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Product Name: Ammonium Glycyrrhizinate
Chemical Formula: C42H65NO16
Chemical Family: Glycyrrhizic acid salt
CAS No.: 53956-04-0
Synonyms: Glycyrrhizate ammonium salt
Recommended Use: Food additive, pharmaceutical ingredient, cosmetic agent
Supplier: [Insert Supplier Information if required by regulation]
Emergency Contact: [Insert Emergency Number if required by regulation]
GHS Classification: Not classified as hazardous under GHS criteria
Hazard Statements: May cause mild irritation to eyes, skin, and respiratory tract
Pictogram: Not applicable
Signal Word: None
Precautionary Statements: Avoid contact with eyes and prolonged skin contact; avoid generating dust; wash hands after handling
Potential Health Effects: Mild irritation to skin and eyes; prolonged inhalation or contact may cause sensitivity in some individuals
Environmental Effects: No significant environmental hazards when used and disposed of as directed
Chemical Name: Ammonium Glycyrrhizinate
CAS No.: 53956-04-0
Percent: >95%
Impurities: Glycyrrhizinic acid derivatives (<5%), water
Additives: None known
Eye Contact: Rinse gently with plenty of water, lifting eyelids occasionally; seek medical attention if irritation persists
Skin Contact: Wash with soap and water; remove contaminated clothing; get medical help if redness or irritation appears
Inhalation: Move to fresh air; keep at rest; get medical advice if symptoms develop
Ingestion: Rinse mouth; drink water to dilute; do not induce vomiting; get medical attention if feeling unwell
Most Important Symptoms: Slight eye or skin irritation, possible mild allergic reaction in sensitive individuals
Suitable Extinguishing Media: Water spray, carbon dioxide, foam, dry chemical
Unsuitable Extinguishing Media: None known
Specific Hazards: Product can burn in fire, releasing carbon oxides and nitrogen oxides
Protective Equipment: Firefighters use self-contained breathing apparatus and protective clothing
Special Procedures: Cool containers with water spray to prevent rupture; avoid inhaling combustion gases
Personal Precautions: Use protective gloves, goggles, and a dust mask; avoid creating airborne dust
Environmental Precautions: Prevent spillage into drains, water courses, and soil
Methods for Clean-up: Sweep up spilled material without generating dust; collect in suitable, sealed containers for proper disposal; wash area with water after collection
Handling: Use with adequate ventilation; avoid inhaling dust or contact with skin and eyes; wash hands after handling
Storage Conditions: Store in dry, cool, well-ventilated area; keep container tightly closed and away from incompatible substances such as strong oxidizers
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Special Precautions: Protect from moisture and direct sunlight; keep separate from food or animal feed
Occupational Exposure Limits: No established limits; maintain general dust exposure below nuisance dust threshold (<10 mg/m3 for total dust)
Engineering Controls: Local exhaust ventilation, dust extraction, or similar engineering controls
Eye Protection: Safety goggles
Skin Protection: Protective gloves, laboratory coat
Respiratory Protection: Dust mask or respirator if dust generated in process
Hygiene Measures: Wash thoroughly after handling, before eating or drinking
Appearance: White to off-white powder
Odor: Characteristic, faintly sweet
Odor Threshold: Not determined
pH: 5.0–7.0 (1% solution in water)
Melting Point: Decomposes above 200°C
Boiling Point: Not applicable
Flash Point: Not flammable
Evaporation Rate: Not determined
Flammability: Not highly flammable under normal conditions
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Relative Density: 1.3–1.5 g/cm3
Solubility: Soluble in water
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 200°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: No hazardous reactions under normal use
Incompatible Materials: Strong oxidants, concentrated acids or bases
Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and possibly ammonia
Hazardous Polymerization: Does not occur
Acute Toxicity: Oral LD50 (rat) >2000 mg/kg (low toxicity)
Skin Corrosion/Irritation: May cause mild irritation with prolonged contact
Serious Eye Damage/Irritation: May produce mild, reversible eye irritation
Respiratory or Skin Sensitization: Sensitization possible in sensitive individuals upon repeated contact
Carcinogenicity: No data to suggest carcinogenic risk
Mutagenicity: Not considered mutagenic
Reproductive Toxicity: No documented adverse effects on reproduction
Other Effects: Large oral doses may cause hypertension or fluid retention due to glycyrrhizin properties; monitoring recommended
Aquatic Toxicity: Not expected to be harmful to aquatic life at typical environmental concentrations
Persistence and Degradability: Biodegradable
Bioaccumulation Potential: Low potential for bioaccumulation
Mobility in Soil: Product is water-soluble and may migrate in soil
Other Adverse Effects: No data on disruption to ecosystem at standard usage concentrations
General Disposal: Dispose as non-hazardous organic waste in accordance with local regulations
Container Disposal: Triple rinse containers, then recycle or dispose as approved by authorities
Precautions: Prevent material from entering natural water sources or sewers in large quantities
UN Number: Not regulated
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not assigned
Marine Pollutant: No
Special Precautions: Protect from moisture during transport; keep containers closed and secure
US TSCA: Listed
EU REACH: Exempt or not yet registered, due to usage profile
FDA: Approved for use in food and cosmetic applications according to specific guidelines
Labeling Requirements: According to local laws, label as “Not hazardous” but include advisory for dust and mild irritancy
Other Regulations: Observe workplace and environmental controls as indicated; check for additional regional or national laws relevant to pharmaceutical or cosmetic applications
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
