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Product Name: Aspergillus Terreus Culture
Synonyms: Not applicable
Recommended Use: Laboratory research, industrial biotechnology, enzyme production
Manufacturer Information: Name, address, and emergency contact phone specific to your provider
Product Code: Internal reference number, batch code
Classification: Fungal culture, potential biohazard; not classified as hazardous under GHS for chemical risks but recognized as risk group 2 pathogen
Hazard Statements: Allergenic in sensitive individuals, may cause respiratory irritation, can cause opportunistic infections, not known to cause acute toxicity through single exposure
GHS Label Elements: No specific chemical hazard pictogram; biological risk pictogram recommended in laboratory settings
Routes of Exposure: Inhalation of spores, skin contact, ingestion unlikely due to handling procedures
Aggravating Conditions: Immunocompromised individuals, pre-existing lung disease
Component: Aspergillus Terreus spores and vegetative cells
Concentration: Live culture may vary, often supplied in suspension, lyophilized powder, or on solid agar
Supporting Ingredients: Agar, peptone, water, glucose or minimal nutrient salts depending on culture medium
Chemical Additives: Sometimes storage buffers (PBS, glycerol), no hazardous chemicals commonly used
Inhalation: Move individual to fresh air, monitor for signs of respiratory distress, seek medical advice for breathing difficulty, especially in immunosuppressed or asthmatic individuals
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, seek doctor’s attention if rash, irritation, or infection develops
Eye Contact: Rinse immediately with clean water for at least fifteen minutes, consult a healthcare professional if irritation, redness, or pain persists
Ingestion: Unlikely route, but rinse mouth with water, seek medical attention if discomfort occurs or symptoms develop
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide for fire in immediate area
Specific Hazards Arising From Product: Dried spores and cell masses may combust; burning produces simple organic residues and smoke
Protective Equipment: Wear self-contained breathing apparatus and chemical splash suit; avoid inhalation of fire-generated dust and smoke
Special Precautions: Minimize disturbance of material to prevent airborne spores
Personal Precautions: Put on gloves, gown, and mask or respirator; ventilate area if possible to avoid spore build-up
Environmental Precautions: Prevent large spills from entering drains, water courses, or open soil as spores could proliferate
Method for Clean-up: Gently cover spilled material with absorbent cloth dampened with disinfectant, use HEPA-filtered vacuum if needed, dispose of clean-up materials in biohazard bag, disinfect surfaces
Handling: Work in certified biosafety cabinets for open culture, wear lab coat, gloves, and respiratory protection if splashes or aerosols can occur, avoid creating dust or aerosols
Storage: Store in sealed containers at recommended temperature (commonly 2-8°C for working cultures, -80°C for long-term storage), clear biohazard labeling required, restrict access to authorized staff
Engineering Controls: Biosafety Level 2 laboratory facilities suited for non-airborne pathogens with careful procedure design to minimize aerosol generation
Personal Protective Equipment (PPE): Impervious gloves, lab coat, safety goggles or face shield, fit-tested respirator for dusty operations, hand washing after handling
Hygiene Measures: Do not eat, drink, or smoke within laboratory, clean work surfaces routinely, autoclave contaminated materials
Exposure Limits: No established occupational exposure limits; prudent practices required
Appearance: Tan to light brown fuzzy mold, fine granular or powdery when dried, creamy or chalky on standard agar or broth
Odor: Earthy or musty odor typical of filamentous fungi
pH: Neutral to slightly acidic in solution
Melting/Freezing Point: Not applicable for biological material
Flash Point: Not flammable in biological suspension form
Solubility: Insoluble in water as intact mycelia or spores; dispersible in aqueous buffers
Vapor Pressure: Nearly none
Density: Variable based on culture form (liquid or dried mass), typically low bulk density
Chemical Stability: Stable under recommended storage conditions, spores persist for months if kept dry and cool
Reactivity: Not reactive with common laboratory chemicals
Conditions to Avoid: Extreme heat, direct sunlight, excess moisture, uncontrolled open air
Incompatible Materials: Strong oxidizers may degrade cells, disinfectants inactivate spores
Decomposition Products: Decomposes to simple organics if burned or exposed to strong oxidants
Possible Acute Effects: Respiratory irritation, cough, allergic reactions, asthma-like symptoms, rare cases of invasive aspergillosis, especially in compromised hosts
Sensitization: Long-term handling can cause sensitization and allergic reactions
Carcinogenicity: Not listed as carcinogenic, but chronic irritation possible through prolonged exposure
Mutagenicity: No evidence found in available literature for standard lab strains
Other Effects: May produce mycotoxins under some conditions, including terreic acid, but these are not typical at low exposure levels in the lab
Ecotoxicity: Naturally occurring soil fungus, can antagonize plant pathogens, but large-scale releases could disrupt local microflora or cause unwanted growth
Persistence and Degradability: Spores persist in soil and dust, resistant to desiccation, sensitive to high temperature and extreme pH
Bioaccumulative Potential: Not expected to bioaccumulate in animals
Mobility in Soil: Spores spread readily through air and water, colonize a wide range of substrates
Other Adverse Effects: May contribute to spoilage of stored agricultural products if accidental dissemination occurs
Waste Treatment Methods: Autoclave all solid or liquid waste, use EPA-registered broad-spectrum disinfectant for surface decontamination, segregate contaminated disposables as biohazard waste
Contaminated Packaging: Decontaminate or autoclave containers prior to disposal, follow institutional and local biohazard waste protocols
Disposal of Unused Product: Incinerate or chemically disinfect according to laboratory safety committee or local regulation
UN Number: UN 3373 Biological Substance, Category B for diagnostic specimens or cultures
Proper Shipping Name: Biological Substance, Culture - Aspergillus terreus
Transport Hazard Class: Category B Infectious Substances for UN3373; otherwise not a hazardous chemical
Packing Group: Not assigned
Special Precautions: Double-containment packaging, absorbent liner, clear labeling required as per IATA/ADR, transport only by licensed carriers capable of handling biological material
OSHA: Covered under OSHA Laboratory Standard, must implement exposure control plans
EPA: No direct regulation as a chemical, disposal governed by local environmental health services
DOT: Shipping as infectious substance or exempt if inactivated; must comply with all federal transport requirements
IATA: Air shipment as UN 3373 Category B or equivalent local requirement
Other Requirements: Material subject to institutional biosafety approval for use and disposal, may require recordkeeping and incident reporting, state or country specific regulations may apply
