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Product Name: Bifidobacterium brevis
Synonyms: None assigned
Recommended Use: Probiotics, nutritional supplements, food additives, scientific research
Supplier: Manufacturer and supplier information required from source—address, emergency contact phone
Chemical Formula: Not applicable (microbial preparation)
CAS Number: 68038-65-3
Relevant Identified Uses: Intended for use in food, supplements, pharmaceuticals, and laboratory research
Distributor Contact: Specified by distributing company, reference technical support contact for emergencies
Classification: Non-hazardous biological material under OSHA 29 CFR 1910.1200; not classified as hazardous for transport or environmental purposes
Label Elements: Signal word: None; Pictogram: None; Hazard Statement: Not considered hazardous under GHS
Potential Health Effects: Minimal risk, but may irritate respiratory system in sensitive individuals; accidental ingestion in healthy persons considered low-risk; underlying medical conditions may elevate risk with immune-compromised populations
Precautionary Statements: Avoid inhalation of dust; wash hands after handling; use in well-ventilated areas to reduce respiratory exposure risks
Target Organs: None known for healthy adults; those with allergies or respiratory sensitivities should use care
Emergency Overview: No acute hazards; long-term data on opportunistic infection extremely limited
Chemical Name: Bifidobacterium brevis (live or freeze-dried bacterial culture)
Percent Content: Typically 95–99%, depending on formulation
Other Components: May include trace residual growth media, stabilizers (e.g., maltodextrin), cryoprotectants (e.g., skim milk powder) in low percentages
Purity: Specified by batch; quality control data supplied on request
Common Allergens: Dairy proteins possible if used as stabilizer; users with allergies should consult detailed product documentation
Genetic Modification Status: Non-GMO strains used in food and supplement applications according to regulatory standards
Inhalation: Remove to fresh air; if irritation persists, seek medical attention
Skin Contact: Wash skin with soap and water; if irritation develops or persists, consult a healthcare professional
Eye Contact: Rinse eyes cautiously with water for at least 15 minutes; consult medical advice if discomfort continues
Ingestion: Rinse mouth with water; individuals with immune compromise or allergies should watch for symptoms and obtain medical guidance
Medical Attention: Healthcare providers should be alerted to underlying conditions that may heighten risk (e.g., immunocompromised states)
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide extinguishing agents
Unsuitable Extinguishing Media: None known; product does not support combustion
Special Hazards from Fire: Product classified as non-flammable; in the event of fire involving packaging, toxic fumes from plastic or paper may occur
Protective Equipment for Firefighters: Standard protective clothing and NIOSH-approved self-contained breathing apparatus for smoke exposure
Other Information: Move containers from fire area if it can be done safely; avoid breathing combustion products
Personal Precautions: Use gloves, protective eyewear, and dust mask or respirator if high concentration release produces dust
Environmental Precautions: Prevent uncontrolled release into water systems; avoid generating airborne dust
Clean-Up Methods: Sweep or vacuum spillage into sealed, labeled containers for disposal or recycling; wash area with water and detergent
Disposal: Collect all material in accordance with local, regional, and national regulations; avoid washing into drains
Other Instructions: Ventilate the area during clean-up; ensure surfaces are thoroughly cleaned to prevent growth or contamination
Handling: Minimize dust generation and prevent inhalation; wash hands and equipment after use; maintain cleanliness to avoid microbial contamination in workplace
Storage Conditions: Store sealed in original containers at recommended temperatures (usually refrigerated or frozen for longest shelf life); keep away from moisture, direct sunlight, or extreme heat
Incompatible Materials: Avoid strong acids, bases, and oxidizers; do not store near compounds that may cause degradation
Packaging Materials: Use food-grade, airtight, inert packaging to preserve viability; broken packages must be resealed promptly
Special Instructions: Product stability and potency decrease with exposure to air, light, heat, and moisture
Engineering Controls: Use local exhaust ventilation if dust or aerosols are generated or in large-scale processing areas
Personal Protective Equipment (PPE): Protective gloves, lab coat or coveralls, safety goggles, and suitable particulate respirator (N95 or better) during handling
Hygiene Measures: Wash hands after handling and before eating or drinking; launder contaminated clothing regularly
Exposure Limits: No specific occupational exposure limits set; general microbiological safety guidelines apply
Special Protection: Individuals with allergies, ongoing chronic respiratory or immune issues should take extra precautions
Appearance: Off-white to light beige powder; color may vary slightly depending on formulation
Odor: Slight, dairy-related natural scent; may vary depending on carrier and stabilizer
pH (1% solution): Typically 5.0 to 7.0
Solubility: Dispersible in water, insoluble in most organic solvents
Boiling Point/Melting Point: Not applicable for microbial powder
Bulk Density: 0.3–0.6 g/cm³
Flash Point: Not combustible
Auto-Ignition Temperature: Not relevant for biological material
Other Properties: Not explosive; no oxidizing properties; particle size varies by manufacturer
Chemical Stability: Stable for 1–2 years at recommended low temperatures in sealed packaging; rapid loss of viability occurs with heat, moisture, or air exposure
Reactivity: Not reactive with common laboratory reagents under standard conditions; decomposes under acidic or oxidative extremes
Conditions to Avoid: Heat above 25°C, high humidity, sunlight, exposure to open air
Incompatible Materials: Strong acids, bases, oxidizing agents; avoid storage near incompatible chemicals to prevent accidental degradation
Hazardous Decomposition Products: None expected under normal use or storage
Polymerization: Not applicable
Acute Toxicity: No known acute toxicity in healthy adults; ingestion regarded as low risk for general public at customary doses; rare allergic reaction or gastrointestinal upset possible in sensitive individuals
Chronic Toxicity: Long-term effects not anticipated with normal use
Skin/Eye Irritation: Unlikely except in rare cases of hypersensitivity; may cause mild irritation if product contacts mucous membranes in high amounts
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA
Mutagenicity/Teratogenicity: No mutagenic, teratogenic, or reproductive toxicity observed in available studies
Target Organ Effects: None identified in healthy humans
Special Risk Groups: Individuals with known allergies to components, underlying immunodeficiency, or at-risk digestive health should consult their healthcare provider
Ecotoxicity: No bioaccumulation or persistence expected in environment; product consists of non-pathogenic, naturally occurring gut bacteria species; should not disrupt native flora when released in small, controlled amounts
Mobility: Limited; organisms unlikely to survive long outside controlled environments due to lack of suitable nutrients and temperatures
Degradability: Decomposes naturally; quickly broken down by native soil or aquatic microbial communities
Aquatic Toxicity: No evidence of toxicity to aquatic plants or animals at environmentally relevant concentrations
Other Details: Mass proliferation outside the host is unlikely due to ecological competition
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations for non-hazardous biological materials
Sewage Disposal: Avoid introducing concentrated cultures directly to sewage systems; treat as general organic waste
Packaging Disposal: Empty containers can be recycled or landfilled after thorough cleaning; deface all labels if reused
Precautions: Take care to prevent accidental aerosolization or dust formation during disposal; do not incinerate without regulatory approval
UN Number: Not regulated for transport
Proper Shipping Name: Non-hazardous, non-pathogenic microbial culture; description may vary by jurisdiction
Transport Hazard Class: Not assigned
Packing Group: Not determined
Special Precautions: Maintain cold chain for products requiring refrigeration; ship in sealed, leak-proof containers to preserve viability and contain any spillage
Regulatory Notes: Generally allowed for air, land, and sea shipment as non-restricted cargo; consult carrier for specific packaging and documentation formats
Environmental Hazards: None expected during normal transport
US Regulations: Bifidobacterium brevis commonly listed as Generally Recognized as Safe (GRAS) for food applications by the US FDA; falls under the scope of the Food, Drug, and Cosmetic Act depending on destination use
EU Regulations: Listed on the Qualified Presumption of Safety (QPS) list for food and feed; subject to labeling under EU food and feed safety regulations
Other Regulatory Bodies: Compliance with standards set by Codex Alimentarius, Health Canada, China Food and Drug Administration, Japanese Ministry of Health, and other local authorities
Worker Protection: OSHA general duty clause applies; good laboratory/hygiene practices required
Product Labeling: Allergen statements and viability counts included per jurisdiction
Additional Requirements: Manufacturer provides supporting documentation, certificates of analysis, and compliance declarations upon request
