers
CAS Number 7693-13-2
Beilstein Reference 1737333
ChEBI CHEBI:31357
ChEMBL CHEMBL1201565
ChemSpider 21511499
DrugBank DB11092
ECHA InfoCard 03d08130-84df-473c-a4b6-2fcbec24c34f
EC Number 5758-44-9
Gmelin Reference 35868
KEGG C07084
MeSH D017986
PubChem CID 159393
RTECS number FF2625000
UNII 1K8OJ1RN5U
UN number 3077
CAS Number 813-94-5
Beilstein Reference 3588745
ChEBI CHEBI:610370
ChEMBL CHEMBL1203632
ChemSpider 13943322
DrugBank DB11092
ECHA InfoCard 100.028.291
EC Number 211-072-3
Gmelin Reference 24741
KEGG C00642
MeSH D018474
PubChem CID 159748
RTECS number FF8050000
UNII 1KAT973YS3
UN number UN-number not assigned
Properties
Chemical formula Ca₃(C₆H₅O₇)₂
Molar mass 498.43 g/mol
Appearance White powder
Odor Odorless
Density 2.4 g/cm³
Solubility in water Slightly soluble in water
log P -1.0
Vapor pressure Negligible
Acidity (pKa) 3.5
Basicity (pKb) 7.5
Magnetic susceptibility (χ) Diamagnetic
Dipole moment 1.44 D
Chemical formula Ca₃(C₆H₅O₇)₂
Molar mass 498.43 g/mol
Appearance White powder
Odor Odorless
Density 2.41 g/cm³
Solubility in water Slightly soluble in water
log P -1.5
Vapor pressure Negligible
Acidity (pKa) 3.1
Basicity (pKb) 8.48
Magnetic susceptibility (χ) Diamagnetic
Dipole moment 0 D
Thermochemistry
Std molar entropy (S⦵298) 357.2 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -2314 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -3221 kJ/mol
Std molar entropy (S⦵298) 427.1 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -2077.0 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -2344 kJ/mol
Pharmacology
ATC code A12AA04
ATC code A12AA07
Hazards
GHS labelling GHS07, GHS08
Pictograms GHS07
Signal word Warning
Hazard statements No hazard statement.
Precautionary statements Precautionary statements: P264, P270
NFPA 704 (fire diamond) 1-0-0
Lethal dose or concentration LD50 Oral - Rat - > 2,000 mg/kg
LD50 (median dose) LD50 (median dose): Oral rat LD50 > 2,000 mg/kg
NIOSH EW2550000
PEL (Permissible) 15 mg/m3
REL (Recommended) 1000 - 2500 mg/day
Main hazards May cause respiratory irritation. May cause eye irritation. May cause skin irritation.
GHS labelling GHS07, Warning, H319, P264, P280, P305+P351+P338, P337+P313
Pictograms GHS07
Signal word Warning
Hazard statements May cause respiratory irritation.
Precautionary statements P264, P270, P273, P301+P312, P330, P501
NFPA 704 (fire diamond) Health: 1, Flammability: 0, Instability: 0, Special: -
Lethal dose or concentration LD50 oral rat 8,040 mg/kg
LD50 (median dose) LD50 (median dose): Oral, rat: 2,940 mg/kg
NIOSH EW298
PEL (Permissible) 15 mg/m³
REL (Recommended) 1200 mg Ca/day
Related compounds
Related compounds Calcium Citrate Tetrahydrate
Citric Acid
Calcium Carbonate
Calcium Gluconate
Calcium Lactate
Related compounds Calcium citrate
Tricalcium dicitrate
Citric acid
Calcium carbonate
Calcium chloride