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Product Name: Aspartame
Chemical Formula: C14H18N2O5
CAS Number: 22839-47-0
Synonyms: L-alpha-Aspartyl-L-phenylalanine methyl ester
Recommended Use: Artificial sweetener for food and beverage industries
Supplier: Food additives or chemical manufacturer information varies by source
Contact Information: Emergency contact varies by region; refer to local guidelines or manufacturer support
Hazard Classification: Not classified as dangerous according to GHS; some users report allergic-type sensitivities
Label Elements: Not subject to detailed hazard labeling under OSHA or GHS
Routes of Exposure: Ingestion, inhalation, eye and skin contact
Symptoms: May cause mild irritation to eyes, skin, or gastrointestinal tract in rare cases
Other Hazards: Heating above 150°C releases methanol, a toxic substance; dust inhalation can irritate the respiratory system
Chemical Name: Aspartame
Pure Substance: Yes
CAS Number: 22839-47-0
Concentration: 100% as supplied
Impurities: May contain traces of related substances (L-Aspartyl, L-Phenylalanine, diketopiperazine) depending on manufacturing process
Inhalation: Move to fresh air; seek medical attention if symptoms persist
Eye Contact: Rinse immediately with water for at least 15 minutes; remove contact lenses if present; seek medical attention if irritation continues
Skin Contact: Wash with soap and plenty of water; remove contaminated clothing
Ingestion: Rinse mouth with water; drink water to dilute; call poison control or seek medical advice if large quantities consumed; monitor for headaches, dizziness, or gastrointestinal discomfort
Suitable Extinguishing Media: Water spray, dry chemical powder, foam, carbon dioxide
Special Hazards: Decomposition during fire can release carbon monoxide, carbon dioxide, nitrogen oxides, and methanol
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing recommended
Explosion Risk: Dust-air mixtures might become a minor explosion hazard under certain conditions of confinement and ignition
Personal Precautions: Avoid inhalation or skin contact, ensure adequate ventilation, use dust masks and gloves
Environmental Precautions: Prevent large spills from entering waterways; sweep up and transfer to labeled containers for disposal
Cleanup Methods: Use broom or vacuum equipped with HEPA filter; avoid creating airborne dust; wash area with water to clear residues; dispose as per local regulations
Safe Handling: Use in well-ventilated areas, minimize dust generation, avoid contact with skin or eyes, do not ingest
Storage: Store in a tightly closed container in a cool, dry, well-ventilated place
Incompatibilities: Keep away from strong acids, bases, and oxidizing materials; avoid extended exposure to heat and moisture
Specific Requirements: Keep away from food and animal feeds not intended for human consumption to avoid accidental exposure
Engineering Controls: Local exhaust ventilation recommended in areas with dust generation
Respiratory Protection: Dust mask or respirator (NIOSH approved) if airborne dust exceeds regulatory limits
Skin Protection: Wear disposable or chemical-resistant gloves
Eye Protection: Safety goggles if risk of dust contact
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing, do not eat or drink while handling
Exposure Limits: No specific OSHA or ACGIH limits set; maintain airborne levels as low as reasonably achievable
Appearance: White, crystalline powder
Odor: Odorless
Solubility: Slightly soluble in water; more soluble in alcohol
Melting Point: 246–247°C (with decomposition, releases methanol)
Boiling Point: Decomposes before boiling
Density: Approx. 1.35 g/cm³
pH: 4.5–6.0 (1% solution)
Vapor Pressure: Not applicable
Partition Coefficient: Log Pow estimated near -1.6; does not bioaccumulate
Other Physical Data: Stable under normal conditions; no explosive or oxidizing properties
Chemical Stability: Stable under recommended storage conditions
Reactive Under Conditions: Exposure to acids or bases, heat, or light may cause decomposition
Decomposition Products: Methanol, diketopiperazine, carbon dioxide, nitrogen oxides on thermal decomposition
Other Reactivity: Not reactive with most inert materials; avoid strong oxidizers
Acute Toxicity: Oral LD50 (rat): >5,000 mg/kg (low toxicity)
Inhalation: Dust irritation possible
Skin Irritation: Not a common irritant, but may cause minor reactions in sensitive individuals
Eye Irritation: May cause mild redness or irritation on contact
Chronic Effects: Aspartame breaks down into phenylalanine, aspartic acid, and methanol; high intake is dangerous for those with phenylketonuria (PKU)
Carcinogenicity: Major regulatory agencies (FDA, EFSA, WHO) do not recognize aspartame as a carcinogen based on current science
Reproductive Toxicity: No evidence of harm at approved consumption levels
Sensitization: Rare allergic-type reactions reported, but no clear link to immune sensitivity
Other Health Issues: Possible headaches, allergic reactions, or mood swings documented anecdotally
Aquatic Toxicity: Limited data, expected to have low acute toxicity to aquatic organisms
Soil Mobility: Low; substance remains near surface without extensive leaching due to moderate solubility
Persistence and Degradability: Readily biodegradable in soil and water by microbes
Bioaccumulation Potential: Does not bioaccumulate in living tissue
Other ECO Information: No evidence of environmental harm at standard use and disposal levels; monitor large releases to waterways for local effects
Waste Treatment: Dispose as non-hazardous organic waste in accordance with local, regional, and national controls
Incineration: High temperatures break down aspartame to simple gases; ensure flue gas cleaning
Packaging: Triple rinse containers before recycling or disposal; label as containing food additive material
Environmental Precautions: Avoid releasing large quantities into water systems, stick to sewer regulations
UN Number: Not regulated as a hazardous material
Proper Shipping Name: Not restricted
Transport Hazard Class: None assigned
Packing Group: Not applicable
Marine Pollutant: Not considered a marine pollutant
Special Precautions for Transport: Avoid moisture during shipment; store containers to prevent damage or leaks
Labeling Requirements: Not classified as hazardous under US OSHA, EU CLP, or UN guidelines; food labeling required for products containing aspartame
International Inventories: Listed on TSCA, EINECS, DSL
Food Standards: Approved worldwide with safe intake limits set by WHO (40 mg/kg body weight/day) and FDA (50 mg/kg body weight/day)
Other Regulatory Details: Specific warnings for phenylketonurics mandatory in many countries; follow local food additive regulations
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
