Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
ZA9040000
CHEMICAL NAME :
Vitamin
K
CAS REGISTRY NUMBER :
12001-79-5
LAST UPDATED :
199701
HEALTH HAZARD
DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug
Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 8,25,1958 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo -
Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
13500
ug/kg
SEX/DURATION :
female 6-11 day(s) after conception
TOXIC EFFECTS
:
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and
tongue)
REFERENCE :
CAJPBD Proceedings of the Congenital Anomalies Research
Association of Japan. (Kyoto, Japan) No.1- 1961- Volume(issue)/page/year: 8,46,1968 ***
REVIEWS *** TOXICOLOGY REVIEW NYSJAM New York State Journal of Medicine. (Medical Soc. of
the State of New York, POB 5405, Lake Success, NY 11042) V.1- 1901- Volume(issue)/page/year:
64,493,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL
EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code -
80150 No. of Facilities: 168 (estimated) No. of Industries: 2 No. of Occupations: 12 No. of
Employees: 2650 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard
Code - 80150 No. of Facilities: 488 (estimated) No. of Industries: 3 No. of Occupations: 14
No. of Employees: 5168 (estimated) No. of Female Employees: 1116 (estimated)
