Product Name: Betaine
Chemical Name: Trimethylglycine
CAS Number: 107-43-7
Recommended Uses: Laboratory chemicals, cosmetic additives, feed additives, personal care product ingredient
Manufacturer Information: Supplier’s full contact details including address, emergency phone number, and email contact.
SDS Number: Noted on supplied MSDS document
Synonyms: Glycine, N,N,N-trimethyl-
Relevant Identified Uses and Restrictions: Industrial use, professional use, not for direct ingestion by animals or humans except as specified in regulated products
GHS Classification: Not classified as hazardous under GHS criteria
Label Elements: No pictogram or signal word required; precautionary statements related to general hygiene
Hazard Statements: May cause mild eye or skin irritation in sensitive individuals
Precautionary Statements: Avoid contact with eyes and prolonged skin exposure. As a dust, may cause mild respiratory tract irritation
Other Hazards: Combustible dust hazard if finely divided and dispersed in air
Physical Hazards: No special physical hazard—combustible but not explosive
Chemical Composition: Betaine (Trimethylglycine) 98–100%
Impurities: Trace water; possible trace amounts of related amino acid derivatives
EC Number: 203-490-6
Molecular Formula: C5H11NO2
Molecular Weight: 117.15 g/mol
Substance or Mixture: Substance
Inhalation: Move the person to fresh air. Seek medical attention if symptoms persist or cough occurs.
Skin Contact: Wash affected area thoroughly with soap and water. Remove contaminated clothing. Get medical attention for persistent irritation.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing for at least 15 minutes.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Seek medical attention for large amounts ingested or if symptoms occur.
Important Symptoms or Effects: Mild irritation possible to skin, eyes, and upper respiratory tract; rare allergic reaction reported in sensitive persons
Advice to Physicians: Provide symptomatic treatment. Monitor for allergic reaction or respiratory difficulty.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Specific Hazards Arising from the Chemical: Emits nitrogen oxides, carbon oxides under fire conditions. Fine dust in air forms explosion hazard
Special Protective Equipment for Firefighters: Full protective clothing and self-contained breathing apparatus
Fire and Explosion Hazards: Combustible dust cloud may explode if dispersed in air and ignited
Advice for Firefighters: Evacuate area. Avoid inhaling fumes. Apply standard firefighting techniques
Personal Precautions: Avoid dust formation. Use protective gear including gloves and safety goggles.
Environmental Precautions: Prevent from entering drains or watercourses. Contains no ingredients posing acute threat to aquatic life.
Methods for Cleaning Up: Collect material with sweeping or vacuuming. Place in suitable, sealed containers for disposal. Use non-sparking tools.
Reference to Other Sections: For personal protection see Section on Exposure Controls and Personal Protection.
Precautions for Safe Handling: Avoid generation of dust. Practice good industrial hygiene—wash thoroughly after handling. Do not eat, drink, or smoke while using the product.
Conditions for Safe Storage: Store in original tightly closed container, in a cool, dry, well-ventilated area. Protect from moisture. Keep away from ignition sources.
Incompatible Materials: Strong oxidizing agents
Specific End Uses: See product label and use in accordance with local guidelines
Control Parameters: No occupational exposure limits established by OSHA, ACGIH, or similar agencies
Engineering Controls: Adequate local exhaust ventilation for dust control. Use dust collection systems when transferring or mixing.
Personal Protective Equipment: Protective gloves, eye protection (goggles or safety glasses), dust mask (P2 or N95 grade) in high dust conditions
Hygiene Measures: Wash hands before breaks and after use. Remove contaminated clothing and wash before reuse.
Appearance: White crystalline powder
Odor: Odorless
Melting Point: 293–295°C
Boiling Point: Not applicable—decomposes before boiling
Flash Point: Not flammable in the standard sense
Evaporation Rate: Not applicable
Flammability (Solid, Gas): Not classified as flammable
Vapor Pressure: Negligible at 20°C
Solubility: Completely soluble in water
Partition Coefficient (n-octanol/water): Log Kow -4.15 (high water solubility)
Auto-Ignition Temperature: No data
Decomposition Temperature: >293°C
Viscosity: Not applicable
Density: Approximately 1.26–1.28 g/cm3
Reactivity: Stable under recommended handling and storage conditions
Chemical Stability: Stable at room temperature under normal conditions
Possibility of Hazardous Reactions: None known under normal use and storage
Conditions to Avoid: Excess heat, open flame, high humidity, generation of dust clouds
Incompatible Materials: Strong oxidizers
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide and dioxide released during combustion or decomposition
Acute Toxicity: Oral LD50 (rat) > 10,000 mg/kg (very low acute toxicity)
Skin Corrosion/Irritation: Not classified as hazardous. Mild irritation possible in sensitive individuals
Serious Eye Damage/Irritation: Mild irritation possible
Respiratory Sensitization: No evidence in human or animal studies
Skin Sensitization: No evidence; reports of rare reactions
Germ Cell Mutagenicity: No mutagenic potential in standard test systems
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA
Reproductive Toxicity: No known reproductive toxicity
Specific Target Organ Toxicity: No specific findings
Aspiration Hazard: Not applicable given physical format
Ecotoxicity: Not expected to be hazardous to aquatic life based on available data
Persistence and Degradability: Readily biodegradable according to OECD criteria
Bioaccumulative Potential: Low bioaccumulation potential based on high water solubility and log Kow
Mobility in Soil: High mobility due to complete water solubility; possible leaching to groundwater in excessive releases
Other Adverse Effects: None known
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations
Product Disposal: Handle as non-hazardous waste; landfill or incinerate as appropriate to local requirements
Contaminated Packaging: Clean containers for recycling or disposal; ensure container is empty before recycling
Legal Restrictions: Product and packaging disposal subject to regional environmental agency rules
UN Number: Not regulated for transport
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not hazardous for environment under transport regulations
Special Shipping Precautions: Keep dry and protect from moisture during transport
Safety, Health, and Environmental Regulations Specific for the Substance: Subject to workplace regulations relating to chemical substances
US Regulations: The substance appears on the TSCA inventory. Not listed under SARA Title III or CERCLA
EU Regulations: Registered under REACH; no restrictions applicable
Other Regulations: Not considered hazardous under Workplace Hazardous Materials Information System (WHMIS) in Canada
Chemical Safety Assessment: Chemical safety assessment conducted as per regulatory standards