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Material Safety Data Sheet (MSDS) for β-Glucanase

Identification

Product Name: β-Glucanase
Other Names: Endo-1,3(4)-β-glucanase, β-1,3/1,4-Glucanase
Chemical Family: Enzyme, Protein
Recommended Use: Industrial enzyme for brewing, animal feed, and food processing
Manufacturer Information: Contact information of supplier or manufacturer, including address, telephone, and emergency contact number
CAS Number: 62213-14-3
Emergency Telephone: Local emergency number and poison control center
Email: Emergency and non-emergency contact address for product inquirer

Hazard Identification

Classification: May cause allergy or asthma symptoms or breathing difficulties if inhaled, causes eye irritation
GHS Label Elements: Exclamation mark, Health hazard
Signal Word: Warning
Hazard Statements: Can trigger allergic reactions when inhaled, may irritate eyes and respiratory system
Precautionary Statements: Use only with adequate ventilation, avoid dust creation, do not breathe dust, wash hands thoroughly after handling, wear suitable gloves and eye protection

Composition / Information on Ingredients

Main Ingredient: β-Glucanase (Protein enzyme from Aspergillus or Trichoderma species)
Concentration: Varies, typically 10-90% dependent on source
Other Ingredients: May contain carriers such as dextrin, sodium chloride, or cellulose, minor stabilizers or preservatives
Impurities and Stabilizing Additives: Trace levels of manufacturing byproducts, processing aids

First Aid Measures

Inhalation: Move person to fresh air, monitor for any breathing difficulty, seek medical attention if symptoms persist
Skin Contact: Wash exposed area thoroughly with soap and water, remove contaminated clothing, seek advice if irritation remains
Eye Contact: Rinse eyes gently with water for several minutes, remove contact lenses if present and easy to do, seek medical attention if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, seek medical help if feeling unwell
Most Important Symptoms: Respiratory irritation, allergic reactions, eye redness or itchiness

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, CO2, or dry chemical
Unsuitable Extinguishing Media: Do not use high-pressure water jet
Special Hazards: Product dust may form explosive mixtures in air, combustion releases carbon oxides, nitrogen oxides, and potentially irritating fumes
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective clothing to prevent contact
Additional Advice: Prevent contaminated run-off from entering drains or watercourses

Accidental Release Measures

Personal Precautions: Restrict access to spill area, avoid dust formation, use personal protective equipment (respirator, goggles, gloves)
Environmental Precautions: Stop spill from reaching drains, water bodies, or soil
Methods for Cleaning Up: Gather spilled material without generating dust, use an air extractor or damp cloth for residue, place waste in designated container for disposal
Additional Information: Ventilate affected area, wash spill site after cleanup, notify proper authorities for large releases

Handling and Storage

Precautions for Safe Handling: Handle in well-ventilated spaces, avoid inhaling dust or aerosols, wear proper protective equipment, do not eat, drink, or smoke near product
Safe Storage Conditions: Store in original, tightly sealed container, keep in dry, cool, and ventilated place, away from direct sunlight, strong acids, and oxidizers
Special Risks: Keep containers closed when not in use, control dust formation, avoid storage with incompatible materials
Recommended Storage Temperature: 2–8°C, protect from freezing and moisture exposure

Exposure Controls and Personal Protection

Control Parameters: No established occupational exposure limit, follow local guidelines for enzymes and dust
Engineering Controls: Use adequate ventilation, process enclosures, or dust extraction systems
Individual Protection Measures:

  • Respiratory Protection: Approved particulate respirator for airborne dust
  • Eye/Face Protection: Safety goggles or face shield
  • Skin Protection: Protective gloves, laboratory coat or work clothing
  • General Hygiene Measures: Wash hands before breaks and after handling, do not touch face, eat or drink while using product

Physical and Chemical Properties

Appearance: Fine powder or granular solid, color ranges from off-white to light brown
Odor: Faint, slightly musty
Odor Threshold: Not established
pH: 4.0–7.0 (1% solution in water)
Melting / Freezing Point: Not applicable for enzyme powders
Boiling Point / Range: Not applicable
Flash Point: Not determined
Evaporation Rate: Not applicable
Flammability: Can form combustible dust clouds
Vapor Pressure: Not relevant
Vapor Density: Not relevant
Solubility: Soluble in water
Partition Coefficient: Not determined
Auto-Ignition Temperature: Not determined
Decomposition Temperature: Above 60°C possible enzyme deactivation
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Thermal Decomposition: Loses activity if stored or used above 40°C for extended periods
Possibility of Hazardous Reactions: Can react with strong oxidizers and acids
Conditions to Avoid: High temperatures, humidity, incompatible chemicals
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, and other organic fumes on combustion

Toxicological Information

Acute Toxicity: Low oral and dermal toxicity expected, may cause irritation to eyes and respiratory system
Skin Corrosion/Irritation: Mild irritation possible with prolonged or repeated contact
Serious Eye Damage/Irritation: Possible redness and discomfort
Respiratory or Skin Sensitization: May cause allergic reactions or asthma in sensitive individuals, especially after repeated exposure
Mutagenicity: Not classified as mutagenic
Carcinogenicity: No evidence of carcinogenic properties
Reproductive Toxicity: No data indicating risk
Specific Organ Toxicity: Prolonged inhalation may lead to respiratory sensitization
Other Relevant Effects: Allergic symptoms (coughing, wheezing, sneezing), eye watering, skin irritation

Ecological Information

Ecotoxicity: Low toxicity to aquatic organisms at typical environmental concentrations
Persistence and Degradability: Readily biodegradable, enzyme breaks down naturally
Bioaccumulative Potential: No significant bioaccumulation expected due to rapid biodegradation
Mobility in Soil: Limited persistence, high water solubility supports dispersion and degradation
Other Adverse Effects: No known long-term environmental hazards under normal conditions, product in high concentration may cause local oxygen demand

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, state, and federal regulations for enzyme-containing materials
Product Disposal: Can be incinerated or sent to landfill where permitted by local authority
Contaminated Packaging: Triple rinse and dispose as per regulations, recycling if possible
Precautions: Avoid disposal via sewage or natural water bodies, prevent dust release during disposal

Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Avoid extreme temperatures, protect packaging from crush or moisture during transit
Transport in Bulk: Not regulated, but containers must be secure to prevent spills

Regulatory Information

Safety, Health and Environmental Regulations: Product classified under common enzyme regulations, OSHA 29 CFR 1910 in the United States, EU CLP Regulation (EC) No 1272/2008
Labeling Requirements: Product labeling must include hazard pictograms and warning text per GHS/CLP rules
Inventory Listings: Listed or exempt under TSCA (US), EINECS/ELINCS (EU), DSL (Canada) where applicable
Restrictions: None identified for typical uses, observe workplace exposure controls
Other Regulations: Not subject to specific industrial safety legislation for dangerous chemicals, local and regional requirements may apply