© 2026 Alchemist Worldwide Ltd,
All Right Reserved
Product Name: Acetohydroxamic Acid
Chemical Formula: C2H5NO2
CAS Number: 546-88-3
Synonyms: N-Hydroxyacetamide, AHA
Intended Use: Pharmaceutical intermediate, chemical research
Manufacturer/Distributor: Comprehensive identification helps responders and handlers know exactly what’s present, reducing confusion in high-stakes moments.
Address and Contact Information: Manufacturers typically include accurate emergency lines, ensuring users can source help when accidents happen.
GHS Classification: Acute toxicity (oral, dermal, inhalation), target organ effects
Hazard Symbols: Skull and crossbones, exclamation mark
Signal Word: Danger
Hazard Statements: Causes serious eye and skin irritation; may be harmful if swallowed, inhaled, or absorbed through skin; risk of organ damage after repeated exposure.
Precautionary Statements: Wear protective equipment, work in well-ventilated areas, avoid breathing dust and direct contact, wash hands after use.
Other Hazards: Not flammable, but decomposition releases toxic fumes under fire; severe exposure risks justify clear warnings.
Chemical Name: Acetohydroxamic Acid
CAS Number: 546-88-3
Concentration: >98% pure in standard lab-grade containers
Impurities: Trace moisture, residual solvents can occasionally increase risk.
Properties: White to off-white crystalline powder, forms a solution in water.
Eye Contact: Rinse cautiously with water for 15 minutes, seek medical help immediately. Immediate rinsing can limit damage and long-term complications.
Skin Contact: Remove contaminated clothing; rinse skin thoroughly with soap and water.
Inhalation: Move person to fresh air, provide artificial respiration if breathing stops, get medical attention.
Ingestion: Do not induce vomiting; rinse mouth, drink water if conscious, seek medical help without delay.
Symptoms: Itching, burning, headache, shortness of breath signal overexposure. Medical staff need symptom descriptions to give targeted care.
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide for surrounding fires.
Special Hazards: Thermal decomposition can emit nitrogen oxides and carbon monoxide, which should trigger added caution for responders.
Protective Equipment: Firefighters should use full protective gear and self-contained breathing apparatus, especially in poorly ventilated environments.
Advice for Firefighters: Prevent runoff, keep containers cool with water if safe, stay upwind to avoid toxic fumes.
Personal Precautions: Limit access to affected area, put on gloves, chemical goggles, lab coats, and suitable respiratory gear.
Environmental Precautions: Prevent further leakage or spillage if safe, avoid contact with soil and waterways.
Clean-Up Methods: Gather spilled material with inert absorbent, sweep into chemical waste container, ventilate area, wash spill site with water after initial clean-up.
Disposal: Place collected material in properly labeled waste containers for disposal according to local regulations.
Handling: Use in fume hoods or well-ventilated spaces, avoid dust formation, keep containers sealed when not in use. Training workers and ensuring proper procedure follow-through reduce mistakes.
Storage: Store in a dry, cool, tightly closed container, keep away from direct sunlight, heat, and incompatible chemicals like strong oxidizers and acids.
Storage Class: Chemical storage guidelines suggest placing acetohydroxamic acid in designated corrosive chemical cabinets.
Exposure Limits: No established occupational exposure limits, but extra vigilance matters in research settings.
Engineering Controls: Use fume hoods, local exhaust, adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment: Gloves (nitrile, neoprene), chemical goggles, lab coat, sometimes respirators for dust.
Hygiene Measures: Wash hands and exposed skin after handling, avoid eating, drinking, or smoking in work areas.
Appearance: White crystalline powder
Odor: Faint, slightly acidic
pH: Slightly acidic in water
Melting Point: 86-89°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol; limited solubility in organic solvents.
Vapor Pressure: Negligible at room temperature
Flash Point: Not data available due to decomposition
Density: 1.37 g/cm³
Stability: Stable under specified with recommended storage conditions.
Chemical Stability: Stable in cool, dry, ventilated spaces. Decomposes with heat, moisture, strong acids, oxidizing agents.
Conditions to Avoid: High humidity, elevated temperatures, incompatible substances.
Hazardous Reactions: Contact with oxidizers increases fire and toxic release risk.
Decomposition Products: Nitrogen oxides, carbon monoxide, acetic acid fumes. Proper handling reduces accidental exposure.
Acute Toxicity: Oral LD50 in rats (est. 940 mg/kg) reflects moderate toxicity, making caution essential during emergencies.
Routes of Entry: Skin absorption, inhalation, ingestion.
Symptoms of Overexposure: Headache, nausea, dizziness, respiratory distress, skin and eye redness.
Chronic Effects: In rare cases, extended exposure can cause hemolytic anemia, methemoglobinemia.
Carcinogenicity: Not classified as human carcinogen by main regulatory bodies, but lack of data urges continued caution.
Sensitivity: Some people experience allergic reactions with repeat or high-level contact, underscoring need for personal assessment.
Ecotoxicity: Information limited, probably low to moderate hazard to aquatic systems if released in quantity; few chronic data exist.
Mobility: High solubility in water suggests potential movement through soil if large spills reach outdoor environments.
Persistence and Degradability: Expected to degrade over time under normal environmental conditions, though precise breakdown rates need research.
Bioaccumulation: Low potential given its properties, but prevention of environmental release avoids unintended consequences.
Waste Treatment Methods: Collect contaminated material in designated, sealed waste containers, treat as hazardous waste.
Disposal: Incineration in controlled facilities or disposal via licensed chemical waste company, following national regulations.
Special Precautions: Do not flush down drains or discard with general refuse, separation from municipal waste streams protects water sources.
Container Disposal: Dispose of empty containers as hazardous waste after thorough triple-rinsing.
UN Number: Not assigned by UN for regular shipments; consult local guidelines.
Transport Hazard Class: Country-specific regulation applies; not commonly classified as dangerous for transport though care remains essential.
Packing Group: Refer to packaging standards matching chemical’s nature and quantity.
Special Precautions: Keep secure, upright, labeled, separate from foodstuffs and incompatible goods.
Environmental Hazards: Minimize spillage risk and environmental exposure during shipment.
Labeling Requirements: Follows GHS, OSHA Hazard Communication Standard in United States, similar regulatory bodies worldwide.
Inventory Listing: Included on TSCA, EINECS/ELINCS, and similar regional lists.
Restrictions: Subject to control for pharmaceutical or hazardous chemical use in many locations, ensuring only trained staff order or handle it.
Other Regulations: Compliance with workplace health and safety, waste management, and environmental protection laws is non-negotiable in registered facilities.
