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Product Name: Bile Acid
Chemical Family: Steroid Acids
Chemical Formula: C24H40O5 (generalized, varies by specific bile acid)
Common Names: Cholic Acid, Deoxycholic Acid, Chenodeoxycholic Acid
Recommended Use: Research, pharmaceutical applications, biochemical analysis
Manufacturer/Supplier: Refer to sourcing lab or supplier
Contact Information: Available through supplier documentation or lab protocol
Emergency Phone: Emergency services (local) or Poison Control Center
Synonyms: See specific type of bile acid for alternative names
GHS Classification: Not classified as hazardous according to current legislation for laboratory use; some forms may cause health risks with improper exposure
Hazard Statements: May cause irritation to eyes, skin, respiratory tract upon significant contact
Pictograms: Not typically required
Signal Word: None shown for laboratory grades
Precautionary Statements: Use barriers like gloves, goggles; avoid ingestion or inhalation; handle in well-ventilated areas
Other Hazards: Fine powders may cause dust which can irritate mucous membranes; no major long-term health reports in typical laboratory settings
Chronic Effects: No significant chronic toxicity identified in basic lab exposure models; large scale or chronic exposure not well studied
Chemical Identity: Bile Acid(s)
CAS Numbers: Cholic Acid 81-25-4, Deoxycholic Acid 83-44-3, Chenodeoxycholic Acid 474-25-9
Purity: Usually over 95% depending on supplier
Impurities: Water, possible trace steroid contaminants from isolation
Additional Components: None expected in research-grade materials
Eye Contact: Rinse with plenty of water for several minutes; remove contact lenses if possible and continue rinsing; seek medical attention with ongoing discomfort
Skin Contact: Wash contact area with water and soap; take off contaminated clothing; medical attention if irritation persists
Inhalation: Move person into fresh air; support breathing; consult physician if symptoms develop
Ingestion: Rinse mouth; do not induce vomiting; seek medical help if large quantities ingested
General Notes: Symptomatic treatment based on clinical judgment after exposure
Suitable Extinguishing Media: Carbon dioxide, dry chemical, or foam extinguishers
Unsuitable Extinguishing Media: None particularly noted, though water spray may spread powders
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, trace hazardous organic vapors possible
Firefighting Methods: Wear self-contained breathing apparatus and full protective equipment
Other Fire Hazards: Product itself not highly flammable but packaging may burn
Personal Protection: Gloves, lab coat, dust mask, and safety goggles
Environmental Precautions: Avoid discharge into drains or waterways
Spill Cleanup Methods: Sweep up carefully without creating dust; collect in appropriate containers for disposal; clean surface with water to remove residues; ventilate area
Decontamination: Soap and water, avoid aggressive chemicals on laboratory surfaces
Handling: Avoid inhalation, ingestion, and contact with skin or eyes; work in a ventilated area; use good laboratory hygiene
Storage: Keep container tightly closed; store in cool, dry, well-ventilated space; separate from strong acids, bases, and oxidizing agents; clearly label all containers
Specific Incompatibilities: Strong oxidants, acids, bases; moisture may degrade stability
Hygiene Measures: Wash hands after handling; do not eat, drink, or smoke in work area
Occupational Exposure Limits: No occupational exposure limits established; minimize exposure by engineering controls
Engineering Controls: Fume hood, effective room ventilation
Personal Protective Equipment: Gloves (nitrile or latex), safety goggles, lab coat, respiratory protection in case of dust generation
Environmental Exposure Controls: Prevent release to environment; proper waste container usage
Appearance: White to off-white solid or powder
Odor: Odorless or faint organic odor
pH: Slightly acidic to neutral (1% solution 5–7)
Melting Point: Typically 195–203 °C (varies by type)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: High in ethanol, low in water (depends on specific bile acid form)
Vapor Pressure: Not measurable at room temperature
Other Data: Stable under normal laboratory conditions
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Unreactive under normal conditions
Possible Hazardous Reactions: Reacts with strong acids or oxidizing agents
Decomposition Products: Carbon oxides, organic fragments upon combustion or thermal decomposition
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: Mild irritation to skin, eyes, respiratory tract; high doses may cause gastrointestinal upset
Chronic Effects: Not well documented; animal studies show no major risk at typical lab exposure
Target Organs: May irritate mucous membranes
Carcinogenicity: Not classified as carcinogen
Mutagenicity/Teratogenicity: No evidence observed in standard research concentrations
Toxicity Data: LD50 (oral, rat) varies by specific bile acid, generally high (>1g/kg)
Aquatic Toxicity: Low toxicity to aquatic organisms at concentrations expected in spills; large releases could affect water quality
Persistence and Degradability: Biodegradable under normal conditions
Bioaccumulative Potential: Unlikely; metabolized by environmental microbes
Mobility in Soil: Low; slightly water soluble, binds to organic matter
Other Adverse Effects: Not expected under normal laboratory usage and disposal procedures
Disposal Methods: Dispose of in accordance with local/regional/national/international regulation; unused material to chemical waste stream, not household waste
Packaging Disposal: Contaminated containers handled as hazardous laboratory waste
Cleaning of Residues: Rinse equipment and surfaces thoroughly, collect rinsate for chemical disposal
Special Precautions: Avoid entry into drains, soil, and surface waters
UN Number: Not regulated
Transport Hazard Class: None assigned under conventional UN regulations
Packing Group: Not applicable
Labeling Requirements: Laboratory and research samples typically do not require hazard labeling for transport
Special Provisions: Transport in sealed containers as per chemical sample protocols
Labeling: Not considered hazardous for labeling under current chemical regulations in US (OSHA), EU (CLP/GHS), or equivalent standards
Inventory Status: USA TSCA – listed for some bile acids; REACH – not considered hazardous for registered uses
Other Regulations: No specific restrictions for laboratory and research quantities
Occupational Health: Adherence to general chemical safety guidelines for research materials
Additional Information: National and international guidelines may evolve; always check latest regulations for updates
