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MSDS for Analgin

Identification

Product Name: Analgin
SYNONYMS: Metamizole Sodium, Dipyrone, Novalgin
Chemical Formula: C13H16N3NaO4S
CAS Number: 68-89-3
Intended Use: Analgesic, Antipyretic
Manufacturer: Detailed information requested from individual supplier
Contact Phone: Emergency numbers found on shipping label or regional poison centers

Hazard Identification

Classification: Acute Toxicity (Oral), Eye Irritation, Specific Target Organ Toxicity
GHS Label: Skull and crossbones pictogram for acute toxicity, exclamation mark for irritation
Hazard Statements: Harmful if swallowed, causes eye and respiratory irritation, may cause allergic reactions such as agranulocytosis
Precautionary Statements: Avoid breathing dust. Wear protective gloves and eye protection. Wash hands thoroughly after handling

Composition / Information on Ingredients

Chemical Name: Metamizole Sodium
CAS Number: 68-89-3
Content: >98% pure
Impurities: Trace solvents and byproducts, content depends on manufacturing process

First Aid Measures

Inhalation: Move to fresh air. Seek medical attention if symptoms such as shortness of breath or coughing develop.
Skin Contact: Remove contaminated clothing. Rinse skin immediately with plenty of water. Seek medical advice if irritation persists.
Eye Contact: Rinse eye thoroughly with plenty of water for at least 15 minutes, holding eyelids open. Look for medical attention if discomfort continues.
Ingestion: Rinse mouth. Do not induce vomiting without medical advice. Seek immediate medical care.

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, CO2, dry chemical, or foam.
Fire Hazards: Product may release toxic fumes of sulfur oxides, nitrogen oxides, and carbon monoxide when burned.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and complete protective gear.
Other Information: Move containers away from the fire area if possible. Cool sealed containers with water spray to prevent explosion.

Accidental Release Measures

Personal Precautions: Use appropriate personal protection equipment (gloves, goggles, respiratory mask). Avoid dust formation.
Environmental Precautions: Prevent entry into drains, sewers, or watercourses.
Methods for Clean Up: Sweep up and shovel into containers for disposal. Wash spill site after material pickup is complete.

Handling and Storage

Safe Handling: Handle in well-ventilated areas. Prevent dust accumulation. Avoid contact with skin, eyes, and clothing.
Storage Conditions: Store in tightly closed containers in a cool, dry, and well-ventilated location. Keep away from strong oxidizers and moisture.
Incompatible Materials: Acids, oxidizing agents, and combustible materials.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established occupational exposure limits for Analgin in most jurisdictions.
Engineering Controls: Work under adequate ventilation or fume hoods. Use dust extraction if high amounts of dust could be generated.
Personal Protective Equipment: Protective gloves (nitrile recommended), chemical safety goggles, lab coats, and respiratory protection for large spills or powder handling.

Physical and Chemical Properties

Appearance: White to slightly yellow, crystalline powder
Odor: Odorless
Melting Point: About 163-170 °C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Readily soluble in water
Molecular Weight: 333.36 g/mol
Flash Point: Not available
pH (aqueous solution): 6-7.5
Vapor Pressure: Negligible

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: May react with strong oxidizing agents or acids
Hazardous Decomposition Products: Emits sulfur oxides, nitrogen oxides, and carbon monoxide during thermal decomposition
Conditions to Avoid: Air, moisture, extreme heat, and sunlight

Toxicological Information

Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: May cause irritation of eyes, skin, and respiratory tract. Can result in allergic reactions, particularly agranulocytosis.
Chronic Effects: Prolonged exposure may lead to blood disorders, especially low white cell counts.
LD50 (Oral, Rat): Estimated around 1800 mg/kg
Carcinogenicity: Not classified as carcinogenic by IARC or NTP

Ecological Information

Aquatic Toxicity: Data limited, but considered not acutely toxic to aquatic organisms in low concentrations.
Mobility in Soil: High water solubility suggests potential to leach into groundwater.
Persistence and Degradability: Moderately biodegradable in soil and water.
Bioaccumulation: Not expected to bioaccumulate due to low log Kow.

Disposal Considerations

General Waste Disposal: Dispose of in accordance with local, regional, and national regulations.
Contaminated Packaging: Triple rinse containers and offer for recycling or proper landfill.
Special Considerations: Do not discharge unused material into natural waterways.

Transport Information

UN Number: Not assigned for Analgin bulk chemical
Transport Hazard Class: Not classified as a hazardous material for ground, sea, or air transport.
Packing Group: Not regulated
Environmental Hazards: Not considered marine pollutant

Regulatory Information

Regulatory Status: Check relevant country or state guidelines; banned or restricted in some regions.
OSHA Status: Not specifically listed
SARA Section 313: Not subject
TSCA: Listed in the US Toxic Substances Control Act Inventory
REACH Registration: Required for manufacture or import in the European Union
Other Regulations: Local and regional restrictions may apply; consult health authorities and customs offices for detailed legal status