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Brilliant Blue: History, Makeup, and the Road Ahead

Historical Development

Brilliant Blue roots reach back to the industrial age, where color innovation kicked into high gear right alongside synthetic dyes for fabric and food. As efforts to replace risky natural pigments gathered pace, chemical giants raced to develop stable compounds that could survive scrutiny and stick around on store shelves. Brilliant Blue came out of the flurry of synthetic dye discoveries in the early 1900s, around the same time big changes shaped agriculture, textiles, and pharmaceuticals. Even before food regulations set the tone, demand for reliable, striking colorants pushed chemists to refine formulas. Over the decades, regulatory agencies like the FDA and EU committees reviewed safety, sparking both review and efficiency drives in the dye’s production. As a result, Brilliant Blue became a staple ingredient, enduring bans, debates, and renewed approvals tied directly to new toxicology data or production standards.

Product Overview

Known as Brilliant Blue FCF or FD&C Blue No. 1 in North America, this dye stands out on ingredient lists everywhere. Its eye-grabbing electric blue shade remains popular in candy, beverages, pharmaceuticals, and even biotech research. Manufacturers supply it mostly as a fine powder or ready-to-use granules that dissolve in water nearly instantly. Each batch sees careful quality control, documented by batch numbers and certifications that assure buyers it passes food or pharma use standards. Multinational suppliers tout decades of scale-up knowledge, shipping tons each year to food factories, science labs, and hospitals.

Physical & Chemical Properties

Brilliant Blue’s color comes from its aromatic ring system, loaded with sulfonic acid groups for water solubility. It appears as a dark, greenish-blue to purple powder but transforms into a fierce blue once dissolved. Light fastness keeps it from fading in most applications unless exposed to strong oxidants or sunlight for too long. In the lab, its chemical stability speaks volumes; the dye keeps its shade in neutral and slightly alkaline solutions but weakens in harsh acids. Melting doesn’t matter much, as the product decomposes before boiling, a fact that matters less for food chemists but more for process engineers considering technical hazards.

Technical Specifications & Labeling

Regulators set strict purity minimums for Brilliant Blue destined for human consumption, with food-grade batches clocking in at over 85% dye content, few insoluble materials, and near-zero heavy metals. Labels must read “Brilliant Blue FCF” in the EU or “FD&C Blue No. 1” in the US, and standards demand full ingredient disclosure even for products using the color as a tracer. Most suppliers ship in tamper-proof, food contact material-compliant drums or bottles, and safety data sheets accompany shipments for factory workers. Expiry dates on bulk containers build trust, as does clear lot traceability for quick recalls.

Preparation Method

Brilliant Blue’s synthesis follows a classic pathway: a condensation reaction between aromatic sulfonic acids and aniline under closely controlled temperatures, then oxidation to set the main chromophore. Purification typically involves several washing and recrystallization steps to remove trace metallic or organic impurities, resulting in a pure, water-soluble powder. The entire process requires constant monitoring, as deviations in temperature or reagent quality can alter dye strength or introduce byproducts that need further cleaning. Factories keep tight records for each stage, knowing every tweak can show up in a food chemist’s analytical test.

Chemical Reactions & Modifications

Beyond its standard state, chemists have tweaked Brilliant Blue for better performance in scientific assays. Introducing different counterions or minor side chains can influence solubility, flow through gels, or signal strength in diagnostic kits. Although not common in food use, these modifications extend its shelf life, tune absorption wavelengths, or adjust behavior during chromatography. Under oxidative stress, the dye can lose intensity, a trait that sometimes proves useful for tracking reagent life in biochemical research. Real-world adjustments often demand a trade-off: better performance for specific needs, balanced with regulatory rules and cost constraints.

Synonyms & Product Names

Retailers and manufacturers often refer to Brilliant Blue by a list of recognized names: FD&C Blue No. 1, Acid Blue 9, E133, CI Food Blue 2, or Patent Blue F. In pharmaceuticals, the same dye might appear as simply Blue 1. These names reflect local law, product labeling rules, or even cultural trends. Although the chemistry remains the same, the code that appears on a snack wrapper in Paris won’t match the name used in a research journal in Michigan. Having a cross-reference table close at hand proves wise for anyone working across borders or product lines.

Safety & Operational Standards

Factories handling Brilliant Blue keep strict protocols to minimize exposure risks, as powder can act as a mild irritant to skin or the lungs. Large-scale production involves dust containment, air filtration, and routine site audits. Workers wear gloves and sometimes respirators when blending or sampling. Finished products headed for food or drug use undergo thorough inspection for unwanted impurities, especially heavy metals and solvent residues. Facilities follow ISO or GMP standards, enforced through random third-party audits and in-house quality teams who face serious consequences for breaches. Site operators track environmental waste streams, knowing both wastewater color and trace contaminants fall under local discharge laws.

Application Area

Brilliant Blue’s uses stretch surprisingly far. Food processors add it to soft drinks, ice cream, jellies, and breakfast cereals for that unmistakable pop. Pharmaceutical firms use the dye as a coating for pills, helping people identify doses by shade. In the medical world, doctors inject it during some surgeries to check tissue blood flow or spot leaks. Research labs love the dye for staining gels in protein analysis, as it highlights differences at the molecular level. Even aquarium hobbyists turn to it to create more vibrant tank displays, trusting its longstanding track record as a safe choice for both humans and animals.

Research & Development

Recent years have seen a shift toward pinpointing any health concerns tied to synthetic dyes, with Brilliant Blue often under the microscope due to increased public scrutiny. Academic studies, funded by both industry and government, explore both acute and chronic effects from dietary exposure. Newer research looks at metabolism, tracking how the dye breaks down in the body and how much crosses into the bloodstream versus being excreted. Big pushes also aim to improve both synthesis and waste treatment, targeting more efficient, less polluting production. Companies partner with universities, examining tweaks to the molecule that enable expanded use in high-tech medical imaging or biochemical sensors. Some projects go beyond health and manufacturing, studying ways to swap out fossil-derived ingredients for renewable stock, aligning with broader sustainability trends.

Toxicity Research

Toxicologists run constant tests to spot hidden dangers, especially as parents question food coloring in children’s snacks. Although authorities like the FDA and EFSA set firm, science-backed limits, each new study feeds into the debate. At current approved levels, Brilliant Blue rarely causes allergic responses or toxicity, even with lifelong daily exposure. Some animal tests suggest high doses can strain certain organs, which keeps regulators vigilant about cumulative intake. Surveillance scans big eating studies for links to behavioral or metabolic shifts, and new regulatory reviews emerge as soon as new data arrives. The steady stream of transparent findings helps reassure the public and keep standards modern.

Future Prospects

The story of Brilliant Blue keeps evolving. Consumer pressure grows for clearer labeling and fewer synthetic ingredients, driving research into alternatives sourced from plants or microbes. Some companies work on hybrid dyes, blending modern chemistry with botanicals to keep color vivid yet label friendly. Improvements in industrial synthesis might lower both environmental footprint and production cost, making the dye more sustainable for the future. In specialized fields – from regenerative medicine to next-generation sensors – custom modifications already open up new value streams, showing how a century-old compound can still offer fresh possibilities. Investors and researchers alike keep watch, knowing regulations and public sentiment can reshape demand overnight, while science keeps finding new doors for this brilliant old dye.




What is Brilliant Blue used for?

A Blue That Shows Up in Surprising Places

Brilliant Blue has a way of turning up in day-to-day life more often than most folks assume. Walk through any supermarket and the colorful snacks or drinks line the shelves, many of them shining with that distinctive electric blue. Kids’ cereals, sports drinks, even cake frostings often use it. That bright pop doesn’t just grab attention; it shapes how products stand out in busy aisles.

From Food to Pharma: Roles Beyond Sweets

Being a synthetic dye, this colorant isn’t just stuck in the candy aisle. Over the years, Brilliant Blue—sometimes listed as FD&C Blue No. 1—has found its way into all sorts of other industries. Medicines, toothpaste, and even some cosmetics use this dye to look appealing or to signal a certain flavor or function. Open a tube of blue gel toothpaste or check out some cold and allergy pills; odds are, this blue is working in the background.

Hospitals and research labs also rely on this dye, but for more practical reasons. Surgeons sometimes use a variation called Brilliant Blue FCF during procedures to help visualize tissues. Scientists in biology labs often use it in protein studies since it helps track and analyze results that would otherwise be invisible.

Health Questions: A Closer Look at Safety

The reason for adding Brilliant Blue to all those foods and products comes down to marketing and readability, but there’s always the health question. Over decades, agencies like the FDA in the US and EFSA in Europe have evaluated its safety. Evidence collected so far shows that, in moderate amounts, the dye is considered safe for most people. Some rare allergy cases do pop up, especially for those with certain health conditions, but those stories are few.

The case of Brilliant Blue points to a bigger issue in modern diets. Processed foods—especially those aimed at kids—tend to load up on synthetic dyes. Scientists have debated for a long time whether these colorants might affect attention or behavior in children. Some small studies hinted at a connection, but scale and quality haven’t convinced everyone. The general medical community does not warn the average family away from products dyed with Brilliant Blue in ordinary amounts, yet continued research never hurts.

What Should Change?

People don’t always choose foods based only on health. Color pulls in the eye, makes food fun, and can even send signals about flavor. Still, if companies rely less on synthetic hues like Brilliant Blue and focus more on natural alternatives, the whole package might become a bit healthier. Some companies already offer product lines without artificial colors, using vegetable sources instead.

Clearer packages and more detailed labeling mean people can avoid synthetic dyes if they want. Governments and watchdog groups should keep pushing for transparency so families know what’s inside the box or bottle. Schools and hospitals, often a first line for nutrition in children and vulnerable groups, can help by reducing the use of dyed foods on their menus.

A Colorful Decision for Every Consumer

Brilliant Blue makes more than just products stand out. It serves as a reminder that with every colorful bite, we take in a piece of modern food science. Looking out for trusted sources of information and reading ingredient lists with care matter, especially once kids or people with health concerns are in the picture. Through pushing for more natural dyes, improved oversight, and honest labeling, everyone gets a shot at making choices that work for their families and their bodies.

Is Brilliant Blue safe for consumption?

Understanding Brilliant Blue in Your Food

Brilliant Blue, better known on ingredient labels as Blue No. 1 or E133, shows up in everything from candy and soft drinks to yogurt and even some medicines. Catchy colors draw eyes, especially for kids, but since the world caught on to the potential downsides of artificial additives, concerns over every ingredient have grown. People check labels and wonder if food dyes like Brilliant Blue hold up to scrutiny or if they slip by because they’re familiar.

The Science Behind the Color

Brilliant Blue shows up in labs and regulations worldwide. Food safety agencies in the United States, Europe, Japan, and Australia have all reviewed the dye. Research has found low toxicity at the levels people eat. The U.S. Food and Drug Administration has set an acceptable daily intake of 12 mg per kilogram of body weight—much more than anyone gets from a blue sports drink or lollipop. The European Food Safety Authority ran a thorough review in 2010 and kept the dye on the approved list. The main conclusion: consumers using these products as part of a balanced diet face minimal risk from ordinary intake.

Sensitivity Isn’t the Same for Everyone

Although scientists agree about general safety for healthy people, there’s a twist. Some people react to artificial dyes, including Brilliant Blue. Folks who struggle with allergies, asthma, or certain health conditions sometimes report hives or itching after eating products colored with synthetic dyes. Hospitals have used the dye for tracking fluids inside the body, and those rare patients have occasionally experienced serious allergic reactions. For most, these symptoms don’t appear, but doctors recommend caution for anyone with a history of colorant sensitivity.

The Broader Context: Hyperactivity and Food Colors

Studies pop up from time to time linking food dyes—Brilliant Blue included—to hyperactivity in children. The evidence isn’t crystal clear. Most large studies don’t show a strong tie, yet some research points to small but real effects in certain sensitive kids. For parents, the safest choice is to watch for patterns: if a child seems to bounce off the walls after colorful candies, try a week with plain-looking snacks and see if the difference jumps out. Some experts question why colorful additives stick around with so many safe natural coloring options on the market. It comes down to cost, stability, and shelf life—natural blue sources are rare and fade faster.

Looking Ahead: What Should Change?

Choices about food additives sit between risk, benefit, and trust. Regulators keep track of new studies and make changes if evidence demands it. For those who still hesitate, it pays to read labels and pick products with simple ingredient lists. Several brands now cater to shoppers asking for alternatives, using colors from spirulina, purple carrots, or blueberries. I’ve watched local stores carry more of these options every year, and families react well to having a say over what goes into their meals. Changes in tastes and more open ingredient information make it easier for us to decide for ourselves. Staying informed and speaking up with questions pushes producers toward options that work for everyone.

What are the ingredients in Brilliant Blue?

Understanding Brilliant Blue’s Recipe

Brilliant Blue, known to many as FD&C Blue No. 1 or E133, turns up in sodas, popsicles, candies, and even some pharmaceuticals. Plenty of us have seen the wild colors it brings to party drinks or festive frosting. Behind the scenes, you’ll find several specific ingredients shaping that bright blue experience.

Main Chemical Component

At its core, Brilliant Blue starts with its main molecule: disodium salt of ethyl (4-([4-(N-ethyl-3-sulfophenyl)methylamino]phenyl)(2-sulfonatophenyl)methylene)-2,5-cyclohexadien-1-ylidene}(N-ethyl-3-sulfophenyl)methylammonium hydroxide. People rarely use its full scientific name, but this compound brings the distinct color. The structure sits on a base of aromatic rings marked with sulfonic acid groups and other side chains, giving it the vivid shade and letting it dissolve easily in water. This chemistry allows food makers to get deep blue hues without a chalky aftertaste.

Extra Ingredients Supporting the Color

Manufacturers produce Brilliant Blue by combining simple raw materials—like aniline, benzaldehyde, and sulfuric acid—under industrial conditions. These chemicals drive a process called sulfonation, followed by a neutralization step that brings in sodium salts. The sodium salts stabilize the dye, helping it blend smooth into foods and drinks. It’s not just food and beverages that benefit. Certain medications, makeup, and bath bombs get their playful look from the same coloring solution.

Additives and Fillers in Commercial Colors

Brilliant Blue powders and liquids run into other practical needs, so companies toss in anti-caking agents such as sodium sulfate or sodium chloride. These stop the color from clumping up in the canisters before it reaches factories or kitchens. Some liquid forms contain a little propylene glycol, which keeps the color stable while traveling through hot or cold environments. Occasionally, preservatives like sodium benzoate stop the growth of mold and bacteria inside bulk containers.

Health Questions — What Science Tells Us

Brilliant Blue isn’t just pretty. Studies have explored health impacts too. For most people, it passes through the body with no changes and exits quickly. Tests on its toxicity and long-term presence have let safety agencies around the world approve it up to certain levels in foods. In rare cases, some folks with allergies or specific digestive issues react to synthetic dyes, including this one. A small number of reports link synthetic blues to hyperactivity behaviors in sensitive kids. For the general public, doses in standard food servings fall below levels shown to cause problems.

The flip side is labeling and transparency. People like to know what they’re eating. Right now, labeling laws in places like the US or EU require listing “Brilliant Blue FCF” or its E-number E133. The details on packaging help shoppers who want to avoid it.

Looking for Alternatives

Some food companies now look to natural options, with blue made from spirulina or butterfly pea flowers. These don’t always give the punchy color or shelf life of synthetic dyes, but the shift matches rising demand for simpler ingredient lists. More research can help close the performance gap between natural colors and synthetic dyes like Brilliant Blue.

Shoppers have more power than ever to shape what ends up in their food. Knowing what’s really in something as basic as a blue candy or a sports drink, and pushing for honest labeling, leads to better choices from everyone—industry, regulators, and regular people alike.

Does Brilliant Blue cause any side effects?

Stuff Hiding in Plain Sight

Plenty of people enjoy snacks with bold, vibrant colors without thinking much about what gives chips, soda, or gummies that eye-catching look. Brilliant Blue, sometimes called Blue No. 1, draws a lot of attention for this reason. For years, I looked past ingredients lists, trusting that anything in a grocery aisle passed the safety test. Turns out, even FDA-approved stuff can have a bigger story behind it.

Digging into Side Effects

Brilliant Blue is allowed in the US and much of the world, but some researchers keep their eyebrows raised. It’s true that most folks can gobble blue-frosted cupcakes and never feel odd. Still, a handful of people do react badly. There’s no shortage of medical case reports describing allergic responses—itchiness, rashes, upset stomach—linked to this dye. These symptoms don’t hit everyone, and most people who eat a standard portion of colored snacks notice nothing at all. But if you ever felt off after eating colorful treats, it might not be just a sugar rush to blame.

In rare instances, especially in large doses, some people have had more serious reactions. A well-known case involved a patient with asthma who experienced shock after a dose of medication laced with Brilliant Blue. While stories like this come from extreme cases, and the average bite of blue cereal contains far less dye, the risk for people with dye sensitivities doesn’t vanish.

What Scientists Are Learning

Research keeps adding layers to this story. Animal experiments suggest high doses may harm nerve cells, but scientists haven’t found strong evidence these problems show up at the usual levels seen in a normal diet. Long-term exposure hasn’t been shown to cause cancer in humans, but some mouse studies do show changes in cell growth. Nothing beats decades of follow-up in real people, so these small animal studies hold some weight but don’t seal the deal.

Brilliant Blue isn’t just in food. Hospitals use a purified version in some medical procedures, like to stain tissues, and mistakes there can trigger blood pressure changes or kidney effects. It’s rare, more of a hospital risk than a grocery store one, but it’s on the radar in medicine.

Why Paying Attention Still Matters

People who stick to processed foods tend to eat more dyes overall. Children come into focus; families rush from breakfast cereals to sports drinks with every color of the rainbow, and kids who react to one dye are more likely to react to others. Even with official green lights from food safety authorities, allergic folks and parents of sensitive kids stay cautious, and reports trickle in about discomfort tied to Brilliant Blue and other dyes.

Europe, Australia, and a few other places have nudged companies to add warnings or rethink recipes. In my own kitchen, I favor labels with fewer ingredients—less artificial stuff means fewer questions about what’s hiding behind the flavor and fun colors. There’s no panic here, but some extra awareness never hurts. For people itching, breaking out, or feeling ill after a rainbow treat, seeking medical advice and checking labels makes a world of difference.

Where can I buy Brilliant Blue?

Understanding Brilliant Blue

Brilliant Blue, sometimes called FD&C Blue No. 1, shows up in everything from sports drinks to ice pops. This synthetic dye gives foods and drinks a bright electric color that grabs your attention. People remember seeing that vibrant blue when they were kids. It’s not just for food, either — labs use it and textile makers love its bold shade.

Where People Look for Brilliant Blue

Plenty of folks type “where can I buy Brilliant Blue” on Google because they need the color for school experiments, art projects, homemade recipes, or research. But the answer depends on why you want it. Grocery stores sometimes carry food-grade versions for baking. Specialty baking shops or hobby stores usually carry small containers meant for frosting or cake decorating. You’ll also spot it as a powdered dye or gel color on big online marketplaces, like Amazon or Walmart. Just reading the ingredient list carefully is important to avoid mixing it up with similar dyes, such as Blue No. 2, which gives a different shade and sometimes works differently in recipes.

The Food-Grade and Industrial Divide

Not all Brilliant Blue dyes match up. Food-grade products meet strict regulations—they get tested for purity, and buyers can check labels for certification numbers or seals from the FDA. These products keep meals safer, especially since some folks can be sensitive to synthetic dyes. If you’re using the dye on cakes, desserts, or for a science fair where kids might handle the material, stick to food-safe options. For art or textiles, industrial grades get sold in bulk packages from chemical suppliers. These versions don’t always pass the same safety tests as food-grade dyes and often come with warnings to avoid swallowing or getting them on skin.

Regulations and Health Considerations

Food additives raise concerns. The European Food Safety Authority and the FDA have tested Brilliant Blue for years. People talk about allergies and links to hyperactivity. Most studies show that it’s safe in small amounts, but critics argue there should be more labeling and limits, especially in foods for young children. Buying from legit retailers matters—food dye from reputable stores or verified online sellers means fewer risks of contamination or unsafe substitutes.

Solutions and What Buyers Can Do

Shoppers have options. If you want total peace of mind, track down stores that label products as “edible” or “food-safe” with clear batch numbers. Consider researching suppliers—online reviews, certificates, and testing results tell you a lot. Reach out to customer service for more facts if you’re buying in bulk. For cautious families, natural colors like spirulina or butterfly pea flower give a blue hue without artificial dyes—great for those with allergies or kids sensitive to artificial colors. Scientists, teachers, and crafters with specific needs can look for specialty chemical suppliers, but these usually require proof that you’re using it for legitimate scientific or technical work.

Why Sourcing Brilliant Blue Matters

Traceability and safety can’t be brushed aside. Imported dyes sometimes skip safety rules. A few cases of mislabeled colors linked to health scares have popped up in news headlines. Personal experience taught me to avoid no-name brands and double check the packaging, especially for kids’ projects. Parents and teachers shopping for dye feel better knowing it won’t end up causing more harm than fun.

Brilliant Blue
Names
Preferred IUPAC name Disodium 3-{[N-ethyl-N-(3-sulfophenyl)amino]carbonyl}-4-[(4-ethyl-3-sulfophenyl)(2-sulfonatophenyl)methylamino]naphthalene-1-sulfonate
Other names CI 42090
FD&C Blue No. 1
Acid Blue 9
E133
Food Blue 2
Blue 1 Lake
Brilliant Blue FCF
Pronunciation /ˈbrɪliənt bluː/
Preferred IUPAC name disodium 3,3'-[(E)-(4-((E)-4-anilinophenyl)diazenyl)bis(5-methyl-4-oxo-2,5-dihydrofuran-3-ylidene)]bis(1-amino-4-oxonaphthalene-2,7-disulfonate)
Other names Acid Blue 9
FD&C Blue No. 1
E133
C.I. 42090
Brilliant Blue FCF
Pronunciation /ˈbrɪl.jənt bluː/
Identifiers
CAS Number 3844-45-9
Beilstein Reference 2253107
ChEBI CHEBI:61117
ChEMBL CHEMBL2103838
ChemSpider 20867
DrugBank DB11219
ECHA InfoCard ECHA InfoCard: 100_032_814
EC Number 133-37-9
Gmelin Reference 87848
KEGG C06636
MeSH D030187
PubChem CID 19700
RTECS number BX5826000
UNII 3M9087850O
UN number UN3077
CAS Number 3844-45-9
Beilstein Reference 1367483
ChEBI CHEBI:5908
ChEMBL CHEMBL2103839
ChemSpider 15920
DrugBank DB11221
ECHA InfoCard 100.015.901
EC Number E133
Gmelin Reference 730
KEGG C42075
MeSH D016677
PubChem CID 19700
RTECS number SC2975000
UNII DMQ3XUV48I
UN number UN3077
Properties
Chemical formula C37H34N2Na2O9S3
Molar mass 792.84 g/mol
Appearance Blue powder
Odor Odorless
Density 0.73 g/cm³
Solubility in water Soluble in water
log P -2.52
Acidity (pKa) 7.00
Basicity (pKb) 6.42
Magnetic susceptibility (χ) -24.0e-6 cm³/mol
Refractive index (nD) 1.542
Viscosity Medium viscous
Dipole moment 2.52 D
Chemical formula C37H34N2Na2O9S3
Molar mass 792.84 g/mol
Appearance Appearance: Blue powder
Odor Odorless
Density 0.83 g/cm³
Solubility in water Soluble in water
log P -2.36
Vapor pressure Negligible
Acidity (pKa) 7.00
Basicity (pKb) 7.52
Magnetic susceptibility (χ) -23.0e-6 cm³/mol
Refractive index (nD) 1.53
Viscosity 25-35 sec (Ford Cup B/25°C)
Dipole moment 3.47 D
Thermochemistry
Std molar entropy (S⦵298) 356.0 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -706.1 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -2294 kJ/mol
Std molar entropy (S⦵298) 340.6 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) −1,677 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -7914 kJ/mol
Pharmacology
ATC code A11GAણ
ATC code V04CX01
Hazards
Main hazards May cause eye, skin, and respiratory tract irritation.
GHS labelling GHS07, GHS08
Pictograms GHS07, GHS09
Signal word Warning
Hazard statements H319: Causes serious eye irritation.
Precautionary statements P264; P270; P273; P301+P312; P305+P351+P338; P330; P501
Flash point >100 °C
Lethal dose or concentration LD₅₀ (oral, rat): 2,000 mg/kg
LD50 (median dose) > 2000 mg/kg (rat, oral)
NIOSH TC-84A-9214
PEL (Permissible) 10 mg/m³
REL (Recommended) 30 mg/L
IDLH (Immediate danger) Not established
Main hazards Harmful if swallowed. May cause irritation to the eyes, skin, and respiratory tract.
GHS labelling GHS07, GHS09
Pictograms GHS07,GHS09
Signal word Warning
Hazard statements H319: Causes serious eye irritation.
Precautionary statements P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P333+P313, P337+P313, P362+P364
Flash point >100 °C
Autoignition temperature 385°C
Lethal dose or concentration LD₅₀ (oral, rat): 2,000 mg/kg
LD50 (median dose) > 2000 mg/kg (rat, oral)
NIOSH N95
PEL (Permissible) 10 mg/m³
REL (Recommended) 60 mg/kg
Related compounds
Related compounds Patent Blue
Indigo carmine
Erioglaucine
Quinoline Yellow
Related compounds Patent Blue V
Indigo carmine
Coomassie brilliant blue
Acid blue 9
FD&C Blue No. 1